HIT-result

Target Description

Type	Detail
Target ID	T57BCQ
Protein Name	Exportin-1
Uniprot ID	O14980
Protein Name Alias	Exp1; Chromosome region maintenance 1 protein homolog
Gene ID	7514
Gene Symbol	XPO1
Gene Alias	CRM1
TTD	T51407: Clinical Trial target
Pfam	PF03810 ; PF08767 ; PF18784 ; PF18787 ; PF18777 ; PF08389
GO	0006913:nucleocytoplasmic transport 0015030:Cajal body 0005634:nucleus 0043488:regulation of mRNA stability 0006611:protein export from nucleus 0005642:annulate lamellae 0005049:nuclear export signal receptor activity 0005829:cytosol 0042254:ribosome biogenesis 0000055:ribosomal large subunit export from nucleus 0051028:mRNA transport 0007052:mitotic spindle organization 0005737:cytoplasm 0005635:nuclear envelope 0032434:regulation of proteasomal ubiquitin-dependent protein catabolic process 0043231:intracellular membrane-bounded organelle 0075733:intracellular transport of virus 0031965:nuclear membrane 0005730:nucleolus 0043657:host cell 1990904:ribonucleoprotein complex 0016020:membrane 0003723:RNA binding 0031267:small GTPase binding 0032991:protein-containing complex 0000776:kinetochore 0000054:ribosomal subunit export from nucleus 0016032:viral process 0005654:nucleoplasm 0000056:ribosomal small subunit export from nucleus
PDB	3GB8 ; 4BSM ; 5DIS ; 4BSN ; 1W9C ; 2L1L ; 6TVO
Drugbank	DB11942
KEGG	hsa:7514

Type

Detail

Target ID

T57BCQ

Protein Name

Exportin-1

Uniprot ID

O14980

Protein Name Alias

Exp1; Chromosome region maintenance 1 protein homolog

Gene ID

7514

Gene Symbol

XPO1

Gene Alias

CRM1

TTD

T51407: Clinical Trial target

Pfam

PF03810 ; PF08767 ; PF18784 ; PF18787 ; PF18777 ; PF08389

0006913:nucleocytoplasmic transport

0015030:Cajal body

0005634:nucleus

0043488:regulation of mRNA stability

0006611:protein export from nucleus

0005642:annulate lamellae

0005049:nuclear export signal receptor activity

0005829:cytosol

0042254:ribosome biogenesis

0000055:ribosomal large subunit export from nucleus

0051028:mRNA transport

0007052:mitotic spindle organization

0005737:cytoplasm

0005635:nuclear envelope

0032434:regulation of proteasomal ubiquitin-dependent protein catabolic process

0043231:intracellular membrane-bounded organelle

0075733:intracellular transport of virus

0031965:nuclear membrane

0005730:nucleolus

0043657:host cell

1990904:ribonucleoprotein complex

0016020:membrane

0003723:RNA binding

0031267:small GTPase binding

0032991:protein-containing complex

0000776:kinetochore

0000054:ribosomal subunit export from nucleus

0016032:viral process

0005654:nucleoplasm

0000056:ribosomal small subunit export from nucleus

PDB

3GB8 ; 4BSM ; 5DIS ; 4BSN ; 1W9C ; 2L1L ; 6TVO

Drugbank

DB11942

KEGG

hsa:7514

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0805	Zhi Ke Gan Jin Gao	枳壳干浸膏	Seville ora nge unripe fruit	Citrus aurantium
H0604	Wu Wei Teng	五味藤	NA	Securidaca inappendiculata
H0804	Zhi Ke	枳壳	Seville ora nge unripe fruit	Citrus aurantium
H0652	Xiang Yuan Pi	香橼皮	Wilson citron	Citrus medica
H0802	Zhi Geng	枳梗	NA	Citrus aurantium
H0651	Xiang Yuan	香橼	Wilson citron	Citrus medica
H0813	Zhi Shi	枳实	Seville orange young fruit	Citrus aurantium
H0758	Cheng Pi	橙皮	Bitter orange	Citrus aurantium
H0084	Jiu Li Xiang	九里香	Common jasminorange	Murraya paniculata
H0088	Ju He	橘核	Tangerine seed	Citrus reticulata
H0093	Ju Pi	橘皮	Tangerine pericarp	Citrus reticulata

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 11)