HIT-result

Type	Detail
Target ID	T81ILO
Protein Name	Fibrinogen beta chain
Uniprot ID	P02675
Protein Name Alias	NA
Gene ID	2244
Gene Symbol	FGB
Gene Alias	NA
TTD	T19414: Successful target
Pfam	PF00147 ; PF08702
GO	0042730:fibrinolysis 0070062:extracellular exosome 0007155:cell adhesion 0071347:cellular response to interleukin-1 0031091:platelet alpha granule 0062023:collagen-containing extracellular matrix 0002250:adaptive immune response 0050714:positive regulation of protein secretion 0005938:cell cortex 2000352:negative regulation of endothelial cell apoptotic process 0009986:cell surface 0007160:cell-matrix adhesion 0045907:positive regulation of vasoconstriction 0005201:extracellular matrix structural constituent 0051592:response to calcium ion 0002224:toll-like receptor signaling pathway 0005615:extracellular space 0034622:cellular protein-containing complex assembly 0030198:extracellular matrix organization 0031093:platelet alpha granule lumen 0043152:induction of bacterial agglutination 0034116:positive regulation of heterotypic cell-cell adhesion 0072378:blood coagulation, fibrin clot formation 0005783:endoplasmic reticulum 0005886:plasma membrane 0005198:structural molecule activity 0007596:blood coagulation 1902042:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 0005577:fibrinogen complex 0051087:chaperone binding 0045921:positive regulation of exocytosis 0045202:synapse 0070374:positive regulation of ERK1 and ERK2 cascade 0070527:platelet aggregation 0051258:protein polymerization 0031639:plasminogen activation 0005576:extracellular region 1903561:extracellular vesicle 0072562:blood microparticle 0005102:signaling receptor binding 0090277:positive regulation of peptide hormone secretion 1900026:positive regulation of substrate adhesion-dependent cell spreading 0009897:external side of plasma membrane 0044320:cellular response to leptin stimulus 0002576:platelet degranulation 0045087:innate immune response
PDB	3E1I ; 2XNY ; 1FZC ; 2OYI ; 3BVH ; 1N86 ; 3HUS ; 2A45 ; 1FZE ; 1FZA ; 2Z4E ; 1RE4 ; 2Q9I ; 3H32 ; 2HOD ; 1LT9 ; 2FFD ; 6BIL ; 2HLO ; 1RF0 ; 1RF1 ; 1LTJ ; 2HPC ; 2OYH ; 6ATZ ; 1N8E ; 2H43 ; 1FZF ; 1RE3 ; 1FZB ; 1FZG ; 2XNX ; 6BIJ ; 3GHG
Drugbank	DB13151 ; DB11572 ; DB04919 ; DB11311 ; DB11300 ; DB11571 ; DB00364
KEGG	hsa:2244

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Name: Tranexamic Acid

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0847	Zi He Che	紫河车	Human placenta	Homo sapiens
H0360	Ren Zhong Bai	人中白	Human urine sediment	Homo sapiens