Target Description

Type Detail
Target ID T99T1V
Protein Name Prostaglandin E synthase 3
Uniprot ID Q15185
Protein Name Alias EC 5.3.99.3;  Cytosolic prostaglandin E2 synthase;  cPGES;  Hsp90 co-chaperone;  Progesterone receptor complex p23;  Telomerase-binding protein p23
Gene ID 10728
Gene Symbol PTGES3
Gene Alias P23;  TEBP
TTD NA
Pfam PF04969
GO
1900034:regulation of cellular response to heat

0000723:telomere maintenance

0051879:Hsp90 protein binding

0006805:xenobiotic metabolic process

1905323:telomerase holoenzyme complex assembly

0051973:positive regulation of telomerase activity

0007004:telomere maintenance via telomerase

0101031:chaperone complex

0051082:unfolded protein binding

0005654:nucleoplasm

0070182:DNA polymerase binding

0005829:cytosol

0051085:chaperone cofactor-dependent protein refolding

0032991:protein-containing complex

0001516:prostaglandin biosynthetic process

0005697:telomerase holoenzyme complex

0003720:telomerase activity

0000781:chromosome, telomeric region

0019371:cyclooxygenase pathway

0005634:nucleus

0051087:chaperone binding

0007165:signal transduction

0051131:chaperone-mediated protein complex assembly

0006457:protein folding

0050821:protein stabilization

0050220:prostaglandin-E synthase activity

0042327:positive regulation of phosphorylation

PDB 1LG0 ; 1EJF
Drugbank DB05036 ; DB09130 ; DB00316
KEGG hsa:10728

Related Compounds  (Total: 2)

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C0099
Name: Gedunin
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C0545
Name: Ailanthone


Related Herbs  (Total: 5)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0108 Ku Lian Pi苦楝皮 Chinaberry-tree barkMelia azedarach
H0109 Ku Lian Zi苦楝子 NAMelia azedarach
H0902 Chun Pi椿皮 Ailanthus bark, tree of heaven barkAilanthi cortex
H0900 Chun Gen Pi椿根皮 Ailanthus bark, tree of heaven barkAilanthus altissima
H0897 Chuan Lian川楝 ChinaberryMelia azedarach