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Target Description
Type
Detail
Target ID
T74ZEH
Protein Name
Lysine-specific demethylase 2A
Uniprot ID
Q9Y2K7
Protein Name Alias
EC 1.14.11.27; CXXC-type zinc finger protein 8; F-box and leucine-rich repeat protein 11; F-box protein FBL7; F-box protein Lilina; F-box/LRR-repeat protein 11; JmjC domain-containing histone demethylation protein 1A
Gene ID
22992
Gene Symbol
KDM2A
Gene Alias
CXXC8; FBL11; FBL7; FBXL11; JHDM1A; KIAA1004
TTD
T71949: Research target
Pfam
PF00646
;
PF02008
;
PF16866
;
PF17811
GO
0032452:histone demethylase activity
0008270:zinc ion binding
0032922:circadian regulation of gene expression
0070544:histone H3-K36 demethylation
0006357:regulation of transcription by RNA polymerase II
0045322:unmethylated CpG binding
0003712:transcription coregulator activity
0006303:double-strand break repair via nonhomologous end joining
0010944:negative regulation of transcription by competitive promoter binding
0006482:protein demethylation
0051864:histone demethylase activity (H3-K36 specific)
0005654:nucleoplasm
0042752:regulation of circadian rhythm
PDB
2YU1
;
6C16
;
6BYH
;
2YU2
;
4BBQ
Drugbank
NA
KEGG
hsa:22992
Related Compounds (Total: 1)
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C1281
Name: Daminozide
Related Herbs (Total: 2)
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Herb id
Chinese Pin Yin
Chinese Character
English Name
Latin Name
H1161
Hang Ju
杭菊
Chrysanthemum flower
Chrysanthemum morifolium
H0092
Ju Hua
菊花
Florists chrysanthemum flower
Chrysanthemum morifolium