HIT-result

Type	Detail
Target ID	T08KSM
Protein Name	E3 ubiquitin-protein ligase SIAH2
Uniprot ID	O43255
Protein Name Alias	EC 2.3.2.27; RING-type E3 ubiquitin transferase SIAH2; Seven in absentia homolog 2; Siah-2; hSiah2
Gene ID	6478
Gene Symbol	SIAH2
Gene Alias	NA
TTD	NA
Pfam	PF03145
GO	0004842:ubiquitin-protein transferase activity 0044257:cellular protein catabolic process 0007275:multicellular organism development 0005829:cytosol 0042752:regulation of circadian rhythm 0006915:apoptotic process 0007049:cell cycle 0031396:regulation of protein ubiquitination 2001237:negative regulation of extrinsic apoptotic signaling pathway 0043161:proteasome-mediated ubiquitin-dependent protein catabolic process 0006511:ubiquitin-dependent protein catabolic process 0043005:neuron projection 0003714:transcription corepressor activity 0043231:intracellular membrane-bounded organelle 1902842:negative regulation of netrin-activated signaling pathway 0048511:rhythmic process 1990000:amyloid fibril formation 0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 0000209:protein polyubiquitination 0005769:early endosome 0008270:zinc ion binding 0005737:cytoplasm 0090090:negative regulation of canonical Wnt signaling pathway 0005654:nucleoplasm 0043025:neuronal cell body 0031624:ubiquitin conjugating enzyme binding 0061630:ubiquitin protein ligase activity 0016579:protein deubiquitination 0007264:small GTPase mediated signal transduction 0043066:negative regulation of apoptotic process
PDB	5H9M
Drugbank	NA
KEGG	hsa:6478

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Name: Menadione

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens