HIT-result

Type	Detail
Target ID	T77BI5
Protein Name	Target of rapamycin complex 2 subunit MAPKAP1
Uniprot ID	Q9BPZ7
Protein Name Alias	TORC2 subunit MAPKAP1; Mitogen-activated protein kinase 2-associated protein 1; Stress-activated map kinase-interacting protein 1; SAPK-interacting protein 1; mSIN1
Gene ID	79109
Gene Symbol	MAPKAP1
Gene Alias	MIP1; SIN1
TTD	T85544: Clinical Trial target
Pfam	PF16979 ; PF16978 ; PF05422
GO	0031932:TORC2 complex 1901796:regulation of signal transduction by p53 class mediator 0080025:phosphatidylinositol-3,5-bisphosphate binding 0032148:activation of protein kinase B activity 0046580:negative regulation of Ras protein signal transduction 0033138:positive regulation of peptidyl-serine phosphorylation 0043325:phosphatidylinositol-3,4-bisphosphate binding 0019901:protein kinase binding 0005886:plasma membrane 0005737:cytoplasm 0031410:cytoplasmic vesicle 0005547:phosphatidylinositol-3,4,5-trisphosphate binding 0005654:nucleoplasm 0031267:small GTPase binding 0070300:phosphatidic acid binding 0005794:Golgi apparatus 0030950:establishment or maintenance of actin cytoskeleton polarity 1900407:regulation of cellular response to oxidative stress 0005546:phosphatidylinositol-4,5-bisphosphate binding 0005829:cytosol 0038203:TORC2 signaling 0021762:substantia nigra development
PDB	5ZCS ; 6ZWO ; 3VOQ ; 6ZWM
Drugbank	NA
KEGG	hsa:79109

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0154	Ai Ye You	艾叶油	Argy wormwood leaf	Artemisia argyi
H0729	Ye Ju Hua	野菊花	Indian wild chrysanthemum flower	Chrysanthemum indicum
H0073	Jing Jie Sui	荆芥穗	NA	Schizonepetae spica
H0604	Wu Wei Teng	五味藤	NA	Securidaca inappendiculata
H0613	Wu Yue Ai	五月艾	Artemisia	Artemisia princeps
H0103	Ai Ye	艾叶	Argy wormwood leaf	Artemisia argyi
H0088	Ju He	橘核	Tangerine seed	Citrus reticulata
H0093	Ju Pi	橘皮	Tangerine pericarp	Citrus reticulata

Target Description