HIT-result

Type	Detail
Target ID	T55VJ9
Protein Name	Thymidine phosphorylase
Uniprot ID	P19971
Protein Name Alias	TP; EC 2.4.2.4; Gliostatin; Platelet-derived endothelial cell growth factor; PD-ECGF; TdRPase
Gene ID	1890
Gene Symbol	TYMP
Gene Alias	ECGF1
TTD	T59929: Successful target
Pfam	PF02885 ; PF07831 ; PF00591
GO	0006206:pyrimidine nucleobase metabolic process 0043097:pyrimidine nucleoside salvage 0031641:regulation of myelination 0001525:angiogenesis 0005829:cytosol 0004645:1,4-alpha-oligoglucan phosphorylase activity 0006935:chemotaxis 0046074:dTMP catabolic process 1905333:regulation of gastric motility 0046135:pyrimidine nucleoside catabolic process 0016154:pyrimidine-nucleoside phosphorylase activity 0006213:pyrimidine nucleoside metabolic process 0030154:cell differentiation 0051969:regulation of transmission of nerve impulse 0008083:growth factor activity 0009032:thymidine phosphorylase activity 0042803:protein homodimerization activity 0000002:mitochondrial genome maintenance
PDB	2WK5 ; 1UOU ; 2J0F ; 2WK6
Drugbank	DB09343 ; DB01101 ; DB00322 ; DB00544 ; DB06433 ; DB00432 ; DB00369
KEGG	hsa:1890

Target Description