Target Description

Type Detail
Target ID T23TJV
Protein Name Tyrosine 3-monooxygenase
Uniprot ID P07101
Protein Name Alias EC 1.14.16.2;  Tyrosine 3-hydroxylase;  TH
Gene ID 7054
Gene Symbol TH
Gene Alias TYH
TTD T62390: Successful target
Pfam PF12549 ; PF00351
GO
0071312:cellular response to alkaloid

0035690:cellular response to drug

0016597:amino acid binding

0034617:tetrahydrobiopterin binding

0007612:learning

0048596:embryonic camera-type eye morphogenesis

0043195:terminal bouton

0007601:visual perception

0071333:cellular response to glucose stimulus

0043473:pigmentation

0035240:dopamine binding

0007617:mating behavior

0032355:response to estradiol

0016137:glycoside metabolic process

0008016:regulation of heart contraction

0007613:memory

0042755:eating behavior

0009653:anatomical structure morphogenesis

0033076:isoquinoline alkaloid metabolic process

0071363:cellular response to growth factor stimulus

0006585:dopamine biosynthetic process from tyrosine

0035176:social behavior

0035902:response to immobilization stress

0045471:response to ethanol

0009635:response to herbicide

0014823:response to activity

0007626:locomotory behavior

0030425:dendrite

0071316:cellular response to nicotine

0001666:response to hypoxia

0035900:response to isolation stress

0046684:response to pyrethroid

0042802:identical protein binding

0005790:smooth endoplasmic reticulum

0019825:oxygen binding

0019899:enzyme binding

0042416:dopamine biosynthetic process

0048471:perinuclear region of cytoplasm

0015842:aminergic neurotransmitter loading into synaptic vesicle

0021987:cerebral cortex development

0071287:cellular response to manganese ion

0006665:sphingolipid metabolic process

0042214:terpene metabolic process

0051602:response to electrical stimulus

0001963:synaptic transmission, dopaminergic

0042745:circadian sleep/wake cycle

0030424:axon

0031667:response to nutrient levels

0008198:ferrous iron binding

0007507:heart development

0032496:response to lipopolysaccharide

0009414:response to water deprivation

0043434:response to peptide hormone

0009651:response to salt stress

0008199:ferric iron binding

0010259:multicellular organism aging

0006631:fatty acid metabolic process

0007605:sensory perception of sound

0005739:mitochondrion

0042462:eye photoreceptor cell development

0009416:response to light stimulus

0005634:nucleus

0004511:tyrosine 3-monooxygenase activity

0042423:catecholamine biosynthetic process

0042418:epinephrine biosynthetic process

0045472:response to ether

0009898:cytoplasmic side of plasma membrane

0008021:synaptic vesicle

1990384:hyaloid vascular plexus regression

0019904:protein domain specific binding

0042421:norepinephrine biosynthetic process

0003007:heart morphogenesis

0005829:cytosol

0042136:neurotransmitter biosynthetic process

0051412:response to corticosterone

0052314:phytoalexin metabolic process

0043204:perikaryon

0043005:neuron projection

0005737:cytoplasm

0010043:response to zinc ion

0001975:response to amphetamine

0033162:melanosome membrane

0009887:animal organ morphogenesis

0018963:phthalate metabolic process

0031410:cytoplasmic vesicle

PDB 2XSN ; 4J6S
Drugbank DB00360 ; DB00765 ; DB00120 ; DB04400 ; DB00135 ; DB03552
KEGG hsa:7054

Related Compounds  (Total: 16)

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C0034
Name: Dopamine
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C0035
Name: Dronabinol
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C0055
Name: Estradiol
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C0059
Name: Ethinyl Estradiol
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C0226
Name: Morphine


Related Herbs  (Total: 82)

Herb idChinese Pin YinChinese CharacterEnglish NameLatin Name
H0437 She Xiang麝香 AbelmuskMoschus moschiferus
H0292 Niu Jiao Jian Fen牛角尖粉 Buffalo hornBubalus bubalis
H0785 Ze Xi Huang Lian择细黄连 Coptis deltoideaCoptis chinensis
H0757 Ying Su Ke罂粟壳 Opium poppy pericarpPapaver somniferum
H0864 Cu Jiang Cao酢浆草 Creeping oxalisOxalis corniculata
H0029 Jiang Huang Lian姜黄连 Coptis deltoideaCoptis chinensis
H0360 Ren Zhong Bai人中白 Human urine sedimentHomo sapiens
H0248 Mi Ying Su Ke蜜罂粟壳 Opium poppyPapaver somniferum
H0925 Da Fu Zi大腹子 Areca palmAreca catechu
H1033 Fang Ji防己 Fourstamen stephaniaStephania tetrandra
H0077 Jiu EthanolVinum
H0697 Ya Ma Zi亚麻子 Common flax seedLinum usitatissimum
H0376 San Ke Zhen Pi三棵针皮 root or bark of reddrop barberryCortex berberidis
H0383 San Qi Jing Ye三七茎叶 SanchiPanax notoginseng
H0051 Jin Guo Lan金果榄 Hairystalk tinosporaTinospora capillipes
H0563 Tou Gu Xiang透骨香 NAGaultheria yunnanensis
H0214 Bei He Huan北合欢 AlbiziaAlbizia julibrissin
H0637 Cha Ye茶叶 Common teaCamellia sinensis
H0960 Dang Shen Qing Gao党参清膏 Root of hairy asiabellCodonopsis pilosula
H0505 Cang Chang Pu藏菖蒲 Sweet flagAcorus calamus
H0683 Xiu Xian Ju绣线菊 Japanese spiraeaSpiraea japonica
H0669 Xie Bai薤白 Longstamen onionAllium macrostemon
H0872 Chuan Huang Lian川黄连 rhizome of chinese goldthreadCoptis chinensis
H0520 Tai Pan Fen胎盘粉 Fetus powderHuman placenta
H0084 Jiu Li Xiang九里香 Common jasminorangeMurraya paniculata
H0082 Jiu Huang Lian酒黄连 Coptis deltoideaCoptis chinensis
H0205 Ma Wei Lian马尾连 Manyleaf meadowrueThalictrum foliolosum
H0682 Xiong Huang Lian雄黄连 Coptis deltoideaCoptis chinensis
H0704 Yan Guan Huang Bai盐关黄柏 Amur cork treePhellodendron amurense
H0356 Ren Gong She Xiang人工麝香 AbelmuskMoschus moschiferus
H0195 Ma Chi Xian马齿苋 PurslanePortulaca oleracea
H0370 Ru Xiang乳香 OlibanumBoswellia carterii
H1102 Gu Sui Bu骨碎补 Fortune’s drynaria rhizomeDrynaria fortunei
H0003 Huo Ma Ren火麻仁 Hemp fimble seedCannabis sativa
H1176 Hei Hu Jiao黑胡椒 Black pepperPiper nigrum
H1169 He Ye荷叶 Hindu lotus leafNelumbo nucifera
H0384 San Qi Ye三七叶 Folium panax notoginsengPanax notoginseng
H0732 Ye Mu Dan野牡丹 Common melastomaMelastoma candidum
H0381 San Qi Gao Fen三七膏粉 SanchiPanax notoginseng
H1241 Huang Lian黄连 Coptis deltoideaCoptis chinensis
H1230 Huang Bai Fen黄柏粉 Amur corktreePhellodendron amurense
H0236 Mao She Xiang Jin Gao毛麝香浸膏 AbelmuskMoschus moschiferus
H0385 San Qi Ye Jing三七叶茎 SanchiPanax notoginseng
H0065 Jin Yin Hua Ti Qu Ye金银花提取液 Japanese honeysuckleLonicera japonica
H1004 Bai Cha白茶 White teaCamellia sinensis
H0382 San Qi Hua三七花 SanchiPanax notoginseng
H0756 Ying Su罂粟 Opium poppyPapaver somniferum
H0958 Dang Shen党参 Pilose asiabellCodonopsis pilosula
H0354 Ren Dong Teng忍冬藤 Japanese honeysuckle vineLonicera japonica
H0064 Jin Yin Hua金银花 Japanese honeysuckleLonicera japonica
H0487 Shui Niu Jiao水牛角 Buffalo hornBubalus bubalis
H0291 Niu Jiao Fen牛角粉 Buffalo hornBubalus bubalis
H0275 Mu Zei木贼 Common scouring rushEquisetum hiemale
H0643 Xiang Jiao橡胶 RubberMusa paradisiaca var. sapientum
H0257 Mo Gu蘑菇 MushroomAgaricus campestris
H0489 Shui Niu Jiao Nong Suo Fen水牛角浓缩粉 Buffalo hornBubalus bubalis
H1196 Hou Pu厚朴 bark of officinal magnoliaCortex magnoliae officinalis
H1204 Hu Jiao胡椒 Black pepperPiper nigrum
H0408 Bing Lang槟榔 BetenutpalmAreca catechu
H0235 Mao She Xiang毛麝香 AbelmuskMoschus moschiferus
H0706 Yan Hu Suo延胡索 YanhusuoCorydalis yanhusuo
H0204 Ma Ren麻仁 NACannabis sativa
H0293 Niu Jiao Tan牛角炭 Buffalo hornBubalus bubalis
H0258 Mo Han Lian墨旱莲 YerbadetajoEclipta prostrata
H1243 Huang Lian Xu黄连须 Coptis deltoideaCoptis chinensis
H1077 Bai Hu Jiao白胡椒 white pepperPiper nigrum
H1226 Huai Shan Yao淮山药 rhizome of biglcaf yamRhizoma dioscoreae
H0847 Zi He Che紫河车 Human placentaHomo sapiens
H1231 Huang Bai Tan黄柏炭 Amur corktreePhellodendron amurense
H0521 Tai Pan Zu Zhi Fen胎盘组织粉 NAHuman placenta
H1228 Huang Bai黄柏 Amur corktreePhellodendron amurense
H0140 Lian Zi莲子 Hindu lotus seedNelumbo nucifera
H0375 San Ke Zhen三棵针 root or bark of reddrop barberryCortex berberidis
H0661 Xiao Hei Dou小黑豆 Black turtle beanPhaseolus vulgaris
H1115 Guan Huang Bai关黄柏 Amur cork treePhellodendron amurense
H0467 Shi Shang Bai石上柏 Doederlein's spikemoss herbHerba selaginellae doederleinii
H0035 Bai Su Zi白苏子 Common perilla fruitPerilla frutescens
H0633 Xia Tian Wu夏天无 Decumbent corydalisCorydalis decumbens
H0380 San Qi Gan Jin Gao三七干浸膏 SanchiPanax notoginseng
H1242 Huang Lian Gan Jin Gao黄连干浸膏 Coptis deltoideaCoptis chinensis
H0488 Shui Niu Jiao Gan Jin Gao水牛角干浸膏 Buffalo hornBubalus bubalis
H0760 Yu Huang Lian萸黄连 Coptis deltoideaCoptis chinensis