Type | Detail |
---|---|
Target ID | T92Q77 |
Protein Name | Type I iodothyronine deiodinase |
Uniprot ID |
P49895 |
Protein Name Alias | EC 1.21.99.4; 5DI; DIOI; Type 1 DI; Type-I 5'-deiodinase |
Gene ID |
1733 |
Gene Symbol | DIO1 |
Gene Alias | ITDI1; TXDI1 |
TTD | T16792: Successful target |
Pfam | PF00837 |
GO |
0005789:endoplasmic reticulum membrane
0042446:hormone biosynthetic process 0016021:integral component of membrane 0042403:thyroid hormone metabolic process 0008430:selenium binding 0006590:thyroid hormone generation 0004800:thyroxine 5'-deiodinase activity 0006520:cellular amino acid metabolic process 0005886:plasma membrane |
PDB | NA |
Drugbank | DB09100 |
KEGG | hsa:1733 |
Herb id | Chinese Pin Yin | Chinese Character | English Name | Latin Name |
---|---|---|---|---|
H0064 | Jin Yin Hua | 金银花 | Japanese honeysuckle | Lonicera japonica |
H0004 | Huo Xiang | 藿香 | Patchouli | Pogostemon cablin |
H1127 | Guang Shan Zha | 广山楂 | Chinese hawthorn | Crataegus pinnatifida |
H0698 | Ya Zao | 牙皂 | Chinese honeylocust abnormal fruit | Gleditsia sinensis |
H0246 | Mi Ma Huang | 蜜麻黄 | Ephedra equisetin | Ephedra sinica |
H1026 | Fan Hun Cao | 返魂草 | Tatarian aster | Aster tataricus |
H0071 | Bai Ye | 柏叶 | Chinese arborvitae twig | Platycladus orientalis |
H0802 | Zhi Geng | 枳梗 | NA | Citrus aurantium |
H0779 | Zao Jiao Zhen | 皂角针 | Chinese honeylocust spine | Gleditsia sinensis |
H0853 | Zi Wan | 紫菀 | Tatarion aster | Aster tataricus |
H0446 | Sheng Jiang | 生姜 | Fresh common ginger | Zingiber officinale |
H0043 | Jie Zi | 芥子 | India mustard seed | Brassica juncea |
H0658 | Xiao Fan Tian Hua | 肖梵天花 | Caesarweed | Urena lobata |
H1021 | E Da Xia | 莪大夏 | NA | Oxytropis falcata |
H1061 | Bai He | 百合 | Lily | Lilium brownii |
H0002 | Hui Xiang | 茴香 | Fennel fruit | Foeniculum vulgare |
H0198 | Ma Huang Gao | 麻黄膏 | Chinese ephedra | Ephedra sinica |
H0357 | Ren Shen | 人参 | Ginseng | Panax ginseng |
H0818 | Zhi Zi | 栀子 | Cape jasmine fruit | Gardenia jasminoides |
H1223 | Huai Hun Cao | 还魂草 | NA | Aster tataricus |
H0804 | Zhi Ke | 枳壳 | Seville ora nge unripe fruit | Citrus aurantium |
H0344 | Qing Guo | 青果 | Olive | Canarium album |
H1102 | Gu Sui Bu | 骨碎补 | Fortune’s drynaria rhizome | Drynaria fortunei |
H0419 | Shan Zha | 山楂 | Chinese hawthorn | Crataegus pinnatifida |
H0190 | Lv Dou | 绿豆 | Common sainfoin | Onobrychis viciifolia |
H0424 | Shan Zhi | 山栀 | Cape jasmine | Gardenia jasminoides |
H0270 | Mu Hu Die | 木蝴蝶 | Indian trumpetflower | Oroxylum indicum |
H1072 | Gan Cao Gao | 甘草膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
H0813 | Zhi Shi | 枳实 | Seville orange young fruit | Citrus aurantium |
H0860 | Zong Lv Zi | 棕榈子 | NA | Trachycarpus fortunei |
H0302 | Ou Fen | 藕粉 | Hindu lotus large rhizome | Nelumbo nucifera |
H0142 | Liang Jiang | 良姜 | NA | Alpinia officinarum |
H1010 | Du Huo Xiang | 杜藿香 | Patchouli | Pogostemon cablin |
H0793 | Zhao Shan Bai | 照山白 | Manchurian rhododendron | Rhododendron micranthum |
H0200 | Ma Huang Gen | 麻黄根 | Chinese ephedra root | Ephedra sinica |
H0115 | Kuan Dong Hua | 款冬花 | Common coltsfoot | Tussilago farfara |
H0345 | Qing Guo Tan | 青果炭 | white olive | Canarium album |
H1075 | Gan Cao Liu Jin Gao | 甘草流浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
H0708 | Yuan Hua Gen | 芫花根 | Lilac daphne root | Daphne genkwa |
H0016 | Ji Xue Cao | 积雪草 | Asiatic pennywort | Centella asiatica |
H0288 | Niu Bang Cao | 牛蒡草 | greater burdock | Arctium lappa |
H0897 | Chuan Lian | 川楝 | Chinaberry | Melia azedarach |
H0227 | Mang Guo Ye | 芒果叶 | Mango leaf | Mangifera indica |
H1073 | Gan Cao Jie | 甘草节 | Glycyrrhiza uralensis fisch | Glycyrrhiza uralensis |
H0250 | Mi Zi Wan | 蜜紫菀 | Tatarian aster | Aster tataricus |
H0065 | Jin Yin Hua Ti Qu Ye | 金银花提取液 | Japanese honeysuckle | Lonicera japonica |
H0083 | Jiu Jie Cha | 九节茶 | Glabrous sarcandra | Sarcandra glabra |
H0570 | Tu Fu Ling | 土茯苓 | Glabrous greenbrier | Smilax glabra |
H0857 | Zong Ban Tan | 棕板炭 | NA | Trachycarpus fortunei |
H1068 | Bai He Liu Jin Gao | 百合流浸膏 | Lily | Lilium brownii |
H1138 | Bai Jiang Cao | 败酱草 | All - grass of dahurian patrinia | Thlaspi arvense |
H0958 | Dang Shen | 党参 | Pilose asiabell | Codonopsis pilosula |
H1055 | Bai Guo Ren | 白果仁 | ginkgo | Ginkgo biloba |
H0902 | Chun Pi | 椿皮 | Ailanthus bark, tree of heaven bark | Ailanthi cortex |
H0275 | Mu Zei | 木贼 | Common scouring rush | Equisetum hiemale |
H0462 | Shi Liu | 石榴 | Pomegranate fruit | Punica granatum |
H0541 | Cang Qie Gen | 藏茄根 | Tibetan eggplant root | Anisodus tanguticus |
H1053 | Fu Ling | 茯苓 | Indian bread | Wolfiporia cocos |
H1124 | Guang Jin Qian Cao | 广金钱草 | Snowbellleaf tickclover | Desmodium styracifolium |
H1225 | Huai Mi | 槐米 | NA | Sophora japonica |
H1036 | Fen Dan Pi | 粉丹皮 | Tree peony bark | Paeonia suffruticosa |
H1034 | Fei Yang Cao | 飞杨草 | NA | Euphorbia hirta |
H1029 | Fang Er Cha | 方儿茶 | khair in hindi | Senegalia catechu |
H0391 | Sang Pi | 桑皮 | Prepared root-bark white mulberry | Morus alba |
H0925 | Da Fu Zi | 大腹子 | Areca palm | Areca catechu |
H0591 | Wei Ling Cai | 委陵菜 | Chinese cinquefoil | Potentilla chinensis |
H0219 | Man Shan Hong | 满山红 | Dahurian rhododendron | Rhododendron dauricum |
H1133 | Gui Jian Yu | 鬼箭羽 | Winged euonymus | Euonymus alatus |
H0269 | Mu Gua | 木瓜 | Chinese floweringquince | Chaenomeles sinensis |
H0470 | Shi Ye | 柿叶 | Persimmon leaf | Diospyros kaki |
H0396 | Sang Ye | 桑叶 | White mulberry leaf | Morus alba |
H1222 | Huai Hua | 槐花 | flower bud of japanese pagodatree | Sophora japonica |
H0901 | Chun Gen Teng | 春根藤 | Twig and leaf of creeping psychotria | Psychotria serpens |
H0423 | Shan Zha Ye | 山楂叶 | NA | Crataegi folium |
H0425 | Shan Zhi Ma | 山芝麻 | Narrowleaf screwtree | Helicteres angustifolia |
H0045 | Jin Fei Cao | 金沸草 | Japanese inula | Inula japonica |
H1227 | Huai Zhi | 槐枝 | NA | Sophora japonica |
H1070 | Gan Cao Gan Gao Fen | 甘草干膏粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
H0120 | Ban Bian Qi | 半边旗 | pinnated brake herb | Pteris semipinnata |
H1246 | Huang Pi Ye | 黄皮叶 | Chinese wampee leaf | Clausena lansium |
H1187 | Hong Guan Yao | 红管药 | NA | Aster ageratoides |
H0856 | Zong Ban | 棕板 | NA | Trachycarpus fortunei |
H0696 | Ya Jiao Ai | 鸭脚艾 | Ghostplant wormwood | Artemisia lactiflora |
H0109 | Ku Lian Zi | 苦楝子 | NA | Melia azedarach |
H0572 | Tu Huo Xiang | 土藿香 | Patchouli | Pogostemon cablin |
H0974 | Di Jin Cao | 地锦草 | Humifuse euphorbia | Euphorbia humifusa |
H0420 | Shan Zha Chou Gao | 山楂稠膏 | Chinese hawthorn | Crataegus pinnatifida |
H0717 | Yang Cong Tou | 洋葱头 | Common onion | Allium cepa |
H0181 | Luo Bu Ma | 罗布麻 | Dogbane | Apocynum venetum |
H0069 | Jin Ying Zi Ti Qu Ye | 金樱子提取液 | Cherokee rose seed | Rosa laevigata |
H0426 | Shan Zhi Ma Gan Jin Gao | 山芝麻干浸膏 | Narrowleaf screwtree | Helicteres angustifolia |
H0951 | Dan Shen Jin Gao | 丹参浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
H0472 | Shu Da Huang | 熟大黄 | NA | Rheum palmatum |
H0413 | Shan Lang Dang | 山莨菪 | NA | Anisodus tanguticus |
H1188 | Hong Hua | 红花 | Safflower | Carthamus tinctorius |
H1097 | Gong Ding Xiang | 公丁香 | NA | Syzygium aromaticum |
H1202 | Hu Huang Lian | 胡黄连 | Picrorhiza | Picrorhiza kurrooa |
H0201 | Ma Huang Jin Gao | 麻黄浸膏 | Chinese ephedra | Ephedra sinica |
H0574 | Cao Dou Kou | 草豆蔻 | Katsumada galangal | Alpinia katsumadai |
H1046 | Feng Xian Tou Gu Cao | 凤仙透骨草 | Spotted snapweed | Impatiens balsamina |
H0711 | Yuan Hua Zhi Tiao | 芫花枝条 | stem of lilac daphne | Daphne genkwa |
H0716 | Yang Cong | 洋葱 | Common onion | Allium cepa |
H0979 | Di Yu | 地榆 | Garden burnet | Sanguisorba officinalis |
H0243 | Mi Kuan Dong Hua | 蜜款冬花 | Common coltsfoot | Tussilago farfara |
H0978 | Di Tao Hua | 地桃花 | Rose mallow | Urena lobata |
H0580 | Tu Si Rou | 菟丝肉 | Dodder seed | Cuscuta australis |
H0939 | Da Xue Teng | 大血藤 | Sargentgloryvine | Sargentodoxa cuneata |
H0463 | Shi Liu Pi | 石榴皮 | Pomegranate peel | Punica granatum |
H0141 | Lian Zi Xin | 莲子心 | Hindu lotus plumule | Nelumbo nucifera |
H0468 | Shi Wei | 石韦 | Japanese felt fern frond | Pyrrosia lingua |
H1045 | Feng Xian Hua | 凤仙花 | Spotted snapweed | Impatiens balsamina |
H1067 | Gan Cao Fen | 甘草粉 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
H0581 | Tu Si Zi | 菟丝子 | Dodder seed | Cuscuta australis |
H0162 | Long Dan | 龙胆 | Rough gentian | Gentiana scabra |
H0411 | Shan Ku Mai | 山苦荬 | China ixeris | Ixeris chinensis |
H0173 | Lu Hui | 芦荟 | Kulaso aloe dried juice | Aloe vera |
H1082 | Gan Lan | 橄榄 | Cabbage | Canarium album |
H0515 | Suan Shi Liu | 酸石榴 | Pomegranate | Punica granatum |
H0750 | Yin Xing Ye | 银杏叶 | Folium ginkgo | Ginkgo biloba |
H1213 | Hu Zhang | 虎杖 | Japanese fleeceflower | Polygonum cuspidatum |
H0519 | Suo Yang | 锁阳 | Songaria cynomorium | Cynomorium songaricum |
H0193 | Ma Bian Cao | 马鞭草 | European verbena | Verbena officinalis |
H1224 | Huai Jiao | 槐角 | pod of japanese pagodatree | Sophora japonica |
H0304 | Ou Pian | 藕片 | Hindu lotus large rhizome | Nelumbo nucifera |
H0067 | Jin Ying Zi | 金樱子 | Cherokee rose seed | Rosa laevigata |
H0871 | Chuan Duan | 川断 | Teasels | Dipsacus asper |
H0485 | Shui Hong Hua | 水红花 | Fructus polygoni orientalis | Polygonum orientale |
H0015 | Ji Xing Zi | 急性子 | Garden balsam seed | Impatiens balsamina |
H0365 | Rou Dou Kou | 肉豆蔻 | Common nutmeg | Myristica fragrans |
H0918 | Cu Yuan Hua | 醋芫花 | Lilac daphne | Daphne genkwa |
H0152 | Ling Zhi Jin Gao | 灵芝浸膏 | NA | Ganoderma lucidum |
H0140 | Lian Zi | 莲子 | Hindu lotus seed | Nelumbo nucifera |
H0847 | Zi He Che | 紫河车 | Human placenta | Homo sapiens |
H0949 | Dan Shen | 丹参 | The root of red-rooted salvia | Salvia miltiorrhiza |
H0422 | Shan Zha Tan | 山楂炭 | Chinese hawthorn | Crataegus pinnatifida |
H0932 | Ba Qia | 菝葜 | Chinaroot greenbrier | Smilax china |
H0486 | Shui Hong Hua Ye | 水红花叶 | Fructus polygoni orientalis | Polygonum orientale |
H0218 | Man Jiu Jie | 蔓九节 | Creeping ninenode | Psychotria serpens |
H0656 | Xiao Bo Gen | 小檗根 | Barberry root | Berberis julianae |
H0798 | Zhen Zhu Cao | 珍珠草 | chamber bitter | Phyllanthus urinaria |
H0805 | Zhi Ke Gan Jin Gao | 枳壳干浸膏 | Seville ora nge unripe fruit | Citrus aurantium |
H0237 | Mei Gui Hua | 玫瑰花 | Rugose rose flower | Rosa rugosa |
H0765 | Chi Dou | 赤豆 | Assuki bean | Vigna angularis |
H0583 | Tu Si Zi Teng | 菟丝子藤 | Dodder seed | Cuscuta australis |
H1016 | Du Zhong Tan | 杜仲炭 | Eucommia | Eucommia ulmoides |
H0440 | Sheng Di Hong Jing Tian | 圣地红景天 | Integripetal rhodiola | Rhodiola sacra |
H0601 | Wu Mei | 乌梅 | Japanese apricot | Prunus mume |
H0354 | Ren Dong Teng | 忍冬藤 | Japanese honeysuckle vine | Lonicera japonica |
H1093 | Gao Liang Jiang You | 高良姜油 | Lesser galangal | Alpinia officinarum |
H1074 | Gan Cao Jin Gao | 甘草浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
H1214 | Hua Jiao | 花椒 | Bunge pricklyash | Zanthoxylum bungeanum |
H0730 | Ye Ma Zhui | 野马追 | NA | Eupatorium lindleyanum |
H1017 | Du Zhong Ye | 杜仲叶 | Eucommia leaf | Eucommia ulmoides |
H1184 | Bai Lian | 白蔹 | Japanese ampelopsis | Ampelopsis japonica |
H0819 | Zhi Zi Jin Gao | 栀子浸膏 | Cape jasmine fruit | Gardenia jasminoides |
H1137 | Gui Yuan | 桂圆 | NA | Dimocarpus longan |
H0926 | Da Huang | 大黄 | Medicinal rhubarb | Rheum officinale |
H0612 | Cao Shan Hu Jin Gao | 草珊瑚浸膏 | NA | Sarcandra glabra |
H1051 | Bai Guo | 白果 | Ginkgo nut | Ginkgo biloba |
H1069 | Gan Cao Gan Gao | 甘草干膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
H0464 | Shi Liu Zi | 石榴子 | NA | Punica granatum |
H0108 | Ku Lian Pi | 苦楝皮 | Chinaberry-tree bark | Melia azedarach |
H0729 | Ye Ju Hua | 野菊花 | Indian wild chrysanthemum flower | Chrysanthemum indicum |
H1240 | Huang Jing Zi | 黄荆子 | NA | Vitex negundo |
H1189 | Hong Jing Tian | 红景天 | all - grass of rhodiola | Radix et rhizoma rhodiolae |
H0990 | Ding Xiang | 丁香 | Clove tree | Syzygium aromaticum |
H0358 | Ren Shen Ye | 人参叶 | Ginseng leaf | Panax ginseng |
H1217 | Bai Mei Hua | 白梅花 | Japanese apricot flower | Prunus mume |
H1028 | Fan Xie Ye | 番泻叶 | Narrowleaf senna leaf | Cassia angustifolia |
H0858 | Zong Lv Pi | 棕榈皮 | Fortune windmillpalm | Trachycarpus fortunei |
H0421 | Shan Zha Qing Gao | 山楂清膏 | Chinese hawthorn | Crataegus pinnatifida |
H0710 | Yuan Hua Tiao | 芫花条 | stem of lilac daphne | Daphne genkwa |
H0960 | Dang Shen Qing Gao | 党参清膏 | Root of hairy asiabell | Codonopsis pilosula |
H1232 | Huang Cao Wu | 黄草乌 | NA | Aconitum vilmorinianum |
H0927 | Da Huang Jin Gao | 大黄浸膏 | Medicinal rhubarb | Rheum officinale |
H0128 | Lao Guan Cao | 老鹳草 | Wilford cranesbill | Geranium wilfordii |
H0453 | Shi Di | 柿蒂 | Persimmon persistent calyx | Diospyros kaki |
H0758 | Cheng Pi | 橙皮 | Bitter orange | Citrus aurantium |
H0166 | Long Kui | 龙葵 | Black nightshade | Solanum nigrum |
H0950 | Dan Shen Gan Jin Gao | 丹参干浸膏 | The root of red-rooted salvia | Salvia miltiorrhiza |
H0498 | Si Ji Cai | 四季菜 | Ghostplant wormwood | Artemisia lactiflora |
H1015 | Du Zhong | 杜仲 | Eucommia | Eucommia ulmoides |
H1099 | Gou Teng | 钩藤 | Sharpleaf gambirplant | Uncaria rhynchophylla |
H0240 | Mi Gan Cao | 蜜甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
H0214 | Bei He Huan | 北合欢 | Albizia | Albizia julibrissin |
H1120 | Guang Huo Xiang | 广藿香 | Patchouli | Pogostemon cablin |
H0707 | Yuan Hua | 芫花 | Lilac daphne | Daphne genkwa |
H0777 | Zao Jia | 皂荚 | Chinese honeylocust | Gleditsia sinensis |
H0734 | Ye Xia Zhu | 叶下珠 | Common leafflower | Phyllanthus urinaria |
H0379 | Bian Xu | 萹蓄 | Common knotgrass | Polygonum aviculare |
H1066 | Gan Cao | 甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
H0415 | Shan Nai | 山柰 | Galanga resurrectionlily | Kaempferia galanga |
H1152 | Bai Jie Zi | 白芥子 | White mustard seed | Sinapis alba |
H0197 | Ma Huang | 麻黄 | Chinese ephedra | Ephedra sinica |
H0733 | Ye Shan Zha | 野山楂 | nippon bawthorn | Crataegus pinnatifida |
H0408 | Bing Lang | 槟榔 | Betenutpalm | Areca catechu |
H0772 | Yue Ji Hua | 月季花 | Chinese rose | Rosa chinensis |
H0938 | Da Suan | 大蒜 | Garlic | Allium sativum |
H0068 | Jin Ying Zi Rou | 金樱子肉 | Cherokee rose seed | Rosa laevigata |
H0163 | Long Dan Jin Gao | 龙胆浸膏 | Rough gentian | Gentiana scabra |
H0035 | Bai Su Zi | 白苏子 | Common perilla fruit | Perilla frutescens |
H0764 | Yu Xing Cao | 鱼腥草 | Heartleaf houttuynia | Houttuynia cordata |
H1164 | He Geng | 荷梗 | Hindu lotus petiole | Nelumbo nucifera |
H0195 | Ma Chi Xian | 马齿苋 | Purslane | Portulaca oleracea |
H0397 | Sang Zhi | 桑枝 | White mulberry branch | Morus alba |
H0301 | Ou | 藕 | Hindu lotus large rhizome | Nelumbo nucifera |
H0975 | Di Mian Cao | 地绵草 | NA | Euphorbia humifusa |
H0444 | Sheng Gan Cao | 生甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
H0153 | Ling Zhi(1) | 灵芝 | Lucid ganoderma | Ganoderma lucidum |
H0941 | Da Zao | 大枣 | Chinese date | Ziziphus jujuba |
H0014 | Bai Rui Cao | 百蕊草 | Chinese bastardtoadflax | Thesium chinense |
H0725 | Yang Xie | 洋泻 | sennoside | Cassia angustifolia |
H0773 | Chi Fu Ling | 赤茯苓 | light red indian bread | Wolfiporia cocos |
H0360 | Ren Zhong Bai | 人中白 | Human urine sediment | Homo sapiens |
H0602 | Wu Mei Rou | 乌梅肉 | Ebony | Prunus mume |
H0928 | Da Huang Liu Jin Gao | 大黄流浸膏 | Medicinal rhubarb | Rheum officinale |
H0084 | Jiu Li Xiang | 九里香 | Common jasminorange | Murraya paniculata |
H0582 | Cao Dou Kou Ren | 草豆蔻仁 | Katsumada galangal | Alpinia katsumadai |
H0565 | Tu Bie Chong | 土鳖虫 | Cockroach | Eupolyphaga sinensis |
H1117 | Guan Zhong | 贯众 | Male fern rhizome | Dryopteris crassirhizoma |
H0679 | Xing Ren | 杏仁 | Apricot seed | Prunus armeniaca |
H1092 | Gao Liang Jiang | 高良姜 | Lesser galangal | Alpinia officinarum |
H1169 | He Ye | 荷叶 | Hindu lotus leaf | Nelumbo nucifera |
H0377 | San Ling | 三棱 | Common burreed | Sparganium stoloniferum |
H0007 | Huo Xue Teng | 活血藤 | NA | Sargentodoxa cuneata |
H0571 | Tu Gan Cao | 土甘草 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
H0825 | Zhu Fu Shen | 朱茯神 | Indian bread with pine | Poria cocos |
H1071 | Gan Cao Gan Jin Gao | 甘草干浸膏 | Glycyrrhiza inflata | Glycyrrhiza uralensis |
H0416 | Shan Shen | 山参 | NA | Panax ginseng |
H0434 | She Pu Tao | 蛇葡萄 | Ampelopsis | Ampelopsis brevipedunculata |
H0980 | Di Yu Tan | 地榆炭 | Garden burnet | Sanguisorba officinalis |
H0005 | Huo Xiang Ye | 藿香叶 | Patchouli | Pogostemon cablin |