HIT-result

Type	Detail
Target ID	T36S9V
Protein Name	Mucin-1
Uniprot ID	P15941
Protein Name Alias	MUC-1; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated mucin; CD antigen CD227
Gene ID	4582
Gene Symbol	MUC1
Gene Alias	PUM
TTD	T18779: Clinical Trial target
Pfam	PF01390
GO	0070062:extracellular exosome 0031982:vesicle 0005796:Golgi lumen 0006977:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 0005615:extracellular space 0090240:positive regulation of histone H4 acetylation 0043618:regulation of transcription from RNA polymerase II promoter in response to stress 0036003:positive regulation of transcription from RNA polymerase II promoter in response to stress 0010944:negative regulation of transcription by competitive promoter binding 0002223:stimulatory C-type lectin receptor signaling pathway 0003712:transcription coregulator activity 0005886:plasma membrane 0005887:integral component of plasma membrane 0002039:p53 binding 0005634:nucleus 0019221:cytokine-mediated signaling pathway 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 0033629:negative regulation of cell adhesion mediated by integrin 1902166:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 0000785:chromatin 0016266:O-glycan processing 0016324:apical plasma membrane 0006978:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
PDB	1SM3 ; 6FZQ ; 6TGG ; 6KX1 ; 6FZR ; 2ACM ; 5T6P ; 5T78 ; 2FO4
Drugbank	DB06584 ; DB11090
KEGG	hsa:4582

Go to browser

Name: Arctiin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0289	Niu Bang Zi	牛蒡子	Great burdock fruit	Arctium lappa
H0185	Luo Shi Teng	络石藤	Chinese star jasmine	Trachelospermum jasminoides