HIT-result

ID: C0036	Common name: Duvoglustat
IUPAC: (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol	CAS: CAS:19130-96-2
Chembl ID: CHEMBL307429	Pubchem ID: CID:29435
Formula: C6H13NO4	TCM-ID: TCMC1090
Smiles: OC[C@H]1NC[C@@H]([C@H]([C@@H]1O)O)O
Alias: 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, [2R-(2α,3β,4α,5β)]-; Glucopyranose, 5-amino-1,5-dideoxy-, D-; (2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol; 1,5-Dideoxy-1,5-imino-D-glucitol; 1-Deoxynojirimycin; 5-Amino-1,5-dideoxy-D-glucopyranose; BAY-h 5595; D-1-Deoxynojirimycin; D-Glucitol, 1,5-dideoxy-1,5-imino-; Deoxynojirimycin; Duvoglustat; Moranolin; Moranoline; Nojirimycin, 1-deoxy-	Structure:

Target id	Protein Name	Gene Symbol	Uniprot ID	Target Level	No.of Literature Evidence
T12PIB	Lysosomal alpha-glucosidase	GAA	P10253	A	3 Reference(s)
T09KMC	Solute carrier family 5 member 4	SLC5A4	Q9NY91	A	1 Reference(s)
T97K9N	Killer cell lectin-like receptor subfamily B member 1	KLRB1	Q12918	B	1 Reference(s)

*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0476	Can E	蚕蛾	Silkworm	Bombyx mori
H0490	Can Jian	蚕茧	Silk cocoon	Bombyx mori
H0495	Can Sha	蚕砂	Silkworm excrement	Bombyx mori
H0500	Can Yong	蚕蛹	Silkworm chrysalis	Bombyx mori
H1134	Bai Jiang Can	白僵蚕	Silkworm larva	Bombyx mori
H0396	Sang Ye	桑叶	White mulberry leaf	Morus alba
H0391	Sang Pi	桑皮	Prepared root-bark white mulberry	Morus alba
H0397	Sang Zhi	桑枝	White mulberry branch	Morus alba

Compound Description

Related Targets (Total: 3)

Related Herbs (Total: 8)