Compound Description
| ID: C0869 | Common name: Alfatradiol |
| IUPAC: (8R,9S,13S,14S,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol | CAS: CAS:57-91-0 |
| Chembl ID: CHEMBL286452 | Pubchem ID: CID:68570 |
| Formula: C18H24O2 | TCM-ID: TCMC651 |
| Smiles: CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O | |
| Alias:
17α-Estradiol;
(17α)-Estra-1,3,5(10)-triene-3,17-diol; 1,3,5-Estratriene-3,17α-diol; 13β-Methyl-1,3,5(10)-gonatriene-3,17α-diol; 17-Epiestradiol; 17α-Oestradiol; 3,17-Dihydroxyestratriene; 3,17α-Dihydroxyestra-1,3,5(10)-triene; 3,17α-Dihydroxyoestra-1,3,5(10)-triene; Alfatradiol; Epiestradiol; Epiestrol; Estra-1,3,5(10)-triene-3,17α-diol; MIGENIX; MITO 4509; NSC 20293; Oestra-1,3,5(10)-triene-3,17α-diol; α-Estradiol |
Structure:
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Related Targets (Total: 5)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T88LSZ | Aromatase | CYP19A1 |
P11511 |
B | 1 Reference(s) |
| T01QLH | Estrogen receptor | ESR1 |
P03372 |
C | 1 Reference(s) |
| T86UXL | Cyclin-A2 | CCNA2 |
P20248 |
C | 1 Reference(s) |
| T93WZG | G1/S-specific cyclin-D1 | CCND1 |
P24385 |
C | 1 Reference(s) |
| T57RCH | Glutamate decarboxylase 2 | GAD2 |
Q05329 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 8)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0235 | Mao She Xiang | 毛麝香 | Abelmusk | Moschus moschiferus |
| H0236 | Mao She Xiang Jin Gao | 毛麝香浸膏 | Abelmusk | Moschus moschiferus |
| H0437 | She Xiang | 麝香 | Abelmusk | Moschus moschiferus |
| H0521 | Tai Pan Zu Zhi Fen | 胎盘组织粉 | NA | Human placenta |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0356 | Ren Gong She Xiang | 人工麝香 | Abelmusk | Moschus moschiferus |
| H0520 | Tai Pan Fen | 胎盘粉 | Fetus powder | Human placenta |
Ckey description of the interaction between compound and target