HIT-result

Type	Detail
Target ID	T88KDE
Protein Name	Homeobox protein Nkx-2.1
Uniprot ID	P43699
Protein Name Alias	Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1; Thyroid-specific enhancer-binding protein; T/EBP
Gene ID	7080
Gene Symbol	NKX2-1
Gene Alias	NKX2A; TITF1; TTF1
TTD	NA
Pfam	PF00046
GO	0005667:transcription regulator complex 0042753:positive regulation of circadian rhythm 0000976:transcription regulatory region sequence-specific DNA binding 0048511:rhythmic process 0021892:cerebral cortex GABAergic interneuron differentiation 0007626:locomotory behavior 0021795:cerebral cortex cell migration 0048646:anatomical structure formation involved in morphogenesis 0008134:transcription factor binding 0060441:epithelial tube branching involved in lung morphogenesis 0007420:brain development 0060510:type II pneumocyte differentiation 0030336:negative regulation of cell migration 0033327:Leydig cell differentiation 0030512:negative regulation of transforming growth factor beta receptor signaling pathway 0021877:forebrain neuron fate commitment 0009725:response to hormone 0000977:RNA polymerase II transcription regulatory region sequence-specific DNA binding 0021759:globus pallidus development 0031128:developmental induction 0030154:cell differentiation 0001764:neuron migration 0030900:forebrain development 0021766:hippocampus development 0021798:forebrain dorsal/ventral pattern formation 0006644:phospholipid metabolic process 0005654:nucleoplasm 0019899:enzyme binding 0030324:lung development 0003677:DNA binding 0045893:positive regulation of transcription, DNA-templated 0030878:thyroid gland development 0021983:pituitary gland development 0000785:chromatin 0003700:DNA-binding transcription factor activity 0045944:positive regulation of transcription by RNA polymerase II 0048709:oligodendrocyte differentiation 0005634:nucleus 0000978:RNA polymerase II cis-regulatory region sequence-specific DNA binding 0007411:axon guidance 0010628:positive regulation of gene expression 0045892:negative regulation of transcription, DNA-templated 0060430:lung saccule development 0006357:regulation of transcription by RNA polymerase II 0060486:club cell differentiation 0000122:negative regulation of transcription by RNA polymerase II 0000981:DNA-binding transcription factor activity, RNA polymerase II-specific 0010719:negative regulation of epithelial to mesenchymal transition 0007492:endoderm development 0001161:intronic transcription regulatory region sequence-specific DNA binding
PDB	NA
Drugbank	NA
KEGG	hsa:7080

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Name: thyroglobulin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name