HIT-result

Type	Detail
Target ID	T93L35
Protein Name	Muscarinic acetylcholine receptor M1
Uniprot ID	P11229
Protein Name Alias	NA
Gene ID	1128
Gene Symbol	CHRM1
Gene Alias	NA
TTD	T28893: Successful target
Pfam	PF00001
GO	0040012:regulation of locomotion 0007399:nervous system development 0043270:positive regulation of ion transport 0007205:protein kinase C-activating G protein-coupled receptor signaling pathway 0007274:neuromuscular synaptic transmission 0007187:G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 0090316:positive regulation of intracellular protein transport 0030425:dendrite 0007268:chemical synaptic transmission 0016020:membrane 0099061:integral component of postsynaptic density membrane 0050890:cognition 0007186:G protein-coupled receptor signaling pathway 0007213:G protein-coupled acetylcholine receptor signaling pathway 0046541:saliva secretion 0016907:G protein-coupled acetylcholine receptor activity 0099529:neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 0004993:G protein-coupled serotonin receptor activity 0060251:regulation of glial cell proliferation 0043679:axon terminus 0045202:synapse 0098685:Schaffer collateral - CA1 synapse 0098981:cholinergic synapse 0005886:plasma membrane 0007197:adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway 0030594:neurotransmitter receptor activity 0098978:glutamatergic synapse 0005887:integral component of plasma membrane 0007207:phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway 0004435:phosphatidylinositol phospholipase C activity 0099056:integral component of presynaptic membrane 0007165:signal transduction
PDB	5CXV ; 6WJC ; 6OIJ
Drugbank	DB09194 ; DB00209 ; DB00458 ; DB00185 ; DB00782 ; DB01019 ; DB01409 ; DB00767 ; DB00725 ; DB05752 ; DB00572 ; DB00408 ; DB08897 ; DB00354 ; DB00986 ; DB04843 ; DB00321 ; DB00387 ; DB00411 ; DB00979 ; DB00805 ; DB00875 ; DB00940 ; DB06702 ; DB01591 ; DB00777 ; DB05766 ; DB00934 ; DB01069 ; DB09167 ; DB01239 ; DB11156 ; DB11235 ; DB00462 ; DB00508 ; DB00622 ; DB00810 ; DB00907 ; DB00747 ; DB00483 ; DB01221 ; DB02010 ; DB00809 ; DB09076 ; DB01231 ; DB00219 ; DB06153 ; DB05152 ; DB01233 ; DB00420 ; DB01148 ; DB01618 ; DB00543 ; DB04365 ; DB09262 ; DB00363 ; DB00505 ; DB12278 ; DB00568 ; DB00540 ; DB00670 ; DB01062 ; DB03128 ; DB13581 ; DB00424 ; DB01403 ; DB00715 ; DB00245 ; DB00434 ; DB01238 ; DB00771 ; DB01175 ; DB01036 ; DB00383 ; DB00366 ; DB00804 ; DB00280 ; DB09089 ; DB11855 ; DB00193 ; DB00477 ; DB06787 ; DB00332 ; DB00392 ; DB01151 ; DB00376 ; DB01142 ; DB14185 ; DB00202 ; DB00726 ; DB00340 ; DB00334 ; DB11181 ; DB00517 ; DB00496 ; DB01085 ; DB01224 ; DB00454 ; DB00942 ; DB00246 ; DB00835 ; DB00342
KEGG	hsa:1128

Target Description

Related Compounds (Total: 1)

Related Herbs (Total: 1)