HIT-result

Type	Detail
Target ID	T23FZH
Protein Name	Lysine-specific demethylase 4C
Uniprot ID	Q9H3R0
Protein Name Alias	EC 1.14.11.66; Gene amplified in squamous cell carcinoma 1 protein; GASC-1 protein; JmjC domain-containing histone demethylation protein 3C; Jumonji domain-containing protein 2C
Gene ID	23081
Gene Symbol	KDM4C
Gene Alias	GASC1; JHDM3C; JMJD2C; KIAA0780
TTD	T73863: Patented target
Pfam	PF02375 ; PF02373 ; PF18104
GO	0019899:enzyme binding 0032452:histone demethylase activity 0008270:zinc ion binding 0000785:chromatin 0032454:histone demethylase activity (H3-K9 specific) 0070544:histone H3-K36 demethylation 0008284:positive regulation of cell population proliferation 0060765:regulation of androgen receptor signaling pathway 0006357:regulation of transcription by RNA polymerase II 0035097:histone methyltransferase complex 0005654:nucleoplasm 0006338:chromatin remodeling 0050681:androgen receptor binding 0051864:histone demethylase activity (H3-K36 specific) 0045666:positive regulation of neuron differentiation 0033169:histone H3-K9 demethylation 0003682:chromatin binding 0010628:positive regulation of gene expression
PDB	2XDP ; 5FJK ; 5KR7 ; 4XDO ; 2XML ; 4XDP ; 5FJH
Drugbank	NA
KEGG	hsa:23081

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description