HIT-result

Type	Detail
Target ID	T11Z2G
Protein Name	B-lymphocyte antigen CD20
Uniprot ID	P11836
Protein Name Alias	B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; CD antigen CD20
Gene ID	931
Gene Symbol	MS4A1
Gene Alias	CD20
TTD	T73215: Successful target
Pfam	PF04103
GO	0070062:extracellular exosome 0023026:MHC class II protein complex binding 0005615:extracellular space 0050853:B cell receptor signaling pathway 0009986:cell surface 0042802:identical protein binding 0009897:external side of plasma membrane 0006959:humoral immune response 0005886:plasma membrane 0042100:B cell proliferation 1902656:calcium ion import into cytosol 0002115:store-operated calcium entry 0005654:nucleoplasm 0009617:response to bacterium 0005887:integral component of plasma membrane 0044853:plasma membrane raft 0019865:immunoglobulin binding 0030183:B cell differentiation 0005154:epidermal growth factor receptor binding 0042113:B cell activation 0051262:protein tetramerization
PDB	6Y92 ; 3BKY ; 6VJA ; 6Y9A ; 6Y90 ; 1S8B ; 3PP4 ; 6Y97 ; 2OSL
Drugbank	DB00078 ; DB00073 ; DB11988 ; DB00081 ; DB09336 ; DB06650 ; DB08935
KEGG	hsa:931

Target Description