Compound Description
| ID: C0891 | Common name: Amentoflavone |
| IUPAC: 8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one | CAS: CAS:1617-53-4 |
| Chembl ID: CHEMBL63354 | Pubchem ID: CID:5281600 |
| Formula: C30H18O10 | TCM-ID: TCMC680 |
| Smiles: Oc1ccc(cc1)c1cc(=O)c2c(o1)c(c(cc2O)O)c1cc(ccc1O)c1cc(=O)c2c(o1)cc(cc2O)O | |
| Alias:
3''',8-Biflavone, 4',4''',5,5'',7,7''-hexahydroxy-;
Ginkgetin, didemethyl-; 8-[5-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Amenthoflavone; Amentoflavone; I3',II8-Biapigenin; NSC 295677; Tridemethylsciadopitysin |
Structure:
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Related Targets (Total: 4)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
A | 1 Reference(s) |
| T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
A | 1 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
C | 1 Reference(s) |
| T05WU9 | Serine/threonine-protein phosphatase 2A activator | PTPA |
Q15257 |
C | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 14)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0625 | Ce Bai Tan | 侧柏炭 | Oriental arbor-vitae | Platycladus orientalis |
| H0320 | Qi Shu Gen | 漆树根 | true lacquertree root | Toxicodendron succedaneum |
| H0214 | Bei He Huan | 北合欢 | Albizia | Albizia julibrissin |
| H0919 | Cui Yun Cao | 翠云草 | Hooked spikemoss | Selaginella uncinata |
| H0750 | Yin Xing Ye | 银杏叶 | Folium ginkgo | Ginkgo biloba |
| H0100 | Juan Bai | 卷柏 | Tamariskoid spikemoss | Selaginella tamariscina |
| H0181 | Luo Bu Ma | 罗布麻 | Dogbane | Apocynum venetum |
| H0071 | Bai Ye | 柏叶 | Chinese arborvitae twig | Platycladus orientalis |
| H0630 | Ce Bai Ye | 侧柏叶 | Chinese arborvitae leaf | Thuja orientalis |
| H1051 | Bai Guo | 白果 | Ginkgo nut | Ginkgo biloba |
| H0107 | Bai Zi Ren | 柏子仁 | Chinese arborvitae kernel | Biota orientalis |
| H1055 | Bai Guo Ren | 白果仁 | ginkgo | Ginkgo biloba |
| H0642 | Xiang Jia Pi | 香加皮 | Chinese silkvine root-bark | Periploca sepium |
| H0467 | Shi Shang Bai | 石上柏 | Doederlein's spikemoss herb | Herba selaginellae doederleinii |
Ckey description of the interaction between compound and target