Target Description

Type Detail
Target ID T87N55
Protein Name Proteasome subunit beta type-6
Uniprot ID P28072
Protein Name Alias EC 3.4.25.1;  Macropain delta chain;  Multicatalytic endopeptidase complex delta chain;  Proteasome delta chain;  Proteasome subunit Y
Gene ID 5694
Gene Symbol PSMB6
Gene Alias LMPY;  Y
TTD T54973: Patented target
Pfam PF00227
GO
0060071:Wnt signaling pathway, planar cell polarity pathway

0005634:nucleus

0043488:regulation of mRNA stability

0002479:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

0070062:extracellular exosome

1902036:regulation of hematopoietic stem cell differentiation

0070498:interleukin-1-mediated signaling pathway

1901990:regulation of mitotic cell cycle phase transition

0005829:cytosol

0005839:proteasome core complex

0019774:proteasome core complex, beta-subunit complex

0004298:threonine-type endopeptidase activity

0036388:pre-replicative complex assembly

0006521:regulation of cellular amino acid metabolic process

0002223:stimulatory C-type lectin receptor signaling pathway

0010972:negative regulation of G2/M transition of mitotic cell cycle

0050852:T cell receptor signaling pathway

0043161:proteasome-mediated ubiquitin-dependent protein catabolic process

0000165:MAPK cascade

0038095:Fc-epsilon receptor signaling pathway

0010499:proteasomal ubiquitin-independent protein catabolic process

0031145:anaphase-promoting complex-dependent catabolic process

0061418:regulation of transcription from RNA polymerase II promoter in response to hypoxia

0038061:NIK/NF-kappaB signaling

0055085:transmembrane transport

0000209:protein polyubiquitination

0031146:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

0005737:cytoplasm

0016032:viral process

0090090:negative regulation of canonical Wnt signaling pathway

0045296:cadherin binding

0033209:tumor necrosis factor-mediated signaling pathway

0005654:nucleoplasm

0016579:protein deubiquitination

0090263:positive regulation of canonical Wnt signaling pathway

0043687:post-translational protein modification

0004175:endopeptidase activity

0000502:proteasome complex

PDB 5VFT ; 5LN3 ; 5T0H ; 5VFO ; 5GJR ; 5LEZ ; 5T0G ; 6MSK ; 6MSH ; 5VFS ; 5LF7 ; 6MSG ; 6KWY ; 5T0I ; 5VFR ; 6REY ; 6XMJ ; 6WJD ; 5LF0 ; 5L4G ; 6RGQ ; 5LF6 ; 5LF3 ; 4R67 ; 5LF1 ; 5VFQ ; 5LE5 ; 6MSD ; 6MSE ; 6R70 ; 5LF4 ; 6MSB ; 5M32 ; 5VFP ; 6WJN ; 5LEX ; 4R3O ; 5LEY ; 5T0C ; 5A0Q ; 6MSJ ; 5GJQ ; 5T0J ; 5VFU
Drugbank DB08515
KEGG hsa:5694

Related Compounds  (Total: 2)

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C0737
Name: Abscisic Acid
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C0843
Name: Abscisic Acid


Related Herbs  (Total: 9)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0417 Shan Yao山药 Common yamDioscorea batatas
H0530 Tao Ren Shuang桃仁霜 Peach kernelPrunus persica
H0354 Ren Dong Teng忍冬藤 Japanese honeysuckle vineLonicera japonica
H0064 Jin Yin Hua金银花 Japanese honeysuckleLonicera japonica
H0215 Mai Ya麦芽 Barley germinating fruitHordeum vulgare
H0527 Tao PeachPrunus persica
H0065 Jin Yin Hua Ti Qu Ye金银花提取液 Japanese honeysuckleLonicera japonica
H0531 Tao Zhi桃枝 Peach juvenile branchPrunus persica
H0529 Tao Ren桃仁 Peach kernelPrunus persica