HIT-result

Type	Detail
Target ID	T21OUE
Protein Name	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Uniprot ID	Q9Y3Z3
Protein Name Alias	dNTPase; EC 3.1.5.-; Dendritic cell-derived IFNG-induced protein; DCIP; Monocyte protein 5; MOP-5; SAM domain and HD domain-containing protein 1; hSAMHD1
Gene ID	25939
Gene Symbol	SAMHD1
Gene Alias	MOP5
TTD	NA
Pfam	PF01966 ; PF07647
GO	0042802:identical protein binding 0005634:nucleus 0045088:regulation of innate immune response 0051607:defense response to virus 0006203:dGTP catabolic process 0005654:nucleoplasm 0097197:tetraspanin-enriched microdomain 0060337:type I interferon signaling pathway 0006955:immune response 0051289:protein homotetramerization 0004540:ribonuclease activity 0000724:double-strand break repair via homologous recombination 0032567:dGTP binding 0005886:plasma membrane 0016446:somatic hypermutation of immunoglobulin genes 0016793:triphosphoric monoester hydrolase activity 0008832:dGTPase activity 0060339:negative regulation of type I interferon-mediated signaling pathway 0009264:deoxyribonucleotide catabolic process 0110025:DNA strand resection involved in replication fork processing 0003676:nucleic acid binding 0003723:RNA binding 0003697:single-stranded DNA binding 0008270:zinc ion binding 0016032:viral process 0035861:site of double-strand break 0005525:GTP binding 0006974:cellular response to DNA damage stimulus 0046061:dATP catabolic process
PDB	6DWJ ; 4TO0 ; 4TO2 ; 6YOM ; 4RXQ ; 4QG1 ; 4TO4 ; 4ZWE ; 5AO0 ; 4QFY ; 4TO5 ; 6DW4 ; 4BZC ; 6TX0 ; 4TO6 ; 6CM2 ; 4QG2 ; 4ZWG ; 5AO3 ; 6DW7 ; 4QG0 ; 6U6Z ; 6DW5 ; 5AO4 ; 6XU1 ; 4RXP ; 4Q7H ; 4TNP ; 6U6Y ; 6TXC ; 4QFX ; 6DW3 ; 5AO2 ; 4TNR ; 4RXR ; 6DWD ; 2E8O ; 4MZ7 ; 6TXE ; 4RXO ; 4QG4 ; 4TNY ; 6U6X ; 4CC9 ; 4TNQ ; 6DWK ; 4QFZ ; 5AO1 ; 4TO3 ; 4TNZ ; 4RXS ; 4BZB ; 6TXA ; 3U1N ; 4TO1 ; 4TNX ; 6TXF
Drugbank	NA
KEGG	hsa:25939

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Name: Deoxyguanosine Triphosphate

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens