HIT-result

Type	Detail
Target ID	T11WKP
Protein Name	Poly [ADP-ribose] polymerase 2
Uniprot ID	Q9UGN5
Protein Name Alias	PARP-2; hPARP-2; EC 2.4.2.30; ADP-ribosyltransferase diphtheria toxin-like 2; ARTD2; DNA ADP-ribosyltransferase PARP2; EC 2.4.2.-; NAD(+) ADP-ribosyltransferase 2; ADPRT-2
Gene ID	10038
Gene Symbol	PARP2
Gene Alias	ADPRT2; ADPRTL2
TTD	T40812: Clinical Trial target
Pfam	PF00644 ; PF02877 ; PF05406
GO	0061051:positive regulation of cell growth involved in cardiac muscle cell development 0016570:histone modification 0070212:protein poly-ADP-ribosylation 0006281:DNA repair 0070213:protein auto-ADP-ribosylation 0006284:base-excision repair 1901215:negative regulation of neuron death 0031491:nucleosome binding 0090734:site of DNA damage 0003950:NAD+ ADP-ribosyltransferase activity 0030592:DNA ADP-ribosylation 0006471:protein ADP-ribosylation 0003682:chromatin binding 0018312:peptidyl-serine ADP-ribosylation 0140294:NAD DNA ADP-ribosyltransferase activity 0006302:double-strand break repair 0005730:nucleolus 0005634:nucleus 0097191:extrinsic apoptotic signaling pathway 0003677:DNA binding 1990404:protein ADP-ribosylase activity 0005654:nucleoplasm
PDB	6F1K ; 6F5F ; 3KJD ; 5D5K ; 6X0M ; 6TX3 ; 4ZZX ; 6F5B ; 5DSY ; 4PJV ; 6X0N ; 4TVJ ; 4ZZY ; 3KCZ ; 6USJ ; 6X0L
Drugbank	DB11793 ; DB12332 ; DB11760 ; DB07232 ; DB09074
KEGG	hsa:10038

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0257	Mo Gu	蘑菇	Mushroom	Agaricus campestris
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H1064	Ge Jie	蛤蚧	Tokay gecko	Gecko
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description