Target Description

Type Detail
Target ID T01FJS
Protein Name 3-oxo-5-alpha-steroid 4-dehydrogenase 1
Uniprot ID P18405
Protein Name Alias EC 1.3.1.22;  SR type 1;  Steroid 5-alpha-reductase 1;  S5AR 1
Gene ID 6715
Gene Symbol SRD5A1
Gene Alias NA
TTD T70309: Clinical Trial target
Pfam PF02544
GO
0042493:response to drug

0050213:progesterone 5-alpha-reductase activity

0006710:androgen catabolic process

0060348:bone development

0043627:response to estrogen

0042428:serotonin metabolic process

0021794:thalamus development

0070402:NADPH binding

0047751:cholestenone 5-alpha-reductase activity

0006694:steroid biosynthetic process

0071363:cellular response to growth factor stimulus

0009267:cellular response to starvation

0021854:hypothalamus development

0032869:cellular response to insulin stimulus

0071549:cellular response to dexamethasone stimulus

0060992:response to fungicide

0007530:sex determination

0070852:cell body fiber

0016491:oxidoreductase activity

0030539:male genitalia development

0016021:integral component of membrane

0001655:urogenital system development

0030540:female genitalia development

0021983:pituitary gland development

0043025:neuronal cell body

0071394:cellular response to testosterone stimulus

0016101:diterpenoid metabolic process

0071320:cellular response to cAMP

0005789:endoplasmic reticulum membrane

0021510:spinal cord development

0003865:3-oxo-5-alpha-steroid 4-dehydrogenase activity

0021766:hippocampus development

0048471:perinuclear region of cytoplasm

0008584:male gonad development

0071872:cellular response to epinephrine stimulus

0071392:cellular response to estradiol stimulus

0001889:liver development

0032354:response to follicle-stimulating hormone

0006702:androgen biosynthetic process

0030154:cell differentiation

0021987:cerebral cortex development

0014850:response to muscle activity

0009055:electron transfer activity

0042448:progesterone metabolic process

0043209:myelin sheath

0033218:amide binding

0060416:response to growth hormone

0042747:circadian sleep/wake cycle, REM sleep

PDB NA
Drugbank DB13943 ; DB01126 ; DB01420 ; DB01216 ; DB00421 ; DB13944 ; DB13946 ; DB09389 ; DB00367 ; DB06412 ; DB00717
KEGG hsa:6715

Related Compounds  (Total: 2)

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C0433
Name: Taxifolin
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C0587
Name: (+)-Taxifolin


Related Herbs  (Total: 24)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0045 Jin Fei Cao金沸草 Japanese inulaInula japonica
H1164 He Geng荷梗 Hindu lotus petioleNelumbo nucifera
H0379 Bian Xu萹蓄 Common knotgrassPolygonum aviculare
H0396 Sang Ye桑叶 White mulberry leafMorus alba
H0053 Jin Lian Hua金莲花 Chinese globeflowerTrollius chinensis
H1141 Guo Gang Long Jin Gao过岗龙浸膏 NAEntada phaseoloides
H0932 Ba Qia菝葜 Chinaroot greenbrierSmilax china
H0302 Ou Fen藕粉 Hindu lotus large rhizomeNelumbo nucifera
H1140 Guo Gang Long过岗龙 NAEntada phaseoloides
H0141 Lian Zi Xin莲子心 Hindu lotus plumuleNelumbo nucifera
H0642 Xiang Jia Pi香加皮 Chinese silkvine root-barkPeriploca sepium
H0570 Tu Fu Ling土茯苓 Glabrous greenbrierSmilax glabra
H0304 Ou Pian藕片 Hindu lotus large rhizomeNelumbo nucifera
H0214 Bei He Huan北合欢 AlbiziaAlbizia julibrissin
H0755 Ying Shan Hong映山红 Korean rhododendronRhododendron mucronulatum
H0369 Bian Fu Ge蝙蝠葛 Asiatic moonseedMenispermum dauricum
H1169 He Ye荷叶 Hindu lotus leafNelumbo nucifera
H0391 Sang Pi桑皮 Prepared root-bark white mulberryMorus alba
H0219 Man Shan Hong满山红 Dahurian rhododendronRhododendron dauricum
H0301 Ou Hindu lotus large rhizomeNelumbo nucifera
H0140 Lian Zi莲子 Hindu lotus seedNelumbo nucifera
H0397 Sang Zhi桑枝 White mulberry branchMorus alba
H0185 Luo Shi Teng络石藤 Chinese star jasmineTrachelospermum jasminoides
H0457 Shi Er石耳 Rock-EarsUmbilicaria esculenta