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Target Description
Type
Detail
Target ID
T77W8L
Protein Name
Ribosomal protein S6 kinase alpha-1
Uniprot ID
Q15418
Protein Name Alias
S6K-alpha-1; EC 2.7.11.1; 90 kDa ribosomal protein S6 kinase 1; p90-RSK 1; p90RSK1; p90S6K; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK-1a; Ribosomal S6 kinase 1; RSK-1
Gene ID
6195
Gene Symbol
RPS6KA1
Gene Alias
MAPKAPK1A; RSK1
TTD
T83202: Patented target
Pfam
PF00069
;
PF00433
GO
0004674:protein serine/threonine kinase activity
0035556:intracellular signal transduction
0045597:positive regulation of cell differentiation
0005524:ATP binding
0043066:negative regulation of apoptotic process
0007268:chemical synaptic transmission
0106311:protein threonine kinase activity
0018105:peptidyl-serine phosphorylation
0005829:cytosol
0043154:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0043555:regulation of translation in response to stress
0030307:positive regulation of cell growth
0000287:magnesium ion binding
0005737:cytoplasm
0005654:nucleoplasm
0004711:ribosomal protein S6 kinase activity
0045893:positive regulation of transcription, DNA-templated
0043027:cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0072574:hepatocyte proliferation
0007049:cell cycle
0045944:positive regulation of transcription by RNA polymerase II
0043620:regulation of DNA-templated transcription in response to stress
0004712:protein serine/threonine/tyrosine kinase activity
0106310:protein serine kinase activity
0007165:signal transduction
2000491:positive regulation of hepatic stellate cell activation
PDB
5CSN
;
4NIF
;
2Z7R
;
5N7D
;
5CSJ
;
5N7F
;
2WNT
;
2Z7Q
;
2Z7S
;
3TEI
;
5CSI
;
5N7G
;
5V62
;
3RNY
;
4H3P
;
5V61
;
5CSF
;
6TWY
Drugbank
DB04751
;
DB12010
KEGG
hsa:6195
Related Compounds (Total: 1)
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C0355
Name: Quetiapine
Related Herbs (Total: 2)
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Herb id
Chinese Pin Yin
Chinese Character
English Name
Latin Name
H0847
Zi He Che
紫河车
Human placenta
Homo sapiens
H0360
Ren Zhong Bai
人中白
Human urine sediment
Homo sapiens