HIT-result

Type	Detail
Target ID	T56VPC
Protein Name	Cathepsin S
Uniprot ID	P25774
Protein Name Alias	EC 3.4.22.27
Gene ID	1520
Gene Symbol	CTSS
Gene Alias	NA
TTD	T68290: Clinical Trial target
Pfam	PF08246 ; PF00112
GO	0036021:endolysosome lumen 0043236:laminin binding 0097067:cellular response to thyroid hormone stimulus 0002224:toll-like receptor signaling pathway 0002250:adaptive immune response 0016485:protein processing 0062023:collagen-containing extracellular matrix 1904724:tertiary granule lumen 0005518:collagen binding 0048002:antigen processing and presentation of peptide antigen 0043202:lysosomal lumen 0006508:proteolysis 0043231:intracellular membrane-bounded organelle 0045335:phagocytic vesicle 0034769:basement membrane disassembly 0005576:extracellular region 0051603:proteolysis involved in cellular protein catabolic process 0004197:cysteine-type endopeptidase activity 0010447:response to acidic pH 0005615:extracellular space 0043394:proteoglycan binding 0001968:fibronectin binding 1904813:ficolin-1-rich granule lumen 0030574:collagen catabolic process 2001259:positive regulation of cation channel activity 0019886:antigen processing and presentation of exogenous peptide antigen via MHC class II 0043312:neutrophil degranulation 0005770:late endosome 0006955:immune response 0019882:antigen processing and presentation 0005764:lysosome 0022617:extracellular matrix disassembly
PDB	2G6D ; 1NPZ ; 2FQ9 ; 2R9M ; 2G7Y ; 5QC9 ; 1NQC ; 5QCC ; 2FYE ; 1GLO ; 5QC7 ; 2C0Y ; 1MS6 ; 5QCD ; 5QCI ; 4P6G ; 2FRQ ; 5QC8 ; 2OP3 ; 5QC4 ; 5QBV ; 5QBX ; 5QCJ ; 2FRA ; 2HHN ; 5QC6 ; 5QBU ; 3OVX ; 4P6E ; 5QBZ ; 5QC1 ; 5QC2 ; 2H7J ; 3N3G ; 2R9N ; 5QCF ; 5QBY ; 2F1G ; 5QCA ; 2HXZ ; 3IEJ ; 5QC0 ; 5QC5 ; 5QCE ; 2HH5 ; 1BXF ; 2FT2 ; 5QCB ; 2R9O ; 5QCG ; 5QC3 ; 3N4C ; 2FUD ; 5QCH ; 5QBW
Drugbank	DB07839 ; DB03984 ; DB08195 ; DB07878 ; DB08611 ; DB03767 ; DB08752 ; DB07587 ; DB03837 ; DB08755 ; DB07520 ; DB07589 ; DB12010
KEGG	hsa:1520

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Name: (R)-Cysteine

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H1168	He Tao Ren	核桃仁	English walnut seed	Semen juglandis
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0151	Ling Yang Jiao	羚羊角	Antelope horn	Cornu saigae tataricae
H1167	He Tao	核桃	English walnut seed	Semen juglandis
H0484	Shui Fei Ji	水飞蓟	St marys	Silybum marianum
H0043	Jie Zi	芥子	India mustard seed	Brassica juncea
H1152	Bai Jie Zi	白芥子	White mustard seed	Sinapis alba
H1110	Gua Lou Zi	瓜蒌子	mongolian snakegourd seed	Trichosanthes kirilowii maxim