HIT-result

Type	Detail
Target ID	T50PIC
Protein Name	T-box transcription factor TBX21
Uniprot ID	Q9UL17
Protein Name Alias	T-box protein 21; T-cell-specific T-box transcription factor T-bet; Transcription factor TBLYM
Gene ID	30009
Gene Symbol	TBX21
Gene Alias	TBET; TBLYM
TTD	T26741: Research target
Pfam	PF00907
GO	0005634:nucleus 0007275:multicellular organism development 0071310:cellular response to organic substance 0043565:sequence-specific DNA binding 0006355:regulation of transcription, DNA-templated 0001947:heart looping 0045892:negative regulation of transcription, DNA-templated 2000329:negative regulation of T-helper 17 cell lineage commitment 0043161:proteasome-mediated ubiquitin-dependent protein catabolic process 0030217:T cell differentiation 2000320:negative regulation of T-helper 17 cell differentiation 0000976:transcription regulatory region sequence-specific DNA binding 0045580:regulation of T cell differentiation 0009615:response to virus 0000981:DNA-binding transcription factor activity, RNA polymerase II-specific 0045893:positive regulation of transcription, DNA-templated 0000122:negative regulation of transcription by RNA polymerase II 2000552:negative regulation of T-helper 2 cell cytokine production 0003700:DNA-binding transcription factor activity 0072676:lymphocyte migration 0032703:negative regulation of interleukin-2 production 0006357:regulation of transcription by RNA polymerase II 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 0001227:DNA-binding transcription repressor activity, RNA polymerase II-specific 0043025:neuronal cell body 1990837:sequence-specific double-stranded DNA binding 0048304:positive regulation of isotype switching to IgG isotypes 0001708:cell fate specification
PDB	NA
Drugbank	NA
KEGG	hsa:30009

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 1)