Compound Description
| ID: C0539 | Common name: Loganin |
| IUPAC: methyl (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate | CAS: CAS:18524-94-2 |
| Chembl ID: CHEMBL1081584 | Pubchem ID: CID:87691 |
| Formula: C17H26O10 | TCM-ID: TCMC2681 |
| Smiles: OC[C@H]1O[C@@H](O[C@@H]2OC=C([C@@H]3[C@H]2[C@@H](C)[C@H](C3)O)C(=O)OC)[C@@H]([C@H]([C@@H]1O)O)O | |
| Alias:
Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-, methyl ester;
Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-, methyl ester, [1S-(1α,4aα,6α,7α,7aα)]-; Loganin; (-)-Loganin; (1S)-1α-(β-D-Glucopyranosyloxy)-1,4aα,5,6,7,7aα-hexahydro-6α-hydroxy-7α-methylcyclopenta[c]pyran-4-carboxylic acid methyl ester; 7-Hydroxy-6-desoxyverbenalin; Loganoside; NSC 606403 |
Structure:
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Related Targets (Total: 3)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T04H8Y | Beta-secretase 1 | BACE1 |
P56817 |
A | 2 Reference(s) |
| T25Y64 | Cholinesterase | BCHE |
P06276 |
A | 1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
A | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 17)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0871 | Chuan Duan | 川断 | Teasels | Dipsacus asper |
| H0337 | Qin Jiao Hua | 秦艽花 | large-leaved gentian flower | Gentiana straminea |
| H0894 | Chuan Xu Duan | 川续断 | Himalayan teasel | Dipsacus asperoides |
| H0336 | Qin Jiao | 秦艽 | large-leaved gentian | Gentiana macrophylla |
| H1014 | Du Yi Wei | 独一味 | Common lamiophlomis | Lamiophlomis rotata |
| H0354 | Ren Dong Teng | 忍冬藤 | Japanese honeysuckle vine | Lonicera japonica |
| H0085 | Jiu Yu Rou | 酒萸肉 | Asiatic cornelian cherry | Cornus officinalis |
| H0064 | Jin Yin Hua | 金银花 | Japanese honeysuckle | Lonicera japonica |
| H1016 | Du Zhong Tan | 杜仲炭 | Eucommia | Eucommia ulmoides |
| H0203 | Ma Qian Zi Fen | 马钱子粉 | Nux vomica powder | Strychnos nux-vomica |
| H0807 | Zhi Ma Qian Zi | 炙马钱子 | Nux vomica | Strychnos nux-vomica |
| H1015 | Du Zhong | 杜仲 | Eucommia | Eucommia ulmoides |
| H0065 | Jin Yin Hua Ti Qu Ye | 金银花提取液 | Japanese honeysuckle | Lonicera japonica |
| H0202 | Ma Qian Zi | 马钱子 | Nut-vomitive poisonnut | Strychnos nux-vomica |
| H1138 | Bai Jiang Cao | 败酱草 | All - grass of dahurian patrinia | Thlaspi arvense |
| H0427 | Shan Zhu Yu | 山茱萸 | Asiatic cornelian cherry | Cornus officinalis |
| H1017 | Du Zhong Ye | 杜仲叶 | Eucommia leaf | Eucommia ulmoides |
Ckey description of the interaction between compound and target