HIT-result

Type	Detail
Target ID	T50S1H
Protein Name	Dual specificity protein kinase TTK
Uniprot ID	P33981
Protein Name Alias	EC 2.7.12.1; Phosphotyrosine picked threonine-protein kinase; PYT
Gene ID	7272
Gene Symbol	TTK
Gene Alias	MPS1; MPS1L1
TTD	T74977: Clinical Trial target
Pfam	PF00069
GO	0005634:nucleus 0010862:positive regulation of pathway-restricted SMAD protein phosphorylation 0046777:protein autophosphorylation 0106310:protein serine kinase activity 0004674:protein serine/threonine kinase activity 0106311:protein threonine kinase activity 0043515:kinetochore binding 0004713:protein tyrosine kinase activity 0005819:spindle 0008284:positive regulation of cell population proliferation 0018105:peptidyl-serine phosphorylation 0007052:mitotic spindle organization 0016321:female meiosis chromosome segregation 0051304:chromosome separation 0007051:spindle organization 0004712:protein serine/threonine/tyrosine kinase activity 0005524:ATP binding 1903096:protein localization to meiotic spindle midzone 0018107:peptidyl-threonine phosphorylation 0007094:mitotic spindle assembly checkpoint 0007059:chromosome segregation 0016020:membrane 0000776:kinetochore 0004714:transmembrane receptor protein tyrosine kinase activity 0033316:meiotic spindle assembly checkpoint 0005737:cytoplasm 0034501:protein localization to kinetochore
PDB	3WZK ; 4JT3 ; 3DBQ ; 3VQU ; 3WYY ; 4C4G ; 4C4I ; 2ZMD ; 5AP4 ; 5N84 ; 4BI2 ; 5AP3 ; 5AP1 ; 5EI8 ; 5N93 ; 4H7X ; 4JS8 ; 5EHL ; 5LJJ ; 6B4W ; 6TNC ; 3HMO ; 4ZEG ; 5EI6 ; 6TN9 ; 6N6O ; 5AP0 ; 5N7V ; 4CVA ; 6H3K ; 4O6L ; 2ZMC ; 5AP7 ; 5EI2 ; 5NAD ; 4BI0 ; 4CV8 ; 5AP5 ; 4D2S ; 4C4H ; 5O91 ; 3WZJ ; 3HMN ; 4C4E ; 6GVJ ; 4C4J ; 5N87 ; 5NTT ; 4C4F ; 4H7Y ; 5AP2 ; 6TNB ; 3HMP ; 3W1F ; 5AP6 ; 5EHO ; 5MRB ; 5NA0 ; 3H9F ; 4CV9 ; 5EHY ; 4B94 ; 5N9S ; 5EH0 ; 3WYX ; 6TND ; 3GFW ; 2X9E ; 3CEK ; 4BHZ ; 4BI1
Drugbank	DB01782 ; DB15498 ; DB12010
KEGG	hsa:7272

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Name: Pyridine

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0750	Yin Xing Ye	银杏叶	Folium ginkgo	Ginkgo biloba
H0354	Ren Dong Teng	忍冬藤	Japanese honeysuckle vine	Lonicera japonica
H0416	Shan Shen	山参	NA	Panax ginseng
H0334	Bi Ma Ren	蓖麻仁	Ricinus	Ricinus communis
H0064	Jin Yin Hua	金银花	Japanese honeysuckle	Lonicera japonica
H0321	Bi Ma	蓖麻	castor oil plant	Ricinus communis
H0340	Bi Ma Zi	蓖麻子	Castorbean seed	Ricinus communis
H0357	Ren Shen	人参	Ginseng	Panax ginseng
H0358	Ren Shen Ye	人参叶	Ginseng leaf	Panax ginseng
H1051	Bai Guo	白果	Ginkgo nut	Ginkgo biloba
H0065	Jin Yin Hua Ti Qu Ye	金银花提取液	Japanese honeysuckle	Lonicera japonica
H0326	Bi Ma Gen	蓖麻根	Castorbean root	Ricinus communis
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H1055	Bai Guo Ren	白果仁	ginkgo	Ginkgo biloba