HIT-result

Type	Detail
Target ID	T69VDZ
Protein Name	B-cell lymphoma 3 protein
Uniprot ID	P20749
Protein Name Alias	BCL-3; Proto-oncogene BCL3
Gene ID	602
Gene Symbol	BCL3
Gene Alias	BCL4; D19S37
TTD	NA
Pfam	PF12796 ; PF00023
GO	0042771:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 0051457:maintenance of protein location in nucleus 0005654:nucleoplasm 0042832:defense response to protozoan 0042742:defense response to bacterium 0002455:humoral immune response mediated by circulating immunoglobulin 0032720:negative regulation of tumor necrosis factor production 0009615:response to virus 0042088:T-helper 1 type immune response 0032733:positive regulation of interleukin-10 production 0010225:response to UV-C 0006351:transcription, DNA-templated 0043231:intracellular membrane-bounded organelle 0030330:DNA damage response, signal transduction by p53 class mediator 0042981:regulation of apoptotic process 0030674:protein-macromolecule adaptor activity 0045727:positive regulation of translation 0005886:plasma membrane 0045893:positive regulation of transcription, DNA-templated 0032996:Bcl3-Bcl10 complex 0033257:Bcl3/NF-kappaB2 complex 0005829:cytosol 0043066:negative regulation of apoptotic process 0045892:negative regulation of transcription, DNA-templated 0002467:germinal center formation 0048471:perinuclear region of cytoplasm 0007249:I-kappaB kinase/NF-kappaB signaling 0005634:nucleus 0008134:transcription factor binding 0045064:T-helper 2 cell differentiation 0002268:follicular dendritic cell differentiation 0032717:negative regulation of interleukin-8 production 0019730:antimicrobial humoral response 0032991:protein-containing complex 0002315:marginal zone B cell differentiation 0006974:cellular response to DNA damage stimulus 0030198:extracellular matrix organization 0048536:spleen development 0030496:midbody 0005737:cytoplasm 0032729:positive regulation of interferon-gamma production 0045944:positive regulation of transcription by RNA polymerase II 0051101:regulation of DNA binding 0046426:negative regulation of receptor signaling pathway via JAK-STAT 1901222:regulation of NIK/NF-kappaB signaling 0003713:transcription coactivator activity
PDB	1K1B ; 1K1A
Drugbank	NA
KEGG	hsa:602

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Name: Aminosalicylic Acid

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0327	Qian Li Guang	千里光	Climbing groundsel	Senecio scandens