HIT-result

Target Description

Type	Detail
Target ID	T78T4E
Protein Name	Hematopoietic prostaglandin D synthase
Uniprot ID	O60760
Protein Name Alias	H-PGDS; EC 5.3.99.2; GST class-sigma; Glutathione S-transferase; EC 2.5.1.18; Glutathione-dependent PGD synthase; Glutathione-requiring prostaglandin D synthase; Prostaglandin-H2 D-isomerase
Gene ID	27306
Gene Symbol	HPGDS
Gene Alias	GSTS; PGDS; PTGDS2
TTD	T19433: Successful target
Pfam	PF02798 ; PF14497
GO	0007626:locomotory behavior 0019371:cyclooxygenase pathway 0043231:intracellular membrane-bounded organelle 0005737:cytoplasm 0004364:glutathione transferase activity 0042803:protein homodimerization activity 0006693:prostaglandin metabolic process 0007165:signal transduction 0005654:nucleoplasm 0004667:prostaglandin-D synthase activity 1901687:glutathione derivative biosynthetic process 0005509:calcium ion binding 0005829:cytosol 0006749:glutathione metabolic process 0000287:magnesium ion binding
PDB	3VI5 ; 5YX1 ; 4EDY ; 5AIV ; 1IYI ; 2VD0 ; 5YWE ; 2VCW ; 5AIS ; 4EDZ ; 3KXO ; 2VCQ ; 2CVD ; 1V40 ; 2VD1 ; 3EE2 ; 6N4E ; 6W58 ; 2VCX ; 2VCZ ; 5YWX ; 6W8H ; 1IYH ; 5AIX ; 4EE0 ; 4EC0 ; 3VI7
Drugbank	DB07615 ; DB00143 ; DB08313 ; DB07613 ; DB07616 ; DB08790 ; DB07917 ; DB03310 ; DB08695 ; DB01897 ; DB00755 ; DB07614
KEGG	hsa:27306

Type

Detail

Target ID

T78T4E

Protein Name

Hematopoietic prostaglandin D synthase

Uniprot ID

O60760

Protein Name Alias

H-PGDS; EC 5.3.99.2; GST class-sigma; Glutathione S-transferase; EC 2.5.1.18; Glutathione-dependent PGD synthase; Glutathione-requiring prostaglandin D synthase; Prostaglandin-H2 D-isomerase

Gene ID

27306

Gene Symbol

HPGDS

Gene Alias

GSTS; PGDS; PTGDS2

TTD

T19433: Successful target

Pfam

PF02798 ; PF14497

0007626:locomotory behavior

0019371:cyclooxygenase pathway

0043231:intracellular membrane-bounded organelle

0005737:cytoplasm

0004364:glutathione transferase activity

0042803:protein homodimerization activity

0006693:prostaglandin metabolic process

0007165:signal transduction

0005654:nucleoplasm

0004667:prostaglandin-D synthase activity

1901687:glutathione derivative biosynthetic process

0005509:calcium ion binding

0005829:cytosol

0006749:glutathione metabolic process

0000287:magnesium ion binding

PDB

3VI5 ; 5YX1 ; 4EDY ; 5AIV ; 1IYI ; 2VD0 ; 5YWE ; 2VCW ; 5AIS ; 4EDZ ; 3KXO ; 2VCQ ; 2CVD ; 1V40 ; 2VD1 ; 3EE2 ; 6N4E ; 6W58 ; 2VCX ; 2VCZ ; 5YWX ; 6W8H ; 1IYH ; 5AIX ; 4EE0 ; 4EC0 ; 3VI7

Drugbank

DB07615 ; DB00143 ; DB08313 ; DB07613 ; DB07616 ; DB08790 ; DB07917 ; DB03310 ; DB08695 ; DB01897 ; DB00755 ; DB07614

KEGG

hsa:27306

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0895	Chuan Yu Jin	川郁金	Turmeric	Curcuma longa
H0028	Jiang Huang	姜黄	Common turmeric	Curcuma longa
H0802	Zhi Geng	枳梗	NA	Citrus aurantium
H0016	Ji Xue Cao	积雪草	Asiatic pennywort	Centella asiatica
H0142	Liang Jiang	良姜	NA	Alpinia officinarum
H1171	He Zi Rou	诃子肉	Medicine terminalia	Terminalia chebula
H0053	Jin Lian Hua	金莲花	Chinese globeflower	Trollius chinensis
H0761	Yu Jin	郁金	AromaticTurmeric	Curcuma aromatica
H0804	Zhi Ke	枳壳	Seville ora nge unripe fruit	Citrus aurantium
H0805	Zhi Ke Gan Jin Gao	枳壳干浸膏	Seville ora nge unripe fruit	Citrus aurantium
H0925	Da Fu Zi	大腹子	Areca palm	Areca catechu
H0618	Cao Wu	草乌	Kusnezoff monkshood root	Aconitum carmichaelii
H1092	Gao Liang Jiang	高良姜	Lesser galangal	Alpinia officinarum
H0758	Cheng Pi	橙皮	Bitter orange	Citrus aurantium
H0556	Tie Xian Cao	铁线草	NA	Adiantum capillus-veneris
H0408	Bing Lang	槟榔	Betenutpalm	Areca catechu
H0446	Sheng Jiang	生姜	Fresh common ginger	Zingiber officinale
H0547	Cang Qing Guo	藏青果	Myrobalan	Terminalia chebula
H0813	Zhi Shi	枳实	Seville orange young fruit	Citrus aurantium
H1172	Hei Cao Wu	黑草乌	Kusnezoff monkshood root	Radix aconiti kusnezoffii
H1093	Gao Liang Jiang You	高良姜油	Lesser galangal	Alpinia officinarum
H1170	He Zi	诃子	Medicine terminalia	Terminalia chebula

Target Description

Related Compounds (Total: 3)

Related Herbs (Total: 22)