HIT-result

Type	Detail
Target ID	T09BGH
Protein Name	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
Uniprot ID	Q9P212
Protein Name Alias	EC 3.1.4.11; Pancreas-enriched phospholipase C; Phosphoinositide phospholipase C-epsilon-1; Phospholipase C-epsilon-1; PLC-epsilon-1
Gene ID	51196
Gene Symbol	PLCE1
Gene Alias	KIAA1516; PLCE; PPLC
TTD	NA
Pfam	PF00788 ; PF00388 ; PF09279 ; PF00617 ; PF00168 ; PF00387
GO	0001558:regulation of cell growth 0046578:regulation of Ras protein signal transduction 0016042:lipid catabolic process 0006940:regulation of smooth muscle contraction 0007507:heart development 0007265:Ras protein signal transduction 0007173:epidermal growth factor receptor signaling pathway 0005085:guanyl-nucleotide exchange factor activity 0005829:cytosol 0010592:positive regulation of lamellipodium assembly 0046872:metal ion binding 0043647:inositol phosphate metabolic process 0031267:small GTPase binding 0048016:inositol phosphate-mediated signaling 0007010:cytoskeleton organization 0006651:diacylglycerol biosynthetic process 0005886:plasma membrane 0019899:enzyme binding 0045859:regulation of protein kinase activity 0008277:regulation of G protein-coupled receptor signaling pathway 0048015:phosphatidylinositol-mediated signaling 0004435:phosphatidylinositol phospholipase C activity 0032835:glomerulus development 0007200:phospholipase C-activating G protein-coupled receptor signaling pathway 0000139:Golgi membrane 0000187:activation of MAPK activity 0004629:phospholipase C activity 0019722:calcium-mediated signaling 0007204:positive regulation of cytosolic calcium ion concentration 0030027:lamellipodium
PDB	2C5L ; 2BYF ; 2BYE
Drugbank	NA
KEGG	hsa:51196

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 0)