Herb Description
| Herb ID: H1066 | Chinese Character: 甘草 |
| English Name: Glycyrrhiza inflata | Latin Name: Glycyrrhiza uralensis |
| Chinese Pin Yin : Gan Cao | TCM-ID: TCMH628 |
| Therapeutic Function in Chinese : 补虚 | Therapeutic Function in English: For tonifying weakness |
| Herb Function: Reinforce the function of the spleen and replenish qi, remove heat and counteract toxicity, dispel phlegm and relieve cough, alleviate spasmodic pain, and moderate drug actions | |
Related Targets (Total: 382)
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
|---|---|---|---|---|
| T48J1U | Aldo-keto reductase family 1 member C1 | AKR1C1 |
Q04828 |
3 Reference(s) |
| T76PKX | Mast/stem cell growth factor receptor Kit | KIT |
P10721 |
1 Reference(s) |
| T40DIM | Corticosteroid 11-beta-dehydrogenase isozyme 1 | HSD11B1 |
P28845 |
4 Reference(s) |
| T54VET | Protein tyrosine phosphatase type IVA 3 | PTP4A3 |
O75365 |
1 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
10 Reference(s) |
| T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
6 Reference(s) |
| T37ADS | Early growth response protein 1 | EGR1 |
P18146 |
1 Reference(s) |
| T96OOK | Signal transducer and activator of transcription 3 | STAT3 |
P40763 |
5 Reference(s) |
| T20JZ2 | Androgen receptor | AR |
P10275 |
7 Reference(s) |
| T12RJE | Casein kinase II subunit alpha' | CSNK2A2 |
P19784 |
1 Reference(s) |
| T47C6A | Phosphoglycerate mutase 1 | PGAM1 |
P18669 |
1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
16 Reference(s) |
| T29MD1 | Mitogen-activated protein kinase 8 | MAPK8 |
P45983 |
6 Reference(s) |
| T92HNO | High mobility group protein B1 | HMGB1 |
P09429 |
35 Reference(s) |
| T32JN2 | Beta-glucuronidase | GUSB |
P08236 |
1 Reference(s) |
| T16MRU | NACHT, LRR and PYD domains-containing protein 3 | NLRP3 |
Q96P20 |
2 Reference(s) |
| T75H3W | Cyclin-dependent kinase 2 | CDK2 |
P24941 |
6 Reference(s) |
| T77TY2 | Protein disulfide-isomerase | P4HB |
P07237 |
2 Reference(s) |
| T63BQU | Cytochrome P450 1A1 | CYP1A1 |
P04798 |
6 Reference(s) |
| T61J7T | Mothers against decapentaplegic homolog 2 | SMAD2 |
Q15796 |
1 Reference(s) |
| T78O6C | Mothers against decapentaplegic homolog 3 | SMAD3 |
P84022 |
3 Reference(s) |
| T88LSZ | Aromatase | CYP19A1 |
P11511 |
3 Reference(s) |
| T83SXS | 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 | HSD17B7 |
P56937 |
1 Reference(s) |
| T16UZ4 | Dipeptidyl peptidase 4 | DPP4 |
P27487 |
2 Reference(s) |
| T50V79 | Interleukin-4 | IL4 |
P05112 |
5 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
7 Reference(s) |
| T10ICM | Oxidized low-density lipoprotein receptor 1 | OLR1 |
P78380 |
1 Reference(s) |
| T48DAP | 40S ribosomal protein S9 | RPS9 |
P46781 |
1 Reference(s) |
| T82ALJ | Glycogen synthase kinase-3 beta | GSK3B |
P49841 |
3 Reference(s) |
| T42D4V | Histone deacetylase 1 | HDAC1 |
Q13547 |
1 Reference(s) |
| T64X48 | C-X-C chemokine receptor type 4 | CXCR4 |
P61073 |
2 Reference(s) |
| T86MX7 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | CD38 |
P28907 |
1 Reference(s) |
| T32R5L | Cyclin-dependent kinase 9 | CDK9 |
P50750 |
1 Reference(s) |
| T11BI7 | Toll-like receptor 4 | TLR4 |
O00206 |
4 Reference(s) |
| T42PUG | Solute carrier family 2, facilitated glucose transporter member 1 | SLC2A1 |
P11166 |
4 Reference(s) |
| T71BDH | Mitogen-activated protein kinase 14 | MAPK14 |
Q16539 |
6 Reference(s) |
| T68HNO | Glutathione S-transferase omega-1 | GSTO1 |
P78417 |
1 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
11 Reference(s) |
| T87AXU | ADP/ATP translocase 2 | SLC25A5 |
P05141 |
2 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
5 Reference(s) |
| T05RAA | Inhibitor of nuclear factor kappa-B kinase subunit alpha | CHUK |
O15111 |
1 Reference(s) |
| T55IBP | Zinc finger protein SNAI1 | SNAI1 |
O95863 |
1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
9 Reference(s) |
| T62USB | Tumor necrosis factor receptor superfamily member 10A | TNFRSF10A |
O00220 |
1 Reference(s) |
| T32PI2 | Programmed cell death 1 ligand 1 | CD274 |
Q9NZQ7 |
1 Reference(s) |
| T40XWM | Proto-oncogene tyrosine-protein kinase ROS | ROS1 |
P08922 |
1 Reference(s) |
| T92E71 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | HSD11B2 |
P80365 |
6 Reference(s) |
| T47H3O | Heat shock protein HSP 90-alpha | HSP90AA1 |
P07900 |
2 Reference(s) |
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
7 Reference(s) |
| T91W8B | All-trans-retinol dehydrogenase [NAD(+)] ADH4 | ADH4 |
P08319 |
1 Reference(s) |
| T03VS9 | Protein-tyrosine kinase 2-beta | PTK2B |
Q14289 |
3 Reference(s) |
| T44WZO | Alcohol dehydrogenase 1C | ADH1C |
P00326 |
1 Reference(s) |
| T12T4H | Brain-derived neurotrophic factor | BDNF |
P23560 |
1 Reference(s) |
| T50SX0 | Nuclear receptor subfamily 1 group I member 2 | NR1I2 |
O75469 |
3 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
30 Reference(s) |
| T63YAO | Caveolin-1 | CAV1 |
Q03135 |
2 Reference(s) |
| T01QLH | Estrogen receptor | ESR1 |
P03372 |
12 Reference(s) |
| T12PIB | Lysosomal alpha-glucosidase | GAA |
P10253 |
1 Reference(s) |
| T32OC4 | Aldehyde dehydrogenase, mitochondrial | ALDH2 |
P05091 |
1 Reference(s) |
| T54G8J | Protein kinase C delta type | PRKCD |
Q05655 |
3 Reference(s) |
| T22MME | Quinone oxidoreductase | CRYZ |
Q08257 |
1 Reference(s) |
| T02QBS | Cytochrome P450 1A2 | CYP1A2 |
P05177 |
3 Reference(s) |
| T69XVX | Cytochrome P450 1B1 | CYP1B1 |
Q16678 |
3 Reference(s) |
| T80OJF | Interstitial collagenase | MMP1 |
P03956 |
5 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
14 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
17 Reference(s) |
| T84W8G | Aryl hydrocarbon receptor | AHR |
P35869 |
6 Reference(s) |
| T14JSQ | Baculoviral IAP repeat-containing protein 2 | BIRC2 |
Q13490 |
1 Reference(s) |
| T70YKV | Baculoviral IAP repeat-containing protein 3 | BIRC3 |
Q13489 |
1 Reference(s) |
| T79KQO | NF-kappa-B inhibitor alpha | NFKBIA |
P25963 |
3 Reference(s) |
| T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
8 Reference(s) |
| T40B7E | Calcium uniporter protein, mitochondrial | MCU |
Q8NE86 |
1 Reference(s) |
| T05O6O | Estrogen receptor beta | ESR2 |
Q92731 |
10 Reference(s) |
| T22JG3 | Fibroblast growth factor receptor 2 | FGFR2 |
P21802 |
1 Reference(s) |
| T10S5F | Cyclin-dependent kinase 4 | CDK4 |
P11802 |
6 Reference(s) |
| T73LPO | Poly [ADP-ribose] polymerase 1 | PARP1 |
P09874 |
1 Reference(s) |
| T93SFQ | NAD-dependent protein deacetylase sirtuin-1 | SIRT1 |
Q96EB6 |
4 Reference(s) |
| T01E7W | Aurora kinase B | AURKB |
Q96GD4 |
1 Reference(s) |
| T04NYZ | Disintegrin and metalloproteinase domain-containing protein 9 | ADAM9 |
Q13443 |
2 Reference(s) |
| T67JR8 | Heat shock factor protein 1 | HSF1 |
Q00613 |
1 Reference(s) |
| T58XLK | Tyrosine-protein phosphatase non-receptor type 1 | PTPN1 |
P18031 |
2 Reference(s) |
| T69RXK | Cytochrome P450 2C9 | CYP2C9 |
P11712 |
1 Reference(s) |
| T31U13 | Cytochrome P450 2C19 | CYP2C19 |
P33261 |
2 Reference(s) |
| T23P74 | Caspase-9 | CASP9 |
P55211 |
9 Reference(s) |
| T80GUN | 72 kDa type IV collagenase | MMP2 |
P08253 |
4 Reference(s) |
| T04H8Y | Beta-secretase 1 | BACE1 |
P56817 |
2 Reference(s) |
| T06VX0 | MAP/microtubule affinity-regulating kinase 4 | MARK4 |
Q96L34 |
2 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
3 Reference(s) |
| T20IHC | Diacylglycerol O-acyltransferase 1 | DGAT1 |
O75907 |
1 Reference(s) |
| T21DZX | Amine oxidase [flavin-containing] A | MAOA |
P21397 |
1 Reference(s) |
| T76AZQ | Histidine decarboxylase | HDC |
P19113 |
1 Reference(s) |
| T03CZ8 | Catechol O-methyltransferase | COMT |
P21964 |
1 Reference(s) |
| T64UH1 | Nitric oxide synthase, endothelial | NOS3 |
P29474 |
4 Reference(s) |
| T92AMR | Hepatocyte growth factor receptor | MET |
P08581 |
1 Reference(s) |
| T04MBA | Vascular endothelial growth factor receptor 2 | KDR |
P35968 |
2 Reference(s) |
| T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
6 Reference(s) |
| T57L0X | Oxysterols receptor LXR-alpha | NR1H3 |
Q13133 |
1 Reference(s) |
| T82G3R | Integrin beta-3 | ITGB3 |
P05106 |
1 Reference(s) |
| T07TRP | Short transient receptor potential channel 5 | TRPC5 |
Q9UL62 |
2 Reference(s) |
| T02O3F | Endothelial lipase | LIPG |
Q9Y5X9 |
1 Reference(s) |
| T25Y64 | Cholinesterase | BCHE |
P06276 |
2 Reference(s) |
| T64UWL | Taste receptor type 2 member 39 | TAS2R39 |
P59534 |
1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
17 Reference(s) |
| T50SJ8 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | PRKAA2 |
P54646 |
1 Reference(s) |
| T67ZT3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | PTEN |
P60484 |
4 Reference(s) |
| T30VNV | Myeloperoxidase | MPO |
P05164 |
2 Reference(s) |
| T83DDX | Endothelial protein C receptor | PROCR |
Q9UNN8 |
1 Reference(s) |
| T24C0P | Bile acid receptor | NR1H4 |
Q96RI1 |
1 Reference(s) |
| T20RA0 | Adenosine deaminase | ADA |
P00813 |
1 Reference(s) |
| T74QXI | Serine/threonine-protein kinase mTOR | MTOR |
P42345 |
2 Reference(s) |
| T74JJN | Fatty acid synthase | FASN |
P49327 |
2 Reference(s) |
| T53KY7 | Cystic fibrosis transmembrane conductance regulator | CFTR |
P13569 |
3 Reference(s) |
| T69XEM | Tyrosine-protein kinase SYK | SYK |
P43405 |
1 Reference(s) |
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
5 Reference(s) |
| T27LA6 | DNA | DNMT1 |
P26358 |
1 Reference(s) |
| T25UYT | Dual specificity mitogen-activated protein kinase kinase 4 | MAP2K4 |
P45985 |
1 Reference(s) |
| T43N2D | Epidermal growth factor receptor | EGFR |
P00533 |
4 Reference(s) |
| T70NYW | Fibroblast growth factor receptor 4 | FGFR4 |
P22455 |
1 Reference(s) |
| T12BGL | Cytochrome P450 2A6 | CYP2A6 |
P11509 |
2 Reference(s) |
| T24VJT | GDH/6PGL endoplasmic bifunctional protein [Includes: Hexose-6-phosphate dehydrogenase | H6PD |
O95479 |
1 Reference(s) |
| T93YV8 | Tumor necrosis factor receptor superfamily member 11B | TNFRSF11B |
O00300 |
3 Reference(s) |
| T97FEF | Broad substrate specificity ATP-binding cassette transporter ABCG2 | ABCG2 |
Q9UNQ0 |
3 Reference(s) |
| T15RPU | Kinesin-like protein KIF20A | KIF20A |
O95235 |
1 Reference(s) |
| T68DAN | Histone deacetylase 9 | HDAC9 |
Q9UKV0 |
1 Reference(s) |
| T49CBW | Class E basic helix-loop-helix protein 40 | BHLHE40 |
O14503 |
1 Reference(s) |
| T94K7H | Cytochrome P450 7A1 | CYP7A1 |
P22680 |
1 Reference(s) |
| T21EGX | Multidrug resistance-associated protein 1 | ABCC1 |
P33527 |
1 Reference(s) |
| T58FWN | Tyrosine-protein kinase BTK | BTK |
Q06187 |
1 Reference(s) |
| T06Q1R | Amine oxidase [flavin-containing] B | MAOB |
P27338 |
1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
14 Reference(s) |
| T27U96 | Granulocyte-macrophage colony-stimulating factor | CSF2 |
P04141 |
1 Reference(s) |
| T84WE9 | Vascular endothelial growth factor receptor 1 | FLT1 |
P17948 |
1 Reference(s) |
| T29JZ3 | Vascular endothelial growth factor receptor 3 | FLT4 |
P35916 |
1 Reference(s) |
| T64BTV | Interleukin-1 beta | IL1B |
P01584 |
4 Reference(s) |
| T26EZU | Myc proto-oncogene protein | MYC |
P01106 |
2 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
9 Reference(s) |
| T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
2 Reference(s) |
| T24U57 | E-selectin | SELE |
P16581 |
3 Reference(s) |
| T59IKQ | Vascular cell adhesion protein 1 | VCAM1 |
P19320 |
5 Reference(s) |
| T63GUB | Proto-oncogene c-Fos | FOS |
P01100 |
6 Reference(s) |
| T65S3S | Tyrosine-protein kinase JAK2 | JAK2 |
O60674 |
3 Reference(s) |
| T13KGH | Tyrosinase | TYR |
P14679 |
2 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
13 Reference(s) |
| T81I4T | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | PRKAA1 |
Q13131 |
3 Reference(s) |
| T09GFP | Maltase-glucoamylase, intestinal [Includes: Maltase | MGAM |
O43451 |
1 Reference(s) |
| T74D4Y | CASP8 and FADD-like apoptosis regulator | CFLAR |
O15519 |
1 Reference(s) |
| T95K8Q | Intestinal-type alkaline phosphatase | ALPI |
P09923 |
1 Reference(s) |
| T98FWP | NF-kappa-B essential modulator | IKBKG |
Q9Y6K9 |
1 Reference(s) |
| T94VM4 | 17-beta-hydroxysteroid dehydrogenase type 2 (17-beta-HSD 2) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Estradiol 17-beta-dehydrogenase 2) (EC 1.1.1.62) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 9C member 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239) | HSD17B2 |
P37059 |
1 Reference(s) |
| T44LWL | Transcription factor p65 | RELA |
Q04206 |
11 Reference(s) |
| T74I49 | Bcl-2-like protein 1 | BCL2L1 |
Q07817 |
2 Reference(s) |
| T75HMM | Induced myeloid leukemia cell differentiation protein Mcl-1 | MCL1 |
Q07820 |
1 Reference(s) |
| T14LSK | E3 ubiquitin-protein ligase XIAP | XIAP |
P98170 |
1 Reference(s) |
| T42XY2 | Insulin-like growth factor 1 receptor | IGF1R |
P08069 |
4 Reference(s) |
| T93WZG | G1/S-specific cyclin-D1 | CCND1 |
P24385 |
8 Reference(s) |
| T54VQA | Cyclin-dependent kinase inhibitor 2A | CDKN2A |
P42771 |
3 Reference(s) |
| T07TMB | Cyclin-dependent kinase 1 | CDK1 |
P06493 |
7 Reference(s) |
| T86UXL | Cyclin-A2 | CCNA2 |
P20248 |
2 Reference(s) |
| T24LXT | G2/mitotic-specific cyclin-B1 | CCNB1 |
P14635 |
8 Reference(s) |
| T64W2K | Cyclin-dependent kinase inhibitor 1 | CDKN1A |
P38936 |
16 Reference(s) |
| T35QZO | Cytochrome c | CYCS |
P99999 |
3 Reference(s) |
| T06PVX | E3 ubiquitin-protein ligase Mdm2 | MDM2 |
Q00987 |
2 Reference(s) |
| T91T8I | Glucose-6-phosphatase catalytic subunit 1 | G6PC1 |
P35575 |
1 Reference(s) |
| T06IYF | Adenomatous polyposis coli protein | APC |
P25054 |
1 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
5 Reference(s) |
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
7 Reference(s) |
| T50GQE | Interleukin-13 | IL13 |
P35225 |
1 Reference(s) |
| T22IMH | Cyclin-dependent kinase 6 | CDK6 |
Q00534 |
1 Reference(s) |
| T02WMA | Ornithine decarboxylase | ODC1 |
P11926 |
1 Reference(s) |
| T84P70 | Urokinase-type plasminogen activator | PLAU |
P00749 |
2 Reference(s) |
| T36SOV | Plasminogen activator inhibitor 1 | SERPINE1 |
P05121 |
1 Reference(s) |
| T62QDU | Alpha- and gamma-adaptin-binding protein p34 | AAGAB |
Q6PD74 |
1 Reference(s) |
| T26KIE | Transcription factor AP-1 | JUN |
P05412 |
14 Reference(s) |
| T37VLU | Interferon gamma | IFNG |
P01579 |
1 Reference(s) |
| T88B8X | Insulin receptor | INSR |
P06213 |
2 Reference(s) |
| T68SE0 | Solute carrier family 2, facilitated glucose transporter member 4 | SLC2A4 |
P14672 |
4 Reference(s) |
| T91OUC | Mucin-5AC | MUC5AC |
P98088 |
2 Reference(s) |
| T45G32 | Proto-oncogene tyrosine-protein kinase Src | SRC |
P12931 |
2 Reference(s) |
| T21S10 | Heterogeneous nuclear ribonucleoproteins A2/B1 | HNRNPA2B1 |
P22626 |
1 Reference(s) |
| T46K2X | Heat shock 70 kDa protein 4 | HSPA4 |
P34932 |
1 Reference(s) |
| T37BP1 | Serine/threonine-protein kinase pim-1 | PIM1 |
P11309 |
1 Reference(s) |
| T71DUF | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | PPP3CA |
Q08209 |
1 Reference(s) |
| T04AHN | 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 | HSD3B2 |
P26439 |
1 Reference(s) |
| T23K1O | Calmodulin | CALM3;CALML2;CAM3;CAMC;CAMIII |
P62158 |
1 Reference(s) |
| T09TS5 | Gamma-aminobutyric acid type B receptor subunit 1 | GABBR1 |
Q9UBS5 |
1 Reference(s) |
| T74ETU | Steroid 21-hydroxylase | CYP21A2 |
P08686 |
2 Reference(s) |
| T50WUM | Leucine--tRNA ligase, cytoplasmic | LARS1 |
Q9P2J5 |
1 Reference(s) |
| T30V3R | 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 | HSD3B1 |
P14060 |
2 Reference(s) |
| T67HAF | Signal transducer and activator of transcription 1-alpha/beta | STAT1 |
P42224 |
3 Reference(s) |
| T29GH0 | Trefoil factor 1 | TFF1 |
P04155 |
2 Reference(s) |
| T98JPP | Carnitine O-palmitoyltransferase 1, liver isoform | CPT1A |
P50416 |
1 Reference(s) |
| T73S71 | Apolipoprotein B-100 | APOB |
P04114 |
2 Reference(s) |
| T49PL1 | Low-density lipoprotein receptor | LDLR |
P01130 |
5 Reference(s) |
| T92Q77 | Type I iodothyronine deiodinase | DIO1 |
P49895 |
1 Reference(s) |
| T48XM4 | Glutathione S-transferase Mu 2 | GSTM2 |
P28161 |
1 Reference(s) |
| T87WYU | Glutathione S-transferase Mu 1 | GSTM1 |
P09488 |
1 Reference(s) |
| T41INV | Nuclear receptor subfamily 1 group I member 3 | NR1I3 |
Q14994 |
1 Reference(s) |
| T87DEX | Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase | XDH |
P47989 |
2 Reference(s) |
| T54OSZ | Pleckstrin | PLEK |
P08567 |
2 Reference(s) |
| T63FNY | NSFL1 cofactor p47 | NSFL1C |
Q9UNZ2 |
2 Reference(s) |
| T99XQ3 | DNA topoisomerase 1 | TOP1 |
P11387 |
1 Reference(s) |
| T38BR0 | G1/S-specific cyclin-D2 | CCND2 |
P30279 |
3 Reference(s) |
| T38T1U | Caspase-8 | CASP8 |
Q14790 |
2 Reference(s) |
| T75B9S | Cyclic AMP-responsive element-binding protein 1 | CREB1 |
P16220 |
1 Reference(s) |
| T32UNL | Lens fiber major intrinsic protein | MIP |
P30301 |
1 Reference(s) |
| T02GD4 | Tumor necrosis factor ligand superfamily member 6 | FASLG |
P48023 |
3 Reference(s) |
| T97KL5 | Microsomal glutathione S-transferase 1 | MGST1 |
P10620 |
2 Reference(s) |
| T81BH5 | Sulfotransferase 1A1 | SULT1A1 |
P50225 |
2 Reference(s) |
| T32SPJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | PIK3CG |
P48736 |
1 Reference(s) |
| T43R3A | TIR domain-containing adapter molecule 2 | TICAM2 |
Q86XR7 |
1 Reference(s) |
| T28PHS | Angiotensin-converting enzyme | ACE |
P12821 |
1 Reference(s) |
| T18LPB | Cytochrome P450 11B2, mitochondrial | CYP11B2 |
P19099 |
1 Reference(s) |
| T70EJM | Eotaxin | CCL11 |
P51671 |
1 Reference(s) |
| T54SZZ | Endoplasmic reticulum chaperone BiP | HSPA5 |
P11021 |
3 Reference(s) |
| T20MBF | Serotransferrin | TF |
P02787 |
1 Reference(s) |
| T46AQJ | Glutathione S-transferase P | GSTP1 |
P09211 |
4 Reference(s) |
| T95QJ9 | G1/S-specific cyclin-D3 | CCND3 |
P30281 |
1 Reference(s) |
| T98RXH | Focal adhesion kinase 1 | PTK2 |
Q05397 |
1 Reference(s) |
| T91D6X | Protein Wnt-3a | WNT3A |
P56704 |
1 Reference(s) |
| T61SU2 | Coxsackievirus and adenovirus receptor | CXADR |
P78310 |
1 Reference(s) |
| T36YWU | Kelch-like ECH-associated protein 1 | KEAP1 |
Q14145 |
2 Reference(s) |
| T17CZC | Tissue factor | F3 |
P13726 |
1 Reference(s) |
| T56MD7 | Glutathione hydrolase 5 proenzyme | GGT5 |
P36269 |
1 Reference(s) |
| T53QS9 | Glutamate--cysteine ligase catalytic subunit | GCLC |
P48506 |
1 Reference(s) |
| T85AXP | Cytochrome P450 3A4 | CYP3A4 |
P08684 |
2 Reference(s) |
| T53AOE | Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide | TGFB1 |
P01137 |
7 Reference(s) |
| T34DZ7 | Interleukin-2 | IL2 |
P60568 |
2 Reference(s) |
| T89L4V | Insulin | INS |
P01308 |
2 Reference(s) |
| T21Q0D | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR |
P04035 |
4 Reference(s) |
| T16A2X | Catalase | CAT |
P04040 |
4 Reference(s) |
| T61OY3 | UDP-glucuronosyltransferase 1A1 | UGT1A1 |
P22309 |
1 Reference(s) |
| T19JEU | Beta-galactosidase | GLB1 |
P16278 |
1 Reference(s) |
| T78VUO | RAF proto-oncogene serine/threonine-protein kinase | RAF1 |
P04049 |
2 Reference(s) |
| T20NCI | Serine-protein kinase ATM | ATM |
Q13315 |
1 Reference(s) |
| T28EY5 | Serine/threonine-protein kinase Chk2 | CHEK2 |
O96017 |
2 Reference(s) |
| T17UP9 | C-C motif chemokine 2 | CCL2 |
P13500 |
1 Reference(s) |
| T54CIF | Interleukin-8 | CXCL8 |
P10145 |
3 Reference(s) |
| T68NCI | Aldo-keto reductase family 1 member B1 | AKR1B1 |
P15121 |
1 Reference(s) |
| T77PFO | Histone deacetylase 6 | HDAC6 |
Q9UBN7 |
1 Reference(s) |
| T26UZV | Dual specificity mitogen-activated protein kinase kinase 5 | MAP2K5 |
Q13163 |
1 Reference(s) |
| T44S1A | Apolipoprotein A-I | APOA1 |
P02647 |
1 Reference(s) |
| T38K2W | Receptor tyrosine-protein kinase erbB-2 | ERBB2 |
P04626 |
2 Reference(s) |
| T79A7K | Protein PML | PML |
P29590 |
1 Reference(s) |
| T19Z2N | Nuclear receptor corepressor 1 | NCOR1 |
O75376 |
1 Reference(s) |
| T68BGR | Glial fibrillary acidic protein | GFAP |
P14136 |
1 Reference(s) |
| T25NSJ | Mitogen-activated protein kinase 3 | MAPK3 |
P27361 |
4 Reference(s) |
| T31P1D | Metalloproteinase inhibitor 1 | TIMP1 |
P01033 |
2 Reference(s) |
| T39M81 | DNA-(apurinic or apyrimidinic site) endonuclease | APEX1 |
P27695 |
1 Reference(s) |
| T05WU9 | Serine/threonine-protein phosphatase 2A activator | PTPA |
Q15257 |
1 Reference(s) |
| T98QOA | DNA-dependent protein kinase catalytic subunit | PRKDC |
P78527 |
1 Reference(s) |
| T30D9G | Superoxide dismutase [Cu-Zn] | SOD1 |
P00441 |
1 Reference(s) |
| T23RXU | Glutathione reductase, mitochondrial | GSR |
P00390 |
1 Reference(s) |
| T59DDI | Liver carboxylesterase 1 | CES1 |
P23141 |
1 Reference(s) |
| T03NWF | Sterol O-acyltransferase 1 | SOAT1 |
P35610 |
1 Reference(s) |
| T95RKQ | Sterol O-acyltransferase 2 | SOAT2 |
O75908 |
1 Reference(s) |
| T35FQV | Microsomal triglyceride transfer protein large subunit | MTTP |
P55157 |
2 Reference(s) |
| T30TYH | Phospholipase A2 | PLA2G1B |
P04054 |
1 Reference(s) |
| T87WH7 | Fos-related antigen 2 | FOSL2 |
P15408 |
1 Reference(s) |
| T52CKD | Pro-epidermal growth factor | EGF |
P01133 |
1 Reference(s) |
| T95K0K | Interferon alpha-1/13 | IFNA1; IFNA13 |
P01562 |
1 Reference(s) |
| T64LKA | Bile salt export pump | ABCB11 |
O95342 |
2 Reference(s) |
| T84CEG | Claudin-5 | CLDN5 |
O00501 |
1 Reference(s) |
| T30AEN | Aquaporin-5 | AQP5 |
P55064 |
1 Reference(s) |
| T47RAK | NA | MIR145 |
NA |
1 Reference(s) |
| T75NEV | Aquaporin-1 | AQP1 |
P29972 |
1 Reference(s) |
| T37SV3 | Occludin | OCLN |
Q16625 |
1 Reference(s) |
| T69F5W | Forkhead box protein D3 | FOXD3 |
Q9UJU5 |
1 Reference(s) |
| T13I7C | Transforming growth factor beta-2 proprotein | TGFB2 |
P61812 |
2 Reference(s) |
| T44EUX | Fragile X mental retardation syndrome-related protein 1 | FXR1 |
P51114 |
1 Reference(s) |
| T92LK2 | Tumor necrosis factor ligand superfamily member 10 | TNFSF10 |
P50591 |
1 Reference(s) |
| T26CFB | DNA damage-inducible transcript 3 protein | DDIT3 |
P35638;P0DPQ6 |
2 Reference(s) |
| T55IIP | CDGSH iron-sulfur domain-containing protein 1 | CISD1 |
Q9NZ45 |
1 Reference(s) |
| T97XMW | NA | MIR374A |
NA |
1 Reference(s) |
| T40G6B | Prostaglandin reductase 1 | PTGR1 |
Q14914 |
3 Reference(s) |
| T04TWI | CD40 ligand | CD40LG |
P29965 |
1 Reference(s) |
| T41TXS | Retinoblastoma-associated protein | RB1 |
P06400 |
2 Reference(s) |
| T92UBJ | Acetyl-CoA carboxylase 1 | ACACA |
Q13085 |
1 Reference(s) |
| T87WMV | Sodium/potassium-transporting ATPase subunit gamma | FXYD2 |
P54710 |
1 Reference(s) |
| T00KKS | Sodium/iodide cotransporter | SLC5A5 |
Q92911 |
1 Reference(s) |
| T78ILO | Stearoyl-CoA desaturase | SCD |
O00767 |
1 Reference(s) |
| T96G89 | Fatty acid-binding protein, adipocyte | FABP4 |
P15090 |
1 Reference(s) |
| T90ORW | Bcl2-associated agonist of cell death | BAD |
Q92934 |
2 Reference(s) |
| T04UTZ | G1/S-specific cyclin-E1 | CCNE1 |
P24864 |
1 Reference(s) |
| T22I6G | Cyclin-dependent kinase 4 inhibitor C (Cyclin-dependent kinase 6 inhibitor) (p18-INK4c) (p18-INK6) | CDKN2C |
P42773 |
1 Reference(s) |
| T25S1M | Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1) (Fragment) | p27 kip1 |
O43806 |
1 Reference(s) |
| T05PKX | Steroid 17-alpha-hydroxylase/17,20 lyase | CYP17A1 |
P05093 |
1 Reference(s) |
| T69NG6 | Interleukin-10 | IL10 |
P22301 |
2 Reference(s) |
| T27LTU | C5a anaphylatoxin chemotactic receptor 1 | C5AR1 |
P21730 |
1 Reference(s) |
| T00QMT | NA | MIR15B |
NA |
1 Reference(s) |
| T06ADX | Tyrosine-protein kinase receptor UFO | AXL |
P30530 |
1 Reference(s) |
| T30L86 | Tumor necrosis factor receptor superfamily member 10B | TNFRSF10B |
O14763 |
1 Reference(s) |
| T52RGZ | Growth/differentiation factor 15 | GDF15 |
Q99988 |
1 Reference(s) |
| T40JZG | GPI-anchor transamidase | PIGK |
Q92643 |
1 Reference(s) |
| T20TPU | Histone acetyltransferase KAT2B | KAT2B |
Q92831 |
1 Reference(s) |
| T57HGP | Tumor necrosis factor receptor superfamily member 6 | FAS |
P25445 |
2 Reference(s) |
| T07NZK | Low affinity immunoglobulin epsilon Fc receptor | FCER2 |
P06734 |
1 Reference(s) |
| T11GHO | Transforming protein RhoA | RHOA |
P61586 |
1 Reference(s) |
| T34AYH | Solute carrier family 52, riboflavin transporter, member 1 | SLC52A1 |
Q9NWF4 |
1 Reference(s) |
| T36I66 | Metallothionein-2 | MT2A |
P02795 |
1 Reference(s) |
| T90ZS8 | Endothelin-converting enzyme 1 | ECE1 |
P42892 |
1 Reference(s) |
| T16IWB | Growth arrest and DNA damage-inducible protein GADD45 alpha | GADD45A |
P24522 |
1 Reference(s) |
| T29CYD | BRCA1-associated RING domain protein 1 | BARD1 |
Q99728 |
1 Reference(s) |
| T41SFE | Histone acetyltransferase p300 | EP300 |
Q09472 |
1 Reference(s) |
| T57R3V | Proliferation marker protein Ki-67 | MKI67 |
P46013 |
1 Reference(s) |
| T82I76 | Ubiquitin carboxyl-terminal hydrolase BAP1 | BAP1 |
Q92560 |
1 Reference(s) |
| T82S9G | DNA repair protein RAD51 homolog 1 | RAD51 |
Q06609 |
1 Reference(s) |
| T53QOD | ATP synthase subunit beta, mitochondrial | ATP5F1B |
P06576 |
1 Reference(s) |
| T63SUZ | NADH-ubiquinone oxidoreductase chain 6 | MT-ND6 |
P03923 |
1 Reference(s) |
| T46HRF | Growth hormone receptor | GHR |
P10912 |
1 Reference(s) |
| T70SFS | Superoxide dismutase [Mn], mitochondrial | SOD2 |
P04179 |
1 Reference(s) |
| T28B0B | Monocarboxylate transporter 8 | SLC16A2 |
P36021 |
1 Reference(s) |
| T53GFX | Arginase-1 | ARG1 |
P05089 |
1 Reference(s) |
| T07VO1 | Steroid hormone receptor ERR1 | ESRRA |
P11474 |
2 Reference(s) |
| T99ARN | Forkhead box protein P3 | FOXP3 |
Q9BZS1 |
1 Reference(s) |
| T18DUA | Tight junction protein ZO-1 | TJP1 |
Q07157 |
1 Reference(s) |
| T09BRP | NA | PKB_RS07820 |
NA |
1 Reference(s) |
| T10IWJ | Bone morphogenetic protein receptor type-2 | BMPR2 |
Q13873 |
1 Reference(s) |
| T75PC7 | NA | MIR21 |
NA |
1 Reference(s) |
| T14DX3 | Ribosomal protein S6 kinase alpha-3 | RPS6KA3 |
P51812 |
1 Reference(s) |
| T66WWM | Claudin-2 | CLDN2 |
P57739 |
1 Reference(s) |
| T90XMB | Ubiquitin carboxyl-terminal hydrolase 5 | USP5 |
P45974 |
1 Reference(s) |
| T42K6K | M-phase inducer phosphatase 3 | CDC25C |
P30307 |
2 Reference(s) |
| T33KFW | Matrilysin | MMP7 |
P09237 |
1 Reference(s) |
| T39RV3 | Dual specificity mitogen-activated protein kinase kinase 1 | MAP2K1 |
Q02750 |
1 Reference(s) |
| T66S13 | Dual specificity mitogen-activated protein kinase kinase 2 | MAP2K2 |
P36507 |
1 Reference(s) |
| T85BSD | Mitogen-activated protein kinase kinase kinase 20 | MAP3K20 |
Q9NYL2 |
1 Reference(s) |
| T72TF8 | Methylcytosine dioxygenase TET1 | TET1 |
Q8NFU7 |
1 Reference(s) |
| T39WPZ | Mitogen-activated protein kinase 9 | MAPK9 |
P45984 |
2 Reference(s) |
| T07S0E | BDNF/NT-3 growth factors receptor | NTRK2 |
Q16620 |
1 Reference(s) |
| T08B2M | M-phase inducer phosphatase 1 | CDC25A |
P30304 |
1 Reference(s) |
| T33UEM | Lactoperoxidase | LPO |
P22079 |
1 Reference(s) |
| T03TJ0 | Interleukin-33 | IL33 |
O95760 |
1 Reference(s) |
| T31VDH | Myeloid differentiation primary response protein MyD88 | MYD88 |
Q99836 |
1 Reference(s) |
| T80U0C | Glutathione synthetase | GSS |
P48637 |
1 Reference(s) |
| T34HYH | Interleukin-1 alpha | IL1A |
P01583 |
1 Reference(s) |
| T84VZG | Ryanodine receptor 1 | RYR1 |
P21817 |
1 Reference(s) |
| T04HTN | Cyclic AMP-dependent transcription factor ATF-3 | ATF3 |
P18847 |
1 Reference(s) |
| T05XOE | Macrophage mannose receptor 1 | MRC1 |
P22897 |
1 Reference(s) |
| T94H37 | Cadherin-1 | CDH1 |
P12830 |
1 Reference(s) |
| T09KPZ | Vimentin | VIM |
P08670 |
1 Reference(s) |
| T28K6X | Insulin receptor substrate 1 | IRS1 |
P35568 |
1 Reference(s) |
| T02HSM | Neuroglobin | NGB |
Q9NPG2 |
1 Reference(s) |
| T62F1Y | Glutathione S-transferase A2 | GSTA2 |
P09210 |
1 Reference(s) |
| T20E5P | Cytochrome b-245 heavy chain | CYBB |
P04839 |
1 Reference(s) |
| T80OPZ | NADPH oxidase 4 | NOX4 |
Q9NPH5 |
1 Reference(s) |
| T14ENF | Microtubule-associated protein 2 | MAP2 |
P11137 |
1 Reference(s) |
| T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
1 Reference(s) |
| T93VFT | Endothelin-1 | EDN1 |
P05305 |
1 Reference(s) |
| T87QUW | Actin, aortic smooth muscle | ACTA2 |
P62736 |
1 Reference(s) |
| T04WT7 | Fibronectin | FN1 |
P02751 |
2 Reference(s) |
| T38N69 | Lymphokine-activated killer T-cell-originated protein kinase | PBK |
Q96KB5 |
1 Reference(s) |
| T89VFL | Alpha-crystallin B chain | CRYAB |
P02511 |
1 Reference(s) |
| T04A2Q | Serine/threonine-protein kinase PLK1 | PLK1 |
P53350 |
1 Reference(s) |
| T82S6C | Hexokinase-4 | GCK |
P35557 |
1 Reference(s) |
| T00F43 | Mediator of DNA damage checkpoint protein 1 | MDC1 |
Q14676 |
1 Reference(s) |
| T21YK3 | Cell division cycle protein 20 homolog | CDC20 |
Q12834 |
1 Reference(s) |
| T75I26 | Mitotic checkpoint serine/threonine-protein kinase BUB1 | BUB1 |
O43683 |
1 Reference(s) |
| T03G09 | Tumor necrosis factor ligand superfamily member 11 | TNFSF11 |
O14788 |
2 Reference(s) |
| T34N64 | NA | MIR29B1 |
NA |
1 Reference(s) |
| T30NJL | Electrogenic sodium bicarbonate cotransporter 1 | SLC4A4 |
Q9Y6R1 |
1 Reference(s) |
| T33JS5 | CCN family member 2 | CCN2 |
P29279 |
2 Reference(s) |
| T88MR0 | Solute carrier family 26 member 6 | SLC26A6 |
Q9BXS9 |
1 Reference(s) |
| T91MKC | Runt-related transcription factor 2 | RUNX2 |
Q13950 |
1 Reference(s) |
| T31SX8 | Bone morphogenetic protein 2 | BMP2 |
P12643 |
1 Reference(s) |
| T17X6I | DNA fragmentation factor subunit alpha | DFFA |
O00273 |
1 Reference(s) |
| T16S8T | Baculoviral IAP repeat-containing protein 7 | BIRC7 |
Q96CA5 |
1 Reference(s) |
| T49A2A | Sodium/hydrogen exchanger 1 | SLC9A1 |
P19634 |
1 Reference(s) |
| T25SPW | Sodium/hydrogen exchanger 2 | SLC9A2 |
Q9UBY0 |
1 Reference(s) |
| T09HVO | Sodium/hydrogen exchanger 3 | SLC9A3 |
P48764 |
1 Reference(s) |
| T33BF9 | DNA | DNMT3B |
Q9UBC3 |
1 Reference(s) |
| T76B0A | Gap junction alpha-1 protein | GJA1 |
P17302 |
1 Reference(s) |
| T74V1Z | Dual specificity mitogen-activated protein kinase kinase 7 | MAP2K7 |
O14733 |
1 Reference(s) |
| T72BXP | Platelet endothelial cell adhesion molecule | PECAM1 |
P16284 |
1 Reference(s) |
| T24LWC | Sodium-dependent dopamine transporter | SLC6A3 |
Q01959 |
1 Reference(s) |
| T89SY7 | Zinc finger and BTB domain-containing protein 16 | ZBTB16 |
Q05516 |
1 Reference(s) |
| T20H9F | Stromelysin-1 | MMP3 |
P08254 |
1 Reference(s) |
| T70B7U | Angiotensin-converting enzyme 2 | ACE2 |
Q9BYF1 |
1 Reference(s) |
| T27BN7 | Protachykinin-1 | TAC1 |
P20366 |
1 Reference(s) |
| T33OSQ | Sterol regulatory element-binding protein 1 | SREBF1 |
P36956 |
1 Reference(s) |
| T95IYZ | Adiponectin | ADIPOQ |
Q15848 |
1 Reference(s) |
| T84XYQ | Polycystin-2 | PKD2 |
Q13563 |
1 Reference(s) |
| T38EQ6 | NAD(P)H dehydrogenase [quinone] 1 | NQO1 |
P15559 |
1 Reference(s) |
Related Compounds (Total: 44)
C0193
Name: Liquiritin
C0041
Name: Emodin
C0152
Name: Isoliquiritigenin
C0156
Name: Isoquercetin
C1208
Name: Calycosin
key description of the interaction between compound and target