Target Description
| Type | Detail |
|---|---|
| Target ID | T88D60 |
| Protein Name | Thrombopoietin receptor |
| Uniprot ID |
P40238 |
| Protein Name Alias | TPO-R; Myeloproliferative leukemia protein; Proto-oncogene c-Mpl; CD antigen CD110 |
| Gene ID |
4352 |
| Gene Symbol | MPL |
| Gene Alias | TPOR |
| TTD | T16156: Successful target |
| Pfam | PF00041 ; PF09067 |
| GO |
0038164:thrombopoietin receptor activity
0001780:neutrophil homeostasis 0016021:integral component of membrane 0031965:nuclear membrane 1990959:eosinophil homeostasis 0050671:positive regulation of lymphocyte proliferation 0035702:monocyte homeostasis 0043025:neuronal cell body 1905221:positive regulation of platelet formation 0071456:cellular response to hypoxia 0070527:platelet aggregation 0005886:plasma membrane 0009986:cell surface 0043005:neuron projection 1990960:basophil homeostasis 0005794:Golgi apparatus |
| PDB | NA |
| Drugbank | DB05930 ; DB11995 ; DB06210 ; DB06534 ; DB13125 ; DB05332 |
| KEGG | hsa:4352 |
