Compound Description
| ID: C0044 | Common name: Enoxolone |
| IUPAC: (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid | CAS: CAS:471-53-4 |
| Chembl ID: CHEMBL230006 | Pubchem ID: CID:10114 |
| Formula: C30H46O4 | TCM-ID: TCMC1111 |
| Smiles: O=C1C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@]2([C@]2([C@H]1[C@@]1(C)CC[C@@H](C([C@@H]1CC2)(C)C)O)C)C)C(=O)O | |
| Alias:
Olean-12-en-30-oic acid, 3β-hydroxy-11-oxo-;
Uralenic acid; (3β,20β)-3-Hydroxy-11-oxoolean-12-en-29-oic acid; 18β-Glycyrrhetic acid; 18β-Glycyrrhetinic acid; Arthrodont; Biosone; Enoxolone; GM 1658; Glycyrrhetic acid; Glycyrrhetin; Glycyrrhetinic acid; NSC 35347; PO 12; STX 352; Subglycyrrhelinic acid; α-Glycyrrhetinic acid |
Structure:
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Related Targets (Total: 3)
| Target id | Protein Name | Gene Symbol | Uniprot ID | Target Level | No.of Literature Evidence |
|---|---|---|---|---|---|
| T92E71 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | HSD11B2 |
P80365 |
A | 4 Reference(s) |
| T40DIM | Corticosteroid 11-beta-dehydrogenase isozyme 1 | HSD11B1 |
P28845 |
A | 1 Reference(s) |
| T47H3O | Heat shock protein HSP 90-alpha | HSP90AA1 |
P07900 |
A | 1 Reference(s) |
*In this table, target level represents the quality confidence indicators of targets.
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Level 'A' represents "Directly inhibit/activate".
Level 'B' represents "Indirectly inhibit/ activate", "Enzyme substate" and "Enzyme product".
Level 'C' represents "Up/Down regulation" and "Others".
Related Herbs (Total: 15)
| Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
|---|---|---|---|---|
| H1067 | Gan Cao Fen | 甘草粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0444 | Sheng Gan Cao | 生甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1076 | Gan Cao Shao | 甘草梢 | tip of licorice root | Radix glycyrrhizae uralensis |
| H1075 | Gan Cao Liu Jin Gao | 甘草流浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0240 | Mi Gan Cao | 蜜甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
| H1066 | Gan Cao | 甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
| H0571 | Tu Gan Cao | 土甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1072 | Gan Cao Gao | 甘草膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1071 | Gan Cao Gan Jin Gao | 甘草干浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1073 | Gan Cao Jie | 甘草节 | Glycyrrhiza uralensis fisch | Glycyrrhiza uralensis |
| H1070 | Gan Cao Gan Gao Fen | 甘草干膏粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1074 | Gan Cao Jin Gao | 甘草浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
| H1069 | Gan Cao Gan Gao | 甘草干膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
Ckey description of the interaction between compound and target