Target Description

Type Detail
Target ID T38ZYH
Protein Name Hypoxanthine-guanine phosphoribosyltransferase
Uniprot ID P00492
Protein Name Alias HGPRT;  HGPRTase;  EC 2.4.2.8
Gene ID 3251
Gene Symbol HPRT1
Gene Alias HPRT
TTD NA
Pfam PF00156
GO
0042802:identical protein binding

0006168:adenine salvage

0070062:extracellular exosome

0052657:guanine phosphoribosyltransferase activity

0046100:hypoxanthine metabolic process

0005829:cytosol

0000166:nucleotide binding

0046651:lymphocyte proliferation

0006178:guanine salvage

0007626:locomotory behavior

0048813:dendrite morphogenesis

0001975:response to amphetamine

0051289:protein homotetramerization

0045964:positive regulation of dopamine metabolic process

0006164:purine nucleotide biosynthetic process

0043101:purine-containing compound salvage

0001913:T cell mediated cytotoxicity

0046038:GMP catabolic process

0004422:hypoxanthine phosphoribosyltransferase activity

0000287:magnesium ion binding

0021756:striatum development

0043103:hypoxanthine salvage

0021895:cerebral cortex neuron differentiation

0032264:IMP salvage

0006166:purine ribonucleoside salvage

0021954:central nervous system neuron development

0032263:GMP salvage

0046040:IMP metabolic process

0042417:dopamine metabolic process

0005737:cytoplasm

0007625:grooming behavior

PDB 4RAO ; 4RAC ; 4RAQ ; 5BSK ; 6BNJ ; 1Z7G ; 3GEP ; 3GGJ ; 5W8V ; 1BZY ; 4RAD ; 5HIA ; 4KN6 ; 1HMP ; 4RAB ; 4RAN ; 1D6N ; 2VFA ; 3GGC ; 4IJQ ; 5BRN
Drugbank DB00352 ; DB01033 ; DB04356 ; DB00993 ; DB03153 ; DB01632 ; DB02309
KEGG hsa:3251

Related Compounds  (Total: 1)

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C0876
Name: Allopurinol


Related Herbs  (Total: 2)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0847 Zi He Che紫河车 Human placentaHomo sapiens