Compound Description

ID:   C1094 Common name:   costunolide
IUPAC:  (3aS,6Z,10E,11aR)-6,10-dimethyl-3-methylidene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2-one CAS:  CAS:553-21-9
Chembl ID:   NA Pubchem ID:   CID:5380858
Formula:  C15H20O2 TCM-ID:  TCMC7531
Smiles:  CC1=CCCC(=CC2C(CC1)C(=C)C(=O)O2)C
Alias:

Costunolide (6CI);

Cyclodeca[b]furan-2(3H)-one, 3a,4,5,8,9,11a-hexahydro-6,10-dimethyl-3-methylene-, [3aS-(3aR*,6E,10E,11aS*)]-;

Germacra-1(10),4,11(13)-trien-12-oic acid, 6alpha-hydroxy-, gamma-lactone, (E,E)- (8CI);

(+)-Costunolide;

Costunolid;

Costus lactone;

NSC 106404
Structure:

Related Targets  (Total: 6)

Target idProtein NameGene SymbolUniprot IDTarget LevelNo.of Literature Evidence
T83M25 Beta-hexosaminidase subunit alphaHEXA P06865
A 1 Reference(s)
T78IOY Telomerase reverse transcriptaseTERT O14746
A 1 Reference(s)
T64T4I Telomerase protein component 1TEP1 Q99973
B 1 Reference(s)
T64BTV Interleukin-1 betaIL1B P01584
B 1 Reference(s)
T26KIE Transcription factor AP-1JUN P05412
C 1 Reference(s)
T79WXA Mitogen-activated protein kinase 1MAPK1 P28482
C 1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Related Herbs  (Total: 0)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name