Target Description

Type Detail
Target ID T59C5R
Protein Name Serine/threonine-protein kinase B-raf
Uniprot ID P15056
Protein Name Alias EC 2.7.11.1;  Proto-oncogene B-Raf;  p94;  v-Raf murine sarcoma viral oncogene homolog B1
Gene ID 673
Gene Symbol BRAF
Gene Alias BRAF1;  RAFB1
TTD T99089: Successful target
Pfam PF02196 ; PF00130 ; PF07714
GO
0042802:identical protein binding

0005634:nucleus

0090150:establishment of protein localization to membrane

0004672:protein kinase activity

0106310:protein serine kinase activity

0010828:positive regulation of glucose transmembrane transport

0097110:scaffold protein binding

0004674:protein serine/threonine kinase activity

0106311:protein threonine kinase activity

0005509:calcium ion binding

0000165:MAPK cascade

0005829:cytosol

0010628:positive regulation of gene expression

0005524:ATP binding

0005886:plasma membrane

0043231:intracellular membrane-bounded organelle

0070374:positive regulation of ERK1 and ERK2 cascade

0071277:cellular response to calcium ion

0007173:epidermal growth factor receptor signaling pathway

0006468:protein phosphorylation

0033138:positive regulation of peptidyl-serine phosphorylation

0000186:activation of MAPKK activity

0070413:trehalose metabolism in response to stress

0043066:negative regulation of apoptotic process

0009887:animal organ morphogenesis

PDB 6Q0J ; 5CT7 ; 6V2X ; 3II5 ; 4KSP ; 6V2Y ; 6UUO ; 4MBJ ; 5J18 ; 5JT2 ; 5HID ; 5CSW ; 1UWJ ; 3PRI ; 4DBN ; 6UAN ; 6Q0K ; 3PPJ ; 5J2R ; 2L05 ; 4XV2 ; 6V31 ; 4H58 ; 4MNE ; 6NYB ; 4MNF ; 6P7G ; 4JVG ; 6CAD ; 4R5Y ; 4EHG ; 4XV9 ; 3C4C ; 4EHE ; 4XV3 ; 3TV6 ; 3D4Q ; 4G9C ; 5FD2 ; 3IDP ; 5JRQ ; 6Q0T ; 3PSD ; 4E26 ; 6N0P ; 6U2H ; 2FB8 ; 5HIE ; 3NY5 ; 4FK3 ; 6V2W ; 6V2U ; 3PPK ; 5HI2 ; 3Q96 ; 1UWH ; 5JSM ; 3OG7 ; 6P3D ; 6V2Z ; 4CQE ; 5VYK ; 6V32 ; 4XV1 ; 3PSB ; 5VAL ; 4YHT ; 5C9C ; 6XAG ; 5J17 ; 4PP7 ; 5VAM ; 4RZW ; 5CSX ; 6V2V ; 4FC0 ; 4KSQ ; 4E4X ; 5VR3 ; 6U2G ; 4WO5 ; 3TV4 ; 3PRF ; 6NSQ ; 6N0Q ; 5ITA ; 3Q4C ; 4G9R ; 4RZV ; 3SKC ; 6V30 ; 6B8U ; 6PP9
Drugbank DB00398 ; DB08553 ; DB07000 ; DB12010 ; DB08881 ; DB14840 ; DB05190 ; DB11718 ; DB08912 ; DB08896 ; DB05984 ; DB06999
KEGG hsa:673

Related Compounds  (Total: 1)

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C1198
Name: Butanone


Related Herbs  (Total: 3)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0173 Lu Hui芦荟 Kulaso aloe dried juiceAloe vera
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens