Compound Description
| ID: C1235 | Common name: Cholic Acid |
| IUPAC: (4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid | CAS: CAS:81-25-4 |
| Chembl ID: CHEMBL205596 | Pubchem ID: CID:221493 |
| Formula: C24H40O5 | TCM-ID: TCMC903 |
| Smiles: O[C@@H]1CC[C@]2([C@@H](C1)C[C@H]([C@@H]1[C@@H]2C[C@H](O)[C@]2([C@H]1CC[C@@H]2[C@@H](CCC(=O)O)C)C)O)C | |
| Alias:
5β-Cholanic acid, 3α,7α,12α-trihydroxy-;
Cholic acid; (3α,5β,7α,12α)-3,7,12-Trihydroxycholan-24-oic acid; 17β-[1-Methyl-3-carboxypropyl]etiocholane-3α,7α,12α-triol; 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid; 3α,7α,12α-Trihydroxy-5β-cholanic acid; 3α,7α,12α-Trihydroxy-5β-cholanoic acid; 3α,7α,12α-Trihydroxy-β-cholanic acid; 3α,7α,12α-Trihydroxycholanic acid; 5β-Cholanic acid-3α,7α,12α-triol; 5β-Cholic acid; Cholalic acid; Cholalin; Cholbam; Colalin; E 1000; NSC-6135 |
Structure:
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Related Targets (Total: 1)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T50SX0 | Nuclear receptor subfamily 1 group I member 2 | NR1I2 |
O75469 |
B | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 9)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H0488 | Shui Niu Jiao Gan Jin Gao | 水牛角干浸膏 | Buffalo horn | Bubalus bubalis |
| H0355 | Ren Gong Niu Huang | 人工牛黄 | Artificial bezoar | Calculus bovis artificiosus |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0292 | Niu Jiao Jian Fen | 牛角尖粉 | Buffalo horn | Bubalus bubalis |
| H0487 | Shui Niu Jiao | 水牛角 | Buffalo horn | Bubalus bubalis |
| H0489 | Shui Niu Jiao Nong Suo Fen | 水牛角浓缩粉 | Buffalo horn | Bubalus bubalis |
| H0293 | Niu Jiao Tan | 牛角炭 | Buffalo horn | Bubalus bubalis |
| H0291 | Niu Jiao Fen | 牛角粉 | Buffalo horn | Bubalus bubalis |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
Ckey description of the interaction between compound and target