HIT-result

Target Description

Type	Detail
Target ID	T95CAO
Protein Name	Monoglyceride lipase
Uniprot ID	Q99685
Protein Name Alias	MGL; EC 3.1.1.23; HU-K5; Lysophospholipase homolog; Lysophospholipase-like; Monoacylglycerol lipase; MAGL
Gene ID	11343
Gene Symbol	MGLL
Gene Alias	NA
TTD	T18664: Clinical Trial target
Pfam	PF12146
GO	0019433:triglyceride catabolic process 0050727:regulation of inflammatory response 0046464:acylglycerol catabolic process 0005829:cytosol 0009966:regulation of signal transduction 0006954:inflammatory response 0052651:monoacylglycerol catabolic process 0005654:nucleoplasm 0016298:lipase activity 0004622:lysophospholipase activity 2000124:regulation of endocannabinoid signaling pathway 0016020:membrane 0006629:lipid metabolic process 0005886:plasma membrane 0006633:fatty acid biosynthetic process 0019898:extrinsic component of membrane 0047372:acylglycerol lipase activity 0042803:protein homodimerization activity 0019369:arachidonic acid metabolic process 0036155:acylglycerol acyl-chain remodeling 0005789:endoplasmic reticulum membrane 0051930:regulation of sensory perception of pain
PDB	6BQ0 ; 4UUQ ; 5ZUN ; 6AX1 ; 3JW8 ; 3PE6 ; 3JWE ; 3HJU
Drugbank	NA
KEGG	hsa:11343

Type

Detail

Target ID

T95CAO

Protein Name

Monoglyceride lipase

Uniprot ID

Q99685

Protein Name Alias

MGL; EC 3.1.1.23; HU-K5; Lysophospholipase homolog; Lysophospholipase-like; Monoacylglycerol lipase; MAGL

Gene ID

11343

Gene Symbol

MGLL

Gene Alias

TTD

T18664: Clinical Trial target

Pfam

PF12146

0019433:triglyceride catabolic process

0050727:regulation of inflammatory response

0046464:acylglycerol catabolic process

0005829:cytosol

0009966:regulation of signal transduction

0006954:inflammatory response

0052651:monoacylglycerol catabolic process

0005654:nucleoplasm

0016298:lipase activity

0004622:lysophospholipase activity

2000124:regulation of endocannabinoid signaling pathway

0016020:membrane

0006629:lipid metabolic process

0005886:plasma membrane

0006633:fatty acid biosynthetic process

0019898:extrinsic component of membrane

0047372:acylglycerol lipase activity

0042803:protein homodimerization activity

0019369:arachidonic acid metabolic process

0036155:acylglycerol acyl-chain remodeling

0005789:endoplasmic reticulum membrane

0051930:regulation of sensory perception of pain

PDB

6BQ0 ; 4UUQ ; 5ZUN ; 6AX1 ; 3JW8 ; 3PE6 ; 3JWE ; 3HJU

Drugbank

KEGG

hsa:11343

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0353	Que Mei Teng Gen	雀梅藤根	Hedge sageretia	Sageretia thea
H0987	Bai Bu Jin Gao	百部浸膏	Tuber stemona	Stemona tuberosa
H1207	Hu Ma	胡麻	white seed of oriental sesame	Sesamum indicum
H1208	Hu Ma Ren	胡麻仁	white seed of oriental sesame	Sesamum indicum
H0977	Bai Bu	百部	Tuber stemona	Stemona tuberosa
H0738	Yi Xing Nan Wu Wei Zi	异型南五味子	Curious kadsura	Kadsura heteroclita
H0982	Bai Bu Gan Gao	百部干膏	Tuber stemona	Stemona tuberosa
H0991	Bai Bu Liu Jin Gao	百部流浸膏	Tuber stemona	Stemona tuberosa
H1181	Hei Zhi Ma	黑芝麻	Oriental sesame	Sesamum indicum

Target Description

Related Compounds (Total: 2)

Related Herbs (Total: 9)