HIT-result

Type	Detail
Target ID	T08RKY
Protein Name	Mitogen-activated protein kinase 12
Uniprot ID	P53778
Protein Name Alias	MAP kinase 12; MAPK 12; EC 2.7.11.24; Extracellular signal-regulated kinase 6; ERK-6; Mitogen-activated protein kinase p38 gamma; MAP kinase p38 gamma; Stress-activated protein kinase 3
Gene ID	6300
Gene Symbol	MAPK12
Gene Alias	ERK6; SAPK3
TTD	T79798: Successful target
Pfam	PF00069
GO	0045445:myoblast differentiation 0004674:protein serine/threonine kinase activity 0006975:DNA damage induced protein phosphorylation 0035556:intracellular signal transduction 0000165:MAPK cascade 0005524:ATP binding 0051149:positive regulation of muscle cell differentiation 0106311:protein threonine kinase activity 0018105:peptidyl-serine phosphorylation 0010468:regulation of gene expression 0005829:cytosol 0007050:cell cycle arrest 0000287:magnesium ion binding 0005737:cytoplasm 0005654:nucleoplasm 0005739:mitochondrion 0010952:positive regulation of peptidase activity 0005634:nucleus 0007517:muscle organ development 0106310:protein serine kinase activity 0007165:signal transduction 0004707:MAP kinase activity
PDB	4QUM ; 1CM8 ; 6UNA
Drugbank	DB04395 ; DB05157 ; DB05403 ; DB01017 ; DB02482
KEGG	hsa:6300

Target Description