Target Description

Type Detail
Target ID T38JX9
Protein Name V-type proton ATPase 116 kDa subunit a3
Uniprot ID Q13488
Protein Name Alias V-ATPase 116 kDa subunit a3;  Osteoclastic proton pump 116 kDa subunit;  OC-116 kDa;  OC116;  T-cell immune regulator 1;  T-cell immune response cDNA7 protein;  TIRC7;  Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3
Gene ID 10312
Gene Symbol TCIRG1
Gene Alias ATP6N1C;  ATP6V0A3
TTD T80912: Research target
Pfam PF01496
GO
0097188:dentin mineralization

0005634:nucleus

0030316:osteoclast differentiation

0030217:T cell differentiation

0016236:macroautophagy

1902600:proton transmembrane transport

0006968:cellular defense response

0007039:protein catabolic process in the vacuole

0006915:apoptotic process

0006954:inflammatory response

0045667:regulation of osteoblast differentiation

0031529:ruffle organization

0016324:apical plasma membrane

0016471:vacuolar proton-transporting V-type ATPase complex

0071345:cellular response to cytokine stimulus

0000220:vacuolar proton-transporting V-type ATPase, V0 domain

0034198:cellular response to amino acid starvation

0050796:regulation of insulin secretion

0001503:ossification

0051117:ATPase binding

0030010:establishment of cell polarity

0030183:B cell differentiation

0043029:T cell homeostasis

0101003:ficolin-1-rich granule membrane

0005886:plasma membrane

0000045:autophagosome assembly

0021554:optic nerve development

0046961:proton-transporting ATPase activity, rotational mechanism

0005215:transporter activity

0016064:immunoglobulin mediated immune response

0010008:endosome membrane

0033365:protein localization to organelle

0002158:osteoclast proliferation

0010272:response to silver ion

0070166:enamel mineralization

0045453:bone resorption

0010468:regulation of gene expression

0005887:integral component of plasma membrane

0043312:neutrophil degranulation

0005765:lysosomal membrane

0007035:vacuolar acidification

0010155:regulation of proton transport

0005770:late endosome

0090383:phagosome acidification

0044691:tooth eruption

0033572:transferrin transport

0008284:positive regulation of cell population proliferation

0034220:ion transmembrane transport

0051650:establishment of vesicle localization

0061484:hematopoietic stem cell homeostasis

0006874:cellular calcium ion homeostasis

0010467:gene expression

0030670:phagocytic vesicle membrane

0008286:insulin receptor signaling pathway

0060041:retina development in camera-type eye

0035711:T-helper 1 cell activation

0035709:memory T cell activation

PDB NA
Drugbank DB01133
KEGG hsa:10312

Related Compounds  (Total: 1)

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C0897
Name: Anacardic Acid


Related Herbs  (Total: 10)

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