Herb Description
| Herb ID: H0925 | Chinese Character: 大腹子 |
| English Name: Areca palm | Latin Name: Areca catechu |
| Chinese Pin Yin : Da Fu Zi | TCM-ID: TCMH358 |
| Therapeutic Function in Chinese : NA | Therapeutic Function in English: NA |
| Herb Function: NA | |
Related Targets (Total: 148)
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
|---|---|---|---|---|
| T98RXH | Focal adhesion kinase 1 | PTK2 |
Q05397 |
1 Reference(s) |
| T12PIB | Lysosomal alpha-glucosidase | GAA |
P10253 |
2 Reference(s) |
| T53RK9 | T-cell surface glycoprotein CD4 | CD4 |
P01730 |
1 Reference(s) |
| T97UTI | 6-phosphogluconate dehydrogenase, decarboxylating | PGD |
P52209 |
2 Reference(s) |
| T74JJN | Fatty acid synthase | FASN |
P49327 |
2 Reference(s) |
| T09TCJ | Taste receptor type 2 member 5 | TAS2R5 |
Q9NYW4 |
1 Reference(s) |
| T20KA8 | Poly(ADP-ribose) glycohydrolase | PARG |
Q86W56 |
1 Reference(s) |
| T78T4E | Hematopoietic prostaglandin D synthase | HPGDS |
O60760 |
1 Reference(s) |
| T25M2J | Anoctamin-1 | ANO1 |
Q5XXA6 |
2 Reference(s) |
| T93WZG | G1/S-specific cyclin-D1 | CCND1 |
P24385 |
1 Reference(s) |
| T06ZFC | Krueppel-like factor 2 | KLF2 |
Q9Y5W3 |
1 Reference(s) |
| T80Q3D | Granzyme B | GZMB |
P10144 |
1 Reference(s) |
| T40MJF | Gamma-aminobutyric acid receptor subunit gamma-1 | GABRG1 |
Q8N1C3 |
1 Reference(s) |
| T23P74 | Caspase-9 | CASP9 |
P55211 |
2 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
5 Reference(s) |
| T80GUN | 72 kDa type IV collagenase | MMP2 |
P08253 |
2 Reference(s) |
| T04H8Y | Beta-secretase 1 | BACE1 |
P56817 |
1 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
2 Reference(s) |
| T06VX0 | MAP/microtubule affinity-regulating kinase 4 | MARK4 |
Q96L34 |
1 Reference(s) |
| T54G8J | Protein kinase C delta type | PRKCD |
Q05655 |
1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
1 Reference(s) |
| T20IHC | Diacylglycerol O-acyltransferase 1 | DGAT1 |
O75907 |
1 Reference(s) |
| T21DZX | Amine oxidase [flavin-containing] A | MAOA |
P21397 |
2 Reference(s) |
| T16UZ4 | Dipeptidyl peptidase 4 | DPP4 |
P27487 |
1 Reference(s) |
| T06MQM | Heat shock protein beta-1 | HSPB1 |
P04792 |
1 Reference(s) |
| T03CZ8 | Catechol O-methyltransferase | COMT |
P21964 |
2 Reference(s) |
| T64UH1 | Nitric oxide synthase, endothelial | NOS3 |
P29474 |
2 Reference(s) |
| T25UYT | Dual specificity mitogen-activated protein kinase kinase 4 | MAP2K4 |
P45985 |
1 Reference(s) |
| T39RV3 | Dual specificity mitogen-activated protein kinase kinase 1 | MAP2K1 |
Q02750 |
1 Reference(s) |
| T75IW3 | Matrix metalloproteinase-14 | MMP14 |
P50281 |
1 Reference(s) |
| T34I45 | Neuronal acetylcholine receptor subunit alpha-7 | CHRNA7 |
P36544 |
1 Reference(s) |
| T16A2X | Catalase | CAT |
P04040 |
3 Reference(s) |
| T70HTD | Cytochrome P450 2E1 | CYP2E1 |
P05181 |
1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
1 Reference(s) |
| T92Q77 | Type I iodothyronine deiodinase | DIO1 |
P49895 |
1 Reference(s) |
| T99EYH | Lipoprotein lipase | LPL |
P06858 |
1 Reference(s) |
| T99W15 | Pancreatic triacylglycerol lipase | PNLIP |
P16233 |
1 Reference(s) |
| T56TXY | Polyunsaturated fatty acid 5-lipoxygenase | ALOX5 |
P09917 |
2 Reference(s) |
| T24LXT | G2/mitotic-specific cyclin-B1 | CCNB1 |
P14635 |
1 Reference(s) |
| T75H3W | Cyclin-dependent kinase 2 | CDK2 |
P24941 |
1 Reference(s) |
| T86UXL | Cyclin-A2 | CCNA2 |
P20248 |
1 Reference(s) |
| T30D9G | Superoxide dismutase [Cu-Zn] | SOD1 |
P00441 |
3 Reference(s) |
| T70SFS | Superoxide dismutase [Mn], mitochondrial | SOD2 |
P04179 |
1 Reference(s) |
| T85NRC | Pyruvate kinase PKM | PKM |
P14618 |
1 Reference(s) |
| T02GD4 | Tumor necrosis factor ligand superfamily member 6 | FASLG |
P48023 |
2 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
2 Reference(s) |
| T97KL5 | Microsomal glutathione S-transferase 1 | MGST1 |
P10620 |
2 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
3 Reference(s) |
| T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
1 Reference(s) |
| T81BH5 | Sulfotransferase 1A1 | SULT1A1 |
P50225 |
2 Reference(s) |
| T32SPJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | PIK3CG |
P48736 |
1 Reference(s) |
| T34DZ7 | Interleukin-2 | IL2 |
P60568 |
1 Reference(s) |
| T28PHS | Angiotensin-converting enzyme | ACE |
P12821 |
1 Reference(s) |
| T23VMI | Tumor necrosis factor | TNF |
P01375 |
3 Reference(s) |
| T26KIE | Transcription factor AP-1 | JUN |
P05412 |
2 Reference(s) |
| T97FEF | Broad substrate specificity ATP-binding cassette transporter ABCG2 | ABCG2 |
Q9UNQ0 |
2 Reference(s) |
| T02P7Q | Dihydrofolate reductase | DHFR |
P00374 |
2 Reference(s) |
| T00H7Q | Neutrophil cytosol factor 1 | NCF1 |
P14598 |
1 Reference(s) |
| T00EP2 | Tissue-type plasminogen activator | PLAT |
P00750 |
2 Reference(s) |
| T84P70 | Urokinase-type plasminogen activator | PLAU |
P00749 |
1 Reference(s) |
| T33OPP | Interleukin-6 | IL6 |
P05231 |
3 Reference(s) |
| T27U96 | Granulocyte-macrophage colony-stimulating factor | CSF2 |
P04141 |
1 Reference(s) |
| T71K92 | Apoptosis regulator Bcl-2 | BCL2 |
P10415 |
2 Reference(s) |
| T35QZO | Cytochrome c | CYCS |
P99999 |
1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
3 Reference(s) |
| T54B00 | P2X purinoceptor 7 | P2RX7 |
Q99572 |
1 Reference(s) |
| T08B2M | M-phase inducer phosphatase 1 | CDC25A |
P30304 |
1 Reference(s) |
| T33UEM | Lactoperoxidase | LPO |
P22079 |
1 Reference(s) |
| T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
1 Reference(s) |
| T03TJ0 | Interleukin-33 | IL33 |
O95760 |
1 Reference(s) |
| T40G6B | Prostaglandin reductase 1 | PTGR1 |
Q14914 |
1 Reference(s) |
| T31VDH | Myeloid differentiation primary response protein MyD88 | MYD88 |
Q99836 |
1 Reference(s) |
| T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
2 Reference(s) |
| T61SU2 | Coxsackievirus and adenovirus receptor | CXADR |
P78310 |
1 Reference(s) |
| T50SX0 | Nuclear receptor subfamily 1 group I member 2 | NR1I2 |
O75469 |
1 Reference(s) |
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
2 Reference(s) |
| T99XJ1 | Serpin H1 | SERPINH1 |
P50454 |
1 Reference(s) |
| T18C4B | Methylated-DNA--protein-cysteine methyltransferase | MGMT |
P16455 |
1 Reference(s) |
| T19F7P | Proteinase-activated receptor 1 | F2R |
P25116 |
1 Reference(s) |
| T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
1 Reference(s) |
| T91T8I | Glucose-6-phosphatase catalytic subunit 1 | G6PC1 |
P35575 |
1 Reference(s) |
| T68R23 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | PCK2 |
Q16822 |
1 Reference(s) |
| T68SE0 | Solute carrier family 2, facilitated glucose transporter member 4 | SLC2A4 |
P14672 |
1 Reference(s) |
| T18DUA | Tight junction protein ZO-1 | TJP1 |
Q07157 |
1 Reference(s) |
| T80U0C | Glutathione synthetase | GSS |
P48637 |
1 Reference(s) |
| T34HYH | Interleukin-1 alpha | IL1A |
P01583 |
1 Reference(s) |
| T84VZG | Ryanodine receptor 1 | RYR1 |
P21817 |
1 Reference(s) |
| T25H22 | Protein kinase C beta type | PRKCB |
P05771 |
2 Reference(s) |
| T78ZF2 | Protein kinase C alpha type | PRKCA |
P17252 |
1 Reference(s) |
| T49XOZ | Krueppel-like factor 7 | KLF7 |
O75840 |
1 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
1 Reference(s) |
| T12T4H | Brain-derived neurotrophic factor | BDNF |
P23560 |
1 Reference(s) |
| T42O1D | Delta-type opioid receptor | OPRD1 |
P41143 |
1 Reference(s) |
| T02QBS | Cytochrome P450 1A2 | CYP1A2 |
P05177 |
1 Reference(s) |
| T76B0A | Gap junction alpha-1 protein | GJA1 |
P17302 |
1 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
1 Reference(s) |
| T64BTV | Interleukin-1 beta | IL1B |
P01584 |
1 Reference(s) |
| T85IZ0 | Opioid-binding protein/cell adhesion molecule | OPCML |
Q14982 |
1 Reference(s) |
| T95IYZ | Adiponectin | ADIPOQ |
Q15848 |
1 Reference(s) |
| T04WT7 | Fibronectin | FN1 |
P02751 |
1 Reference(s) |
| T52GFD | Neuronal acetylcholine receptor subunit alpha-6 | CHRNA6 |
Q15825 |
1 Reference(s) |
| T78IOY | Telomerase reverse transcriptase | TERT |
O14746 |
1 Reference(s) |
| T23TJV | Tyrosine 3-monooxygenase | TH |
P07101 |
1 Reference(s) |
| T78KL2 | Collagen alpha-1(III) chain | COL3A1 |
P02461 |
1 Reference(s) |
| T43N2D | Epidermal growth factor receptor | EGFR |
P00533 |
1 Reference(s) |
| T15VAS | Integrin beta-1 | ITGB1 |
P05556 |
1 Reference(s) |
| T27LA6 | DNA | DNMT1 |
P26358 |
1 Reference(s) |
| T64V6C | Glutamate decarboxylase 1 | GAD1 |
Q99259 |
1 Reference(s) |
| T44LWL | Transcription factor p65 | RELA |
Q04206 |
1 Reference(s) |
| T10HL8 | Intercellular adhesion molecule 1 | ICAM1 |
P05362 |
1 Reference(s) |
| T02DYS | Protein fosB | FOSB |
P53539 |
1 Reference(s) |
| T17CZC | Tissue factor | F3 |
P13726 |
1 Reference(s) |
| T96OOK | Signal transducer and activator of transcription 3 | STAT3 |
P40763 |
1 Reference(s) |
| T14LSK | E3 ubiquitin-protein ligase XIAP | XIAP |
P98170 |
1 Reference(s) |
| T36B1Q | Baculoviral IAP repeat-containing protein 5 | BIRC5 |
O15392 |
1 Reference(s) |
| T17UP9 | C-C motif chemokine 2 | CCL2 |
P13500 |
1 Reference(s) |
| T32IXS | Integrin alpha-M | ITGAM |
P11215 |
1 Reference(s) |
| T91F6Z | Integrin alpha-L | ITGAL |
P20701 |
1 Reference(s) |
| T25C2G | Nuclear receptor subfamily 4 group A member 1 | NR4A1 |
P22736 |
1 Reference(s) |
| T37ADS | Early growth response protein 1 | EGR1 |
P18146 |
1 Reference(s) |
| T50V79 | Interleukin-4 | IL4 |
P05112 |
1 Reference(s) |
| T69NG6 | Interleukin-10 | IL10 |
P22301 |
1 Reference(s) |
| T62P0D | Collagenase 3 | MMP13 |
P45452 |
1 Reference(s) |
| T20H9F | Stromelysin-1 | MMP3 |
P08254 |
1 Reference(s) |
| T03O7G | Orexin | HCRT |
O43612 |
1 Reference(s) |
| T82RFG | P2Y purinoceptor 12 | P2RY12 |
Q9H244 |
1 Reference(s) |
| T73WJH | Calcium/calmodulin-dependent protein kinase kinase 2 | CAMKK2 |
Q96RR4 |
1 Reference(s) |
| T63GUB | Proto-oncogene c-Fos | FOS |
P01100 |
1 Reference(s) |
| T45G32 | Proto-oncogene tyrosine-protein kinase Src | SRC |
P12931 |
1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
1 Reference(s) |
| T80TUC | Apoptosis regulator BAX | BAX |
Q07812 |
1 Reference(s) |
| T01P7T | Retinoic acid receptor RXR-beta | RXRB |
P28702 |
1 Reference(s) |
| T75OVL | High affinity nerve growth factor receptor | NTRK1 |
P04629 |
2 Reference(s) |
| T31P1D | Metalloproteinase inhibitor 1 | TIMP1 |
P01033 |
1 Reference(s) |
| T85AB0 | Metalloproteinase inhibitor 4 | TIMP4 |
Q99727 |
1 Reference(s) |
| T85HMF | Metalloproteinase inhibitor 3 | TIMP3 |
P35625 |
1 Reference(s) |
| T80OJF | Interstitial collagenase | MMP1 |
P03956 |
1 Reference(s) |
| T64T6J | Beta-1 adrenergic receptor | ADRB1 |
P08588 |
1 Reference(s) |
| T63M1G | Integrin alpha-2 | ITGA2 |
P17301 |
1 Reference(s) |
| T86ROZ | Heme oxygenase 1 | HMOX1 |
P09601 |
1 Reference(s) |
| T01E8J | Amyloid-beta precursor protein | APP |
P05067 |
1 Reference(s) |
| T56G7O | Acyl-CoA-binding protein | DBI |
P07108 |
1 Reference(s) |
| T54CIF | Interleukin-8 | CXCL8 |
P10145 |
1 Reference(s) |
| T28HOM | Leptin | LEP |
P41159 |
1 Reference(s) |
| T24U57 | E-selectin | SELE |
P16581 |
1 Reference(s) |
| T59IKQ | Vascular cell adhesion protein 1 | VCAM1 |
P19320 |
1 Reference(s) |
| T13HLX | cAMP-specific 3',5'-cyclic phosphodiesterase 4B (EC 3.1.4.53) (DPDE4) (PDE32) | PDE4B |
Q07343 |
1 Reference(s) |
| T18CPB | Choline O-acetyltransferase | CHAT |
P28329 |
1 Reference(s) |
Related Compounds (Total: 12)
C1220
Name: Catechin
C0306
Name: Physcion
C0426
Name: Tannic Acid
C1240
Name: Chrysophanol
C0150
Name: Isoguvacine
key description of the interaction between compound and target