HIT-result

Type	Detail
Target ID	T34RFK
Protein Name	MHC class II transactivator
Uniprot ID	P33076
Protein Name Alias	CIITA; EC 2.3.1.-; EC 2.7.11.1
Gene ID	4261
Gene Symbol	CIITA
Gene Alias	MHC2TA
TTD	NA
Pfam	PF05729 ; PF13516
GO	0016746:transferase activity, transferring acyl groups 0005654:nucleoplasm 0000976:transcription regulatory region sequence-specific DNA binding 0034341:response to interferon-gamma 0006954:inflammatory response 0106310:protein serine kinase activity 0032966:negative regulation of collagen biosynthetic process 0045893:positive regulation of transcription, DNA-templated 0000122:negative regulation of transcription by RNA polymerase II 0046677:response to antibiotic 0106311:protein threonine kinase activity 0046597:negative regulation of viral entry into host cell 0045892:negative regulation of transcription, DNA-templated 0060333:interferon-gamma-mediated signaling pathway 0005524:ATP binding 0045345:positive regulation of MHC class I biosynthetic process 0045348:positive regulation of MHC class II biosynthetic process 0005829:cytosol 0005525:GTP binding 0008022:protein C-terminus binding 0016605:PML body 0033613:activating transcription factor binding 0006955:immune response 0045944:positive regulation of transcription by RNA polymerase II 0044877:protein-containing complex binding 0003713:transcription coactivator activity
PDB	NA
Drugbank	NA
KEGG	hsa:4261

Target Description