HIT-result

Type	Detail
Target ID	T77SWL
Protein Name	Serpin B3
Uniprot ID	P29508
Protein Name Alias	Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1
Gene ID	6317
Gene Symbol	SERPINB3
Gene Alias	SCCA; SCCA1
TTD	T45034: Research target
Pfam	PF00079
GO	0005634:nucleus 0070062:extracellular exosome 0010950:positive regulation of endopeptidase activity 0030335:positive regulation of cell migration 0010951:negative regulation of endopeptidase activity 0043086:negative regulation of catalytic activity 0035425:autocrine signaling 0008284:positive regulation of cell population proliferation 0035578:azurophil granule lumen 0031410:cytoplasmic vesicle 0005737:cytoplasm 0005615:extracellular space 0004867:serine-type endopeptidase inhibitor activity 0004869:cysteine-type endopeptidase inhibitor activity 0010466:negative regulation of peptidase activity 0031982:vesicle 0002020:protease binding 0043312:neutrophil degranulation 0038001:paracrine signaling 0010718:positive regulation of epithelial to mesenchymal transition 0005576:extracellular region 0045861:negative regulation of proteolysis 0001618:virus receptor activity 0043508:negative regulation of JUN kinase activity
PDB	4ZK0 ; 4ZK3 ; 2ZV6
Drugbank	DB04522 ; DB03929
KEGG	hsa:6317

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0151	Ling Yang Jiao	羚羊角	Antelope horn	Cornu saigae tataricae
H1110	Gua Lou Zi	瓜蒌子	mongolian snakegourd seed	Trichosanthes kirilowii maxim
H1152	Bai Jie Zi	白芥子	White mustard seed	Sinapis alba
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0043	Jie Zi	芥子	India mustard seed	Brassica juncea
H1167	He Tao	核桃	English walnut seed	Semen juglandis
H1168	He Tao Ren	核桃仁	English walnut seed	Semen juglandis
H0484	Shui Fei Ji	水飞蓟	St marys	Silybum marianum
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens

Target Description