HIT-result

Type	Detail
Target ID	T62QAR
Protein Name	N-lysine methyltransferase SMYD2
Uniprot ID	Q9NRG4
Protein Name Alias	EC 2.1.1.-; HSKM-B; Histone methyltransferase SMYD2; EC 2.1.1.354; Lysine N-methyltransferase 3C; SET and MYND domain-containing protein 2
Gene ID	56950
Gene Symbol	SMYD2
Gene Alias	KMT3C
TTD	T15797: Preclinical target
Pfam	PF00856 ; PF01753
GO	0018027:peptidyl-lysine dimethylation 0005634:nucleus 0005737:cytoplasm 0008285:negative regulation of cell population proliferation 0018024:histone-lysine N-methyltransferase activity 0000993:RNA polymerase II complex binding 0005654:nucleoplasm 0046872:metal ion binding 0034968:histone lysine methylation 1901796:regulation of signal transduction by p53 class mediator 0046975:histone methyltransferase activity (H3-K36 specific) 0005829:cytosol 0007507:heart development 0016279:protein-lysine N-methyltransferase activity 0043516:regulation of DNA damage response, signal transduction by p53 class mediator 0018026:peptidyl-lysine monomethylation 0002039:p53 binding 0000122:negative regulation of transcription by RNA polymerase II
PDB	3RIB ; 3TG4 ; 5V3H ; 5ARG ; 5KJN ; 6CBY ; 6N3G ; 6CBX ; 4YND ; 4O6F ; 4WUY ; 3S7F ; 5ARF ; 3S7D ; 5KJL ; 6MON ; 5KJK ; 5KJM ; 3TG5 ; 3S7B ; 3S7J ; 5WCG
Drugbank	NA
KEGG	hsa:56950

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens

Target Description