HIT-result

Type	Detail
Target ID	T95K0S
Protein Name	2-5A-dependent ribonuclease
Uniprot ID	Q05823
Protein Name Alias	2-5A-dependent RNase; EC 3.1.26.-; Ribonuclease 4; Ribonuclease L; RNase L
Gene ID	6041
Gene Symbol	RNASEL
Gene Alias	RNS4
TTD	T25200: Research target
Pfam	PF00069 ; PF12796 ; PF06479
GO	0005524:ATP binding 0043021:ribonucleoprotein complex binding 0051607:defense response to virus 0006468:protein phosphorylation 0060338:regulation of type I interferon-mediated signaling pathway 0006397:mRNA processing 0019843:rRNA binding 0004540:ribonuclease activity 0005829:cytosol 0046872:metal ion binding 0045444:fat cell differentiation 0042802:identical protein binding 0006396:RNA processing 0006364:rRNA processing 0004521:endoribonuclease activity 0003723:RNA binding 0045944:positive regulation of transcription by RNA polymerase II 0004672:protein kinase activity 0016363:nuclear matrix 0005759:mitochondrial matrix 0046326:positive regulation of glucose import 0045071:negative regulation of viral genome replication 0060337:type I interferon signaling pathway 0043488:regulation of mRNA stability
PDB	4G8K ; 4OAV ; 4G8L ; 4OAU ; 1WDY
Drugbank	NA
KEGG	hsa:6041

Target Description