HIT-result

Type	Detail
Target ID	T16FLN
Protein Name	Potassium voltage-gated channel subfamily A member 5
Uniprot ID	P22460
Protein Name Alias	HPCN1; Voltage-gated potassium channel HK2; Voltage-gated potassium channel subunit Kv1.5
Gene ID	3741
Gene Symbol	KCNA5
Gene Alias	NA
TTD	T17569: Successful target
Pfam	PF02214 ; PF00520
GO	0014704:intercalated disc 0042542:response to hydrogen peroxide 0043266:regulation of potassium ion transport 2000288:positive regulation of myoblast proliferation 0097110:scaffold protein binding 0055093:response to hyperoxia 0097623:potassium ion export across plasma membrane 0009612:response to mechanical stimulus 0086087:voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization 0042391:regulation of membrane potential 0019229:regulation of vasoconstriction 0086014:atrial cardiac muscle cell action potential 0086052:membrane repolarization during SA node cell action potential 0001666:response to hypoxia 0046691:intracellular canaliculus 0098914:membrane repolarization during atrial cardiac muscle cell action potential 0034705:potassium channel complex 0015271:outward rectifier potassium channel activity 0051481:negative regulation of cytosolic calcium ion concentration 1900087:positive regulation of G1/S transition of mitotic cell cycle 0050796:regulation of insulin secretion 0010033:response to organic substance 0019901:protein kinase binding 0005887:integral component of plasma membrane 0086090:voltage-gated potassium channel activity involved in SA node cell action potential repolarization 0005783:endoplasmic reticulum 0051393:alpha-actinin binding 0005886:plasma membrane 0030018:Z disc 0048471:perinuclear region of cytoplasm 0045121:membrane raft 0016021:integral component of membrane 0005249:voltage-gated potassium channel activity 0086089:voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization 0060081:membrane hyperpolarization 0008076:voltage-gated potassium channel complex 0009986:cell surface 0005794:Golgi apparatus 0007219:Notch signaling pathway 0005102:signaling receptor binding 0060372:regulation of atrial cardiac muscle cell membrane repolarization 0071805:potassium ion transmembrane transport 0006813:potassium ion transport 0086091:regulation of heart rate by cardiac conduction 0055075:potassium ion homeostasis 0005251:delayed rectifier potassium channel activity 0051260:protein homooligomerization 0086050:membrane repolarization during bundle of His cell action potential
PDB	NA
Drugbank	DB00228 ; DB06637 ; DB01069 ; DB06217 ; DB01110 ; DB11633
KEGG	hsa:3741

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Name: Dalfampridine

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0764	Yu Xing Cao	鱼腥草	Heartleaf houttuynia	Houttuynia cordata
H0524	Tan Xiang	檀香	Sandalwood	Santalum album