HIT-result

Type	Detail
Target ID	T57OPG
Protein Name	Cyclin-dependent kinase 5 activator 1
Uniprot ID	Q15078
Protein Name Alias	CDK5 activator 1; Cyclin-dependent kinase 5 regulatory subunit 1; TPKII regulatory subunit
Gene ID	8851
Gene Symbol	CDK5R1
Gene Alias	CDK5R; NCK5A
TTD	T09513: Research target
Pfam	PF03261
GO	0030182:neuron differentiation 0005634:nucleus 0045348:positive regulation of MHC class II biosynthetic process 0045664:regulation of neuron differentiation 0048013:ephrin receptor signaling pathway 0014069:postsynaptic density 0005829:cytosol 0030425:dendrite 0048487:beta-tubulin binding 0045296:cadherin binding 0016301:kinase activity 0030295:protein kinase activator activity 0021819:layer formation in cerebral cortex 0016020:membrane 0007411:axon guidance 0004672:protein kinase activity 0018107:peptidyl-threonine phosphorylation 0031594:neuromuscular junction 0045892:negative regulation of transcription, DNA-templated 0098793:presynapse 0007158:neuron cell-cell adhesion 0000079:regulation of cyclin-dependent protein serine/threonine kinase activity 0043231:intracellular membrane-bounded organelle 0032956:regulation of actin cytoskeleton organization 1901796:regulation of signal transduction by p53 class mediator 0005654:nucleoplasm 0009792:embryo development ending in birth or egg hatching 0061575:cyclin-dependent protein serine/threonine kinase activator activity 0035255:ionotropic glutamate receptor binding 0043539:protein serine/threonine kinase activator activity 0051015:actin filament binding 0016533:protein kinase 5 complex 2000273:positive regulation of signaling receptor activity 0046875:ephrin receptor binding 0007420:brain development 0021766:hippocampus development 0030517:negative regulation of axon extension 0031175:neuron projection development 0042501:serine phosphorylation of STAT protein 0098693:regulation of synaptic vesicle cycle 0000226:microtubule cytoskeleton organization 0043014:alpha-tubulin binding 0016241:regulation of macroautophagy 0043197:dendritic spine 0018105:peptidyl-serine phosphorylation 0021549:cerebellum development 0035235:ionotropic glutamate receptor signaling pathway 0001764:neuron migration 0030426:growth cone 0043025:neuronal cell body 0043292:contractile fiber 0005886:plasma membrane 0007413:axonal fasciculation 0031116:positive regulation of microtubule polymerization 0043204:perikaryon 0002020:protease binding 0043525:positive regulation of neuron apoptotic process 0090314:positive regulation of protein targeting to membrane 0048511:rhythmic process 0061001:regulation of dendritic spine morphogenesis 0019901:protein kinase binding 0071158:positive regulation of cell cycle arrest 0021722:superior olivary nucleus maturation 0030424:axon 0043005:neuron projection 0005737:cytoplasm 0048471:perinuclear region of cytoplasm 0005509:calcium ion binding 0007213:G protein-coupled acetylcholine receptor signaling pathway
PDB	1UNL ; 7CNG ; 3O0G ; 1H4L ; 1UNG ; 1UNH ; 6LDP
Drugbank	DB07364 ; DB02052
KEGG	hsa:8851

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Name: ginsenoside rb1

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name