HIT-result

Type	Detail
Target ID	T96NMT
Protein Name	Serine/threonine-protein kinase PINK1, mitochondrial
Uniprot ID	Q9BXM7
Protein Name Alias	EC 2.7.11.1; BRPK; PTEN-induced putative kinase protein 1
Gene ID	65018
Gene Symbol	PINK1
Gene Alias	NA
TTD	NA
Pfam	PF00069
GO	0035556:intracellular signal transduction 0004672:protein kinase activity 0043422:protein kinase B binding 0046329:negative regulation of JNK cascade 0106310:protein serine kinase activity 0002931:response to ischemia 0004674:protein serine/threonine kinase activity 0016236:macroautophagy 0034599:cellular response to oxidative stress 1902803:regulation of synaptic vesicle transport 0097413:Lewy body 0018105:peptidyl-serine phosphorylation 0090200:positive regulation of release of cytochrome c from mitochondria 0005783:endoplasmic reticulum 0031398:positive regulation of protein ubiquitination 0010629:negative regulation of gene expression 1903298:negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway 1903955:positive regulation of protein targeting to mitochondrion 1903751:negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide 0006979:response to oxidative stress 0098779:positive regulation of mitophagy in response to mitochondrial depolarization 0030424:axon 0007005:mitochondrion organization 0033603:positive regulation of dopamine secretion 0043254:regulation of protein-containing complex assembly 0038203:TORC2 signaling 0042981:regulation of apoptotic process 0005829:cytosol 0071456:cellular response to hypoxia 0051443:positive regulation of ubiquitin-protein transferase activity 0031307:integral component of mitochondrial outer membrane 0051897:positive regulation of protein kinase B signaling 0032148:activation of protein kinase B activity 0090141:positive regulation of mitochondrial fission 0005737:cytoplasm 1902958:positive regulation of mitochondrial electron transport, NADH to ubiquinone 0006511:ubiquitin-dependent protein catabolic process 0045727:positive regulation of translation 1902902:negative regulation of autophagosome assembly 0005524:ATP binding 0001934:positive regulation of protein phosphorylation 0048471:perinuclear region of cytoplasm 1900407:regulation of cellular response to oxidative stress 0002020:protease binding 0000422:autophagy of mitochondrion 0010310:regulation of hydrogen peroxide metabolic process 0050821:protein stabilization 0006468:protein phosphorylation 0051091:positive regulation of DNA-binding transcription factor activity 0005739:mitochondrion 0005743:mitochondrial inner membrane 0061136:regulation of proteasomal protein catabolic process 0033138:positive regulation of peptidyl-serine phosphorylation 0016504:peptidase activator activity 0051881:regulation of mitochondrial membrane potential 0030426:growth cone 0005634:nucleus 0043524:negative regulation of neuron apoptotic process 0055131:C3HC4-type RING finger domain binding 0072656:maintenance of protein location in mitochondrion 2001243:negative regulation of intrinsic apoptotic signaling pathway 0097237:cellular response to toxic substance 0036289:peptidyl-serine autophosphorylation 0106311:protein threonine kinase activity 0016242:negative regulation of macroautophagy 0031625:ubiquitin protein ligase binding 1901727:positive regulation of histone deacetylase activity 0016301:kinase activity 1904841:TORC2 complex binding 1903146:regulation of autophagy of mitochondrion 0044877:protein-containing complex binding 1904881:cellular response to hydrogen sulfide 1903147:negative regulation of autophagy of mitochondrion 0097449:astrocyte projection 0005741:mitochondrial outer membrane 0002082:regulation of oxidative phosphorylation 0005856:cytoskeleton 0016020:membrane 1903204:negative regulation of oxidative stress-induced neuron death 0043123:positive regulation of I-kappaB kinase/NF-kappaB signaling 0099074:mitochondrion to lysosome transport 1903214:regulation of protein targeting to mitochondrion 0010857:calcium-dependent protein kinase activity 0010952:positive regulation of peptidase activity 0016567:protein ubiquitination 0035307:positive regulation of protein dephosphorylation 2000378:negative regulation of reactive oxygen species metabolic process 0032226:positive regulation of synaptic transmission, dopaminergic 1904544:positive regulation of free ubiquitin chain polymerization 1903384:negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway 2000377:regulation of reactive oxygen species metabolic process 0031396:regulation of protein ubiquitination 1903852:positive regulation of cristae formation 0044297:cell body 0000287:magnesium ion binding 0000785:chromatin 0072655:establishment of protein localization to mitochondrion 2001171:positive regulation of ATP biosynthetic process 0022904:respiratory electron transport chain 0005758:mitochondrial intermembrane space 1903202:negative regulation of oxidative stress-induced cell death 0010821:regulation of mitochondrion organization 0016239:positive regulation of macroautophagy 1904783:positive regulation of NMDA glutamate receptor activity 0090258:negative regulation of mitochondrial fission
PDB	NA
Drugbank	NA
KEGG	hsa:65018

Go to browser

Name: Kinetin

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0137	Ban Lan Gen	板蓝根	Indigowoad root	Isatis indigotica
H0937	Da Qing Ye	大青叶	Indigo-coloured woad leaf	Isatis indigotica
H0263	Mu Ban Lan Gen	木板蓝根	Indigowoad root	Isatis indigotica
H0265	Mu Da Qing Ye	木大青叶	Indigo-coloured woad leaf equivalent	Isatis indigotica
H0131	Ban Lan	板蓝	Indigowoad root	Isatis indigotica