Herb Description
| Herb ID: H0706 | Chinese Character: 延胡索 |
| English Name: Yanhusuo | Latin Name: Corydalis yanhusuo |
| Chinese Pin Yin : Yan Hu Suo | TCM-ID: TCMH2376 |
| Therapeutic Function in Chinese : 活血化淤 | Therapeutic Function in English: Blood activation and stasis removal |
| Herb Function: Invigorate blood and promote qi circulation, stop pain | |
Related Targets (Total: 89)
| Target id | Protein Name | Gene Symbol | Uniprot ID | No.of Literature Evidence |
|---|---|---|---|---|
| T67JME | Gamma-aminobutyric acid receptor subunit rho-3 | GABRR3 |
A8MPY1 |
1 Reference(s) |
| T40MJF | Gamma-aminobutyric acid receptor subunit gamma-1 | GABRG1 |
Q8N1C3 |
4 Reference(s) |
| T41Z1X | Gamma-aminobutyric acid receptor-associated protein | GABARAP |
O95166 |
4 Reference(s) |
| T37CD6 | Gamma-aminobutyric acid receptor subunit gamma-2 | GABRG2 |
P18507 |
4 Reference(s) |
| T56MO9 | Gamma-aminobutyric acid receptor subunit alpha-3 | GABRA3 |
P34903 |
1 Reference(s) |
| T87UF3 | Gamma-aminobutyric acid receptor subunit beta-3 | GABRB3 |
P28472 |
1 Reference(s) |
| T83P5X | Inhibitor of nuclear factor kappa-B kinase subunit beta | IKBKB |
O14920 |
1 Reference(s) |
| T81I4T | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | PRKAA1 |
Q13131 |
3 Reference(s) |
| T74QXI | Serine/threonine-protein kinase mTOR | MTOR |
P42345 |
1 Reference(s) |
| T49ORJ | Peroxisome proliferator-activated receptor alpha | PPARA |
Q07869 |
3 Reference(s) |
| T70HTD | Cytochrome P450 2E1 | CYP2E1 |
P05181 |
1 Reference(s) |
| T04H8Y | Beta-secretase 1 | BACE1 |
P56817 |
1 Reference(s) |
| T33OSQ | Sterol regulatory element-binding protein 1 | SREBF1 |
P36956 |
1 Reference(s) |
| T26KIE | Transcription factor AP-1 | JUN |
P05412 |
2 Reference(s) |
| T76SUY | Solute carrier family 22 member 2 | SLC22A2 |
O15244 |
3 Reference(s) |
| T43N2D | Epidermal growth factor receptor | EGFR |
P00533 |
2 Reference(s) |
| T57FUN | Beclin-1 | BECN1 |
Q14457 |
1 Reference(s) |
| T71BDH | Mitogen-activated protein kinase 14 | MAPK14 |
Q16539 |
2 Reference(s) |
| T22OPB | Nuclear factor erythroid 2-related factor 2 | NFE2L2 |
Q16236 |
1 Reference(s) |
| T85U8U | Caspase-3 | CASP3 |
P42574 |
1 Reference(s) |
| T83YZD | Acetylcholinesterase | ACHE |
P22303 |
1 Reference(s) |
| T98RXH | Focal adhesion kinase 1 | PTK2 |
Q05397 |
1 Reference(s) |
| T11ZYR | Cytochrome P450 2D6 | CYP2D6 |
P10635 |
1 Reference(s) |
| T83ENN | Solute carrier family 22 member 3 | SLC22A3 |
O75751 |
1 Reference(s) |
| T09H2Z | Nitric oxide synthase, inducible | NOS2 |
P35228 |
1 Reference(s) |
| T38OH4 | Caspase-1 | CASP1 |
P29466 |
1 Reference(s) |
| T68XO1 | Indoleamine 2,3-dioxygenase 1 | IDO1 |
P14902 |
2 Reference(s) |
| T14V9R | Dihydroorotate dehydrogenase | DHODH |
Q02127 |
1 Reference(s) |
| T23TJV | Tyrosine 3-monooxygenase | TH |
P07101 |
1 Reference(s) |
| T88AJI | Hypoxia-inducible factor 1-alpha | HIF1A |
Q16665 |
2 Reference(s) |
| T02U6A | Metabotropic glutamate receptor 1 | GRM1 |
Q13255 |
1 Reference(s) |
| T64P00 | Metabotropic glutamate receptor 5 | GRM5 |
P41594 |
1 Reference(s) |
| T63GUB | Proto-oncogene c-Fos | FOS |
P01100 |
3 Reference(s) |
| T95GWW | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | PDE4A |
P27815 |
1 Reference(s) |
| T76B0A | Gap junction alpha-1 protein | GJA1 |
P17302 |
1 Reference(s) |
| T31XSX | Gap junction beta-1 protein | GJB1 |
P08034 |
1 Reference(s) |
| T96OOK | Signal transducer and activator of transcription 3 | STAT3 |
P40763 |
1 Reference(s) |
| T92P67 | Vasodilator-stimulated phosphoprotein | VASP |
P50552 |
2 Reference(s) |
| T67KTV | Transient receptor potential cation channel subfamily V member 1 | TRPV1 |
Q8NER1 |
1 Reference(s) |
| T45XTW | Retinoic acid receptor RXR-alpha | RXRA |
P19793 |
1 Reference(s) |
| T52XO3 | Cytochrome P450 2J2 | CYP2J2 |
P51589 |
1 Reference(s) |
| T58J2Y | Peroxisome proliferator-activated receptor gamma | PPARG |
P37231 |
1 Reference(s) |
| T54SZZ | Endoplasmic reticulum chaperone BiP | HSPA5 |
P11021 |
1 Reference(s) |
| T06Q1R | Amine oxidase [flavin-containing] B | MAOB |
P27338 |
1 Reference(s) |
| T21DZX | Amine oxidase [flavin-containing] A | MAOA |
P21397 |
2 Reference(s) |
| T50WOV | ATP-dependent translocase ABCB1 | ABCB1 |
P08183 |
2 Reference(s) |
| T42EAZ | Vascular endothelial growth factor A | VEGFA |
P15692 |
2 Reference(s) |
| T73QZ2 | Methylcytosine dioxygenase TET2 | TET2 |
Q6N021 |
1 Reference(s) |
| T92XYL | Glutamate receptor ionotropic, NMDA 2D | GRIN2D |
O15399 |
1 Reference(s) |
| T45C0Q | Gonadotropin-releasing hormone receptor | GNRHR |
P30968 |
1 Reference(s) |
| T20JZ2 | Androgen receptor | AR |
P10275 |
1 Reference(s) |
| T32GWR | Ephrin-B2 | EFNB2 |
P52799 |
3 Reference(s) |
| T95IYZ | Adiponectin | ADIPOQ |
Q15848 |
1 Reference(s) |
| T38H79 | Membrane protein MLC1 | MLC1 |
Q15049 |
1 Reference(s) |
| T62R6K | Myosin light chain kinase 3 | MYLK3 |
Q32MK0 |
1 Reference(s) |
| T45G32 | Proto-oncogene tyrosine-protein kinase Src | SRC |
P12931 |
1 Reference(s) |
| T80OJF | Interstitial collagenase | MMP1 |
P03956 |
2 Reference(s) |
| T49TDM | Matrix metalloproteinase-9 | MMP9 |
P14780 |
2 Reference(s) |
| T78OTS | APC membrane recruitment protein 1 | AMER1 |
Q5JTC6 |
1 Reference(s) |
| T27LA6 | DNA | DNMT1 |
P26358 |
1 Reference(s) |
| T28HOM | Leptin | LEP |
P41159 |
1 Reference(s) |
| T38WWN | Serum paraoxonase/arylesterase 1 | PON1 |
P27169 |
1 Reference(s) |
| T28K6X | Insulin receptor substrate 1 | IRS1 |
P35568 |
1 Reference(s) |
| T70VB4 | Cortistatin | CORT |
O00230 |
1 Reference(s) |
| T20E5P | Cytochrome b-245 heavy chain | CYBB |
P04839 |
1 Reference(s) |
| T88TDZ | RAC-alpha serine/threonine-protein kinase | AKT1 |
P31749 |
1 Reference(s) |
| T09HVO | Sodium/hydrogen exchanger 3 | SLC9A3 |
P48764 |
1 Reference(s) |
| T94H37 | Cadherin-1 | CDH1 |
P12830 |
1 Reference(s) |
| T10ICM | Oxidized low-density lipoprotein receptor 1 | OLR1 |
P78380 |
1 Reference(s) |
| T80XW6 | Scavenger receptor class B member 1 | SCARB1 |
Q8WTV0 |
1 Reference(s) |
| T75PC7 | NA | MIR21 |
NA |
2 Reference(s) |
| T38JCD | DNA-binding protein inhibitor ID-1 | ID1 |
P41134 |
1 Reference(s) |
| T58K2N | Calmodulin-3;Calmodulin-1;Calmodulin-2 | CALM3;CALM1;CALM2 |
P0DP25;P0DP23;P0DP24 |
1 Reference(s) |
| T40W2M | NA | MIR93 |
NA |
1 Reference(s) |
| T90HSB | NA | MIR373 |
NA |
1 Reference(s) |
| T29C6N | Ezrin | EZR |
P15311 |
1 Reference(s) |
| T92BZ2 | Catenin beta-1 | CTNNB1 |
P35222 |
1 Reference(s) |
| T31P1D | Metalloproteinase inhibitor 1 | TIMP1 |
P01033 |
2 Reference(s) |
| T06RMZ | Nuclear factor NF-kappa-B p105 subunit | NFKB1 |
P19838 |
2 Reference(s) |
| T20H9F | Stromelysin-1 | MMP3 |
P08254 |
1 Reference(s) |
| T62P0D | Collagenase 3 | MMP13 |
P45452 |
1 Reference(s) |
| T67ZT3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | PTEN |
P60484 |
2 Reference(s) |
| T26CFB | DNA damage-inducible transcript 3 protein | DDIT3 |
P35638;P0DPQ6 |
1 Reference(s) |
| T82JWE | Cellular tumor antigen p53 | TP53 |
P04637 |
1 Reference(s) |
| T08Q7W | Prostaglandin G/H synthase 2 | PTGS2 |
P35354 |
1 Reference(s) |
| T33BF9 | DNA | DNMT3B |
Q9UBC3 |
1 Reference(s) |
| T34WFL | Proto-oncogene tyrosine-protein kinase receptor Ret | RET |
P07949 |
1 Reference(s) |
| T25YP8 | Aquaporin-4 | AQP4 |
P55087 |
1 Reference(s) |
| T79WXA | Mitogen-activated protein kinase 1 | MAPK1 |
P28482 |
1 Reference(s) |
Related Compounds (Total: 8)
C0602
Name: 2,3,9,10-Tetramethoxy-6,8,13,13A-Tetrahydro-5H-Isoquinolino[2,1-B]Isoquinoline
C0086
Name: Fumaric Acid
C1183
Name: Bicuculline
C1171
Name: Berberine
C0439
Name: Tetrahydropalmatine
key description of the interaction between compound and target