HIT-result

Type	Detail
Target ID	T70MSG
Protein Name	Arginase-2, mitochondrial
Uniprot ID	P78540
Protein Name Alias	EC 3.5.3.1; Arginase II; Kidney-type arginase; Non-hepatic arginase; Type II arginase
Gene ID	384
Gene Symbol	ARG2
Gene Alias	NA
TTD	T36806: Clinical Trial target
Pfam	PF00491
GO	0032720:negative regulation of tumor necrosis factor production 2000774:positive regulation of cellular senescence 0002829:negative regulation of type 2 immune response 1905403:negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process 0071641:negative regulation of macrophage inflammatory protein 1 alpha production 1903426:regulation of reactive oxygen species biosynthetic process 0004053:arginase activity 0001657:ureteric bud development 1900425:negative regulation of defense response to bacterium 0002250:adaptive immune response 0032651:regulation of interleukin-1 beta production 0005737:cytoplasm 0045087:innate immune response 0032700:negative regulation of interleukin-17 production 0071644:negative regulation of chemokine (C-C motif) ligand 4 production 0006941:striated muscle contraction 0071650:negative regulation of chemokine (C-C motif) ligand 5 production 0005739:mitochondrion 0030145:manganese ion binding 0006809:nitric oxide biosynthetic process 2000562:negative regulation of CD4-positive, alpha-beta T cell proliferation 0005759:mitochondrial matrix 0032696:negative regulation of interleukin-13 production 0019547:arginine catabolic process to ornithine 0000050:urea cycle
PDB	6Q39 ; 4IXV ; 1PQ3 ; 6SS2 ; 6Q37 ; 4IE2 ; 6SS4 ; 4IXU ; 4IE3 ; 4HZE ; 4I06 ; 6SS6
Drugbank	DB00125 ; DB00129 ; DB03731
KEGG	hsa:384

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Name: Pyroglutamic Acid

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0004	Huo Xiang	藿香	Patchouli	Pogostemon cablin
H0173	Lu Hui	芦荟	Kulaso aloe dried juice	Aloe vera
H0572	Tu Huo Xiang	土藿香	Patchouli	Pogostemon cablin
H0396	Sang Ye	桑叶	White mulberry leaf	Morus alba
H0391	Sang Pi	桑皮	Prepared root-bark white mulberry	Morus alba
H0339	Qing Dai	青黛	Natural indigo	Indigo naturalis
H0397	Sang Zhi	桑枝	White mulberry branch	Morus alba
H0005	Huo Xiang Ye	藿香叶	Patchouli	Pogostemon cablin
H1010	Du Huo Xiang	杜藿香	Patchouli	Pogostemon cablin
H1120	Guang Huo Xiang	广藿香	Patchouli	Pogostemon cablin