HIT-result

Type	Detail
Target ID	T14V9R
Protein Name	Dihydroorotate dehydrogenase
Uniprot ID	Q02127
Protein Name Alias	quinone; DHOdehase; EC 1.3.5.2; Dihydroorotate oxidase
Gene ID	1723
Gene Symbol	DHODH
Gene Alias	NA
TTD	T61400: Successful target
Pfam	PF01180
GO	0010181:FMN binding 0044205:'de novo' UMP biosynthetic process 0006207:'de novo' pyrimidine nucleobase biosynthetic process 0005829:cytosol 0007595:lactation 0016021:integral component of membrane 0090140:regulation of mitochondrial fission 0042493:response to drug 1903576:response to L-arginine 0008144:drug binding 0031000:response to caffeine 0043065:positive regulation of apoptotic process 0005739:mitochondrion 0004152:dihydroorotate dehydrogenase activity 0005743:mitochondrial inner membrane 0005654:nucleoplasm 0043025:neuronal cell body 0007565:female pregnancy 0048039:ubiquinone binding 0042594:response to starvation 0009220:pyrimidine ribonucleotide biosynthetic process 0046134:pyrimidine nucleoside biosynthetic process
PDB	2PRH ; 4JTS ; 4LS2 ; 5H73 ; 4JTU ; 5HQE ; 5TCE ; 5ZFB ; 4LS0 ; 5ZF4 ; 3G0U ; 6SYP ; 2WV8 ; 2PRL ; 3FJL ; 3KVM ; 6LP8 ; 6OC1 ; 6LP6 ; 4OQV ; 5K9D ; 5K9C ; 6JME ; 3W7R ; 6LZL ; 5MUT ; 2PRM ; 5MVC ; 3KVK ; 4RLI ; 6J3B ; 2B0M ; 6FMD ; 6JMD ; 2FQI ; 3KVL ; 2FPY ; 5ZF8 ; 2FPT ; 4YLW ; 1D3G ; 6CJF ; 3KVJ ; 2FPV ; 7K2U ; 3G0X ; 5ZFA ; 6GK0 ; 5H2Z ; 3FJ6 ; 6ET4 ; 6QU7 ; 4LS1 ; 4JGD ; 3U2O ; 4RK8 ; 3ZWS ; 6J3C ; 1D3H ; 6IDJ ; 3ZWT ; 5ZF9 ; 4ZL1 ; 3F1Q ; 6LP7 ; 5ZF7 ; 4RKA ; 4JS3 ; 4RR4 ; 5MVD ; 4IGH ; 4ZMG ; 6OC0 ; 4JTT ; 6VND ; 5HIN ; 2BXV ; 6CJG
Drugbank	DB07977 ; DB08249 ; DB07975 ; DB07976 ; DB04281 ; DB07443 ; DB08006 ; DB07646 ; DB07561 ; DB02262 ; DB01117 ; DB07978 ; DB06481 ; DB04147 ; DB03480 ; DB01097 ; DB08172 ; DB05125 ; DB04583 ; DB08008 ; DB08169 ; DB07559 ; DB03523 ; DB08880 ; DB03247 ; DB02613
KEGG	hsa:1723

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Name: Coptisine

Herb id	Chinese Pin Yin	Chinese Character	English Name	Latin Name
H0706	Yan Hu Suo	延胡索	Yanhusuo	Corydalis yanhusuo
H0006	Bai Qu Cai	白屈菜	Greater celandine	Chelidonium majus
H1241	Huang Lian	黄连	Coptis deltoidea	Coptis chinensis